Plasma glial fibrillary acidic protein levels differ along the spectra of amyloid burden and clinical disease stage BM Asken, FM Elahi, R La Joie, A Strom, AM Staffaroni, CA Lindbergh, ... Journal of Alzheimer's Disease 78 (1), 265-276, 2020 | 70 | 2020 |
Nx-5948, a selective degrader of BTK with activity in preclinical models of hematologic and brain malignancies DW Robbins, M Noviski, R Rountree, M Tan, N Brathaban, T Ingallinera, ... Blood 138, 2251, 2021 | 33 | 2021 |
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127 S Montoya, J Bourcier, M Noviski, H Lu, MC Thompson, A Chirino, J Jahn, ... Science 383 (6682), eadi5798, 2024 | 30 | 2024 |
Lower white matter volume and worse executive functioning reflected in higher levels of plasma GFAP among older adults with and without cognitive impairment BM Asken, L VandeVrede, JC Rojas, C Fonseca, AM Staffaroni, FM Elahi, ... Journal of the International Neuropsychological Society 28 (6), 588-599, 2022 | 25 | 2022 |
Kinase dead BTK mutations confer resistance to covalent and noncovalent BTK inhibitors but are susceptible to clinical stage BTK degraders S Montoya, J Bourcier, MC Thompson, M Noviski, M Tan, E Wang, X Mi, ... Blood 140 (Supplement 1), 1811-1813, 2022 | 17 | 2022 |
Discovery and preclinical pharmacology of NX-2127, an orally bioavailable degrader of Bruton’s tyrosine kinase with immunomodulatory activity for the treatment of patients with … DW Robbins, MA Noviski, YS Tan, ZA Konst, A Kelly, P Auger, ... Journal of Medicinal Chemistry 67 (4), 2321-2336, 2024 | 15 | 2024 |
Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans FM Elahi, D Harvey, M Altendahl, N Brathaban, N Fernandes, ... Scientific reports 11 (1), 16198, 2021 | 14 | 2021 |
Plasma glial fibrillary acidic protein levels differ along the spectra of amyloid burden and clinical disease stage BM Asken, FM Elahi, R La Joie, A Strom, AM Staffaroni, CA Lindbergh, ... Journal of Alzheimer’s Disease 80 (1), 471-474, 2021 | 11 | 2021 |
Concurrent degradation of BTK and IMiD neosubstrates by NX-2127 enhances multiple mechanisms of tumor killing MA Noviski, J Ma, E Lee, N Brathaban, M Tan, L Perez, DW Robbins, ... Cancer Research 82 (12_Supplement), 1126-1126, 2022 | 8 | 2022 |
NX-2127: A first-in-class clinical stage degrader of BTK and IKZF1/3 for the treatment of patients with B cell malignancies JT Mihalic, N Brathaban, B Bravo, T Ingallinera, D Kato, H Lu, J Ma, ... Cancer Research 83 (7_Supplement), 3423-3423, 2023 | 4 | 2023 |
NX-5948 promotes selective, sub-nanomolar degradation of inhibitor-resistant BTK mutants MA Noviski, N Brathaban, R Mukerji, S Yung, J Ye, H Bousquet, ... Cancer Research 83 (7_Supplement), 2850-2850, 2023 | 3 | 2023 |
Blood‐brain barrier dysfunction is associated with A/T/N biomarkers and cognition in the aging brain Y Tabdili, KCD Belmonte, N Brathaban, E Iorio, R Park, AM VandeBunte, ... Alzheimer's & Dementia 18, e066675, 2022 | 1 | 2022 |
Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans (vol 11, 16198 … FM Elahi, D Harvey, M Altendahl, N Brathaban, N Fernandes, ... SCIENTIFIC REPORTS 12 (1), 2022 | 1 | 2022 |
Small RNA signatures of acute ischemic stroke in L1CAM positive extracellular vesicles B Manwani, N Brathaban, A Baqai, Y Munshi, HW Ahnstedt, M Zhang, ... Scientific Reports 14 (1), 13560, 2024 | | 2024 |
Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans FM Elahi, D Harvey, M Altendahl, N Brathaban, N Fernandes, ... Scientific Reports 12 (1), 2008, 2022 | | 2022 |