Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS SPJ Fancy, SE Baranzini, C Zhao, DI Yuk, KA Irvine, S Kaing, N Sanai, ... Genes & development 23 (13), 1571-1585, 2009 | 659 | 2009 |
Remyelination protects axons from demyelination-associated axon degeneration KA Irvine, WF Blakemore Brain 131 (6), 1464-1477, 2008 | 474 | 2008 |
Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury JL Nielson, J Paquette, AW Liu, CF Guandique, CA Tovar, T Inoue, ... Nature communications 6 (1), 8581, 2015 | 225 | 2015 |
Age increases axon loss associated with primary demyelination in cuprizone-induced demyelination in C57BL/6 mice KA Irvine, WF Blakemore Journal of neuroimmunology 175 (1-2), 69-76, 2006 | 133 | 2006 |
Transplanted oligodendrocyte precursor cells reduce neurodegeneration in a model of glaucoma ND Bull, KA Irvine, RJM Franklin, KR Martin Investigative ophthalmology & visual science 50 (9), 4244-4253, 2009 | 110 | 2009 |
Chronic pain after traumatic brain injury: pathophysiology and pain mechanisms KA Irvine, JD Clark Pain medicine 19 (7), 1315-1333, 2018 | 98 | 2018 |
An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss DW Hampton, J Anderson, G Pryce, KA Irvine, G Giovannoni, JW Fawcett, ... Journal of neuroimmunology 201, 200-211, 2008 | 96 | 2008 |
Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells AJ Joannides, DJ Webber, O Raineteau, C Kelly, KA Irvine, C Watts, ... Brain 130 (5), 1263-1275, 2007 | 83 | 2007 |
Derivation of multivariate syndromic outcome metrics for consistent testing across multiple models of cervical spinal cord injury in rats AR Ferguson, KA Irvine, JC Gensel, JL Nielson, A Lin, J Ly, MR Segal, ... PloS one 8 (3), e59712, 2013 | 73 | 2013 |
A novel method for assessing proximal and distal forelimb function in the rat: the Irvine, Beatties and Bresnahan (IBB) forelimb scale KA Irvine, AR Ferguson, KD Mitchell, SB Beattie, MS Beattie, ... JoVE (Journal of Visualized Experiments), e2246, 2010 | 61 | 2010 |
The Irvine, Beatties, and Bresnahan (IBB) forelimb recovery scale: an assessment of reliability and validity KA Irvine, AR Ferguson, KD Mitchell, SB Beattie, A Lin, ED Stuck, JR Huie, ... Frontiers in neurology 5, 116, 2014 | 58 | 2014 |
Effects of direct transplantation of multipotent mesenchymal stromal/stem cells into the demyelinated spinal cord DPJ Hunt, KA Irvine, DJ Webber, DAS Compston, WF Blakemore, ... Cell transplantation 17 (7), 865-873, 2008 | 56 | 2008 |
Forelimb locomotor assessment scale (FLAS): novel assessment of forelimb dysfunction after cervical spinal cord injury KD Anderson, KG Sharp, M Hofstadter, KA Irvine, M Murray, O Steward Experimental neurology 220 (1), 23-33, 2009 | 51 | 2009 |
Pharmacological characters of oliceridine, a μ-opioid receptor G-protein–biased ligand in mice DY Liang, WW Li, C Nwaneshiudu, KA Irvine, JD Clark Anesthesia & Analgesia 129 (5), 1414-1421, 2019 | 46 | 2019 |
Development of a database for translational spinal cord injury research JL Nielson, CF Guandique, AW Liu, DA Burke, AT Lash, R Moseanko, ... Journal of neurotrauma 31 (21), 1789-1799, 2014 | 46 | 2014 |
A different regional response by mouse oligodendrocyte progenitor cells (OPCs) to high‐dose X‐irradiation has consequences for repopulating OPC‐depleted normal tissue KA Irvine, WF Blakemore European Journal of Neuroscience 25 (2), 417-424, 2007 | 42 | 2007 |
Corticospinal sprouting differs according to spinal injury location and cortical origin in macaque monkeys C Darian-Smith, A Lilak, J Garner, KA Irvine Journal of Neuroscience 34 (37), 12267-12279, 2014 | 38 | 2014 |
Endogenous or exogenous oligodendrocytes for remyelination WF Blakemore, KA Irvine Journal of the neurological sciences 265 (1-2), 43-46, 2008 | 35 | 2008 |
Nociceptive and cognitive changes in a murine model of polytrauma P Sahbaie, M Tajerian, P Yang, KA Irvine, TT Huang, J Luo, T Wyss-Coray, ... The Journal of Pain 19 (12), 1392-1405, 2018 | 30 | 2018 |
Morphine exacerbates postfracture nociceptive sensitization, functional impairment, and microglial activation in mice WW Li, KA Irvine, P Sahbaie, TZ Guo, X Shi, VL Tawfik, WS Kingery, ... Anesthesiology 130 (2), 292-308, 2019 | 28 | 2019 |