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Nivetha Brathaban
Nivetha Brathaban
Researcher
在 nurixtx.com 的电子邮件经过验证
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引用次数
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Plasma glial fibrillary acidic protein levels differ along the spectra of amyloid burden and clinical disease stage
BM Asken, FM Elahi, R La Joie, A Strom, AM Staffaroni, CA Lindbergh, ...
Journal of Alzheimer's Disease 78 (1), 265-276, 2020
702020
Nx-5948, a selective degrader of BTK with activity in preclinical models of hematologic and brain malignancies
DW Robbins, M Noviski, R Rountree, M Tan, N Brathaban, T Ingallinera, ...
Blood 138, 2251, 2021
332021
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127
S Montoya, J Bourcier, M Noviski, H Lu, MC Thompson, A Chirino, J Jahn, ...
Science 383 (6682), eadi5798, 2024
302024
Lower white matter volume and worse executive functioning reflected in higher levels of plasma GFAP among older adults with and without cognitive impairment
BM Asken, L VandeVrede, JC Rojas, C Fonseca, AM Staffaroni, FM Elahi, ...
Journal of the International Neuropsychological Society 28 (6), 588-599, 2022
252022
Kinase dead BTK mutations confer resistance to covalent and noncovalent BTK inhibitors but are susceptible to clinical stage BTK degraders
S Montoya, J Bourcier, MC Thompson, M Noviski, M Tan, E Wang, X Mi, ...
Blood 140 (Supplement 1), 1811-1813, 2022
172022
Discovery and preclinical pharmacology of NX-2127, an orally bioavailable degrader of Bruton’s tyrosine kinase with immunomodulatory activity for the treatment of patients with …
DW Robbins, MA Noviski, YS Tan, ZA Konst, A Kelly, P Auger, ...
Journal of Medicinal Chemistry 67 (4), 2321-2336, 2024
152024
Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans
FM Elahi, D Harvey, M Altendahl, N Brathaban, N Fernandes, ...
Scientific reports 11 (1), 16198, 2021
142021
Plasma glial fibrillary acidic protein levels differ along the spectra of amyloid burden and clinical disease stage
BM Asken, FM Elahi, R La Joie, A Strom, AM Staffaroni, CA Lindbergh, ...
Journal of Alzheimer’s Disease 80 (1), 471-474, 2021
112021
Concurrent degradation of BTK and IMiD neosubstrates by NX-2127 enhances multiple mechanisms of tumor killing
MA Noviski, J Ma, E Lee, N Brathaban, M Tan, L Perez, DW Robbins, ...
Cancer Research 82 (12_Supplement), 1126-1126, 2022
82022
NX-2127: A first-in-class clinical stage degrader of BTK and IKZF1/3 for the treatment of patients with B cell malignancies
JT Mihalic, N Brathaban, B Bravo, T Ingallinera, D Kato, H Lu, J Ma, ...
Cancer Research 83 (7_Supplement), 3423-3423, 2023
42023
NX-5948 promotes selective, sub-nanomolar degradation of inhibitor-resistant BTK mutants
MA Noviski, N Brathaban, R Mukerji, S Yung, J Ye, H Bousquet, ...
Cancer Research 83 (7_Supplement), 2850-2850, 2023
32023
Blood‐brain barrier dysfunction is associated with A/T/N biomarkers and cognition in the aging brain
Y Tabdili, KCD Belmonte, N Brathaban, E Iorio, R Park, AM VandeBunte, ...
Alzheimer's & Dementia 18, e066675, 2022
12022
Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans (vol 11, 16198 …
FM Elahi, D Harvey, M Altendahl, N Brathaban, N Fernandes, ...
SCIENTIFIC REPORTS 12 (1), 2022
12022
Small RNA signatures of acute ischemic stroke in L1CAM positive extracellular vesicles
B Manwani, N Brathaban, A Baqai, Y Munshi, HW Ahnstedt, M Zhang, ...
Scientific Reports 14 (1), 13560, 2024
2024
Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans
FM Elahi, D Harvey, M Altendahl, N Brathaban, N Fernandes, ...
Scientific Reports 12 (1), 2008, 2022
2022
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