PTG-0861: A novel HDAC6-selective inhibitor as a therapeutic strategy in acute myeloid leukaemia JM Gawel, AE Shouksmith, YS Raouf, N Nawar, K Toutah, S Bukhari, ... European Journal of Medicinal Chemistry 201, 112411, 2020 | 40 | 2020 |
ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts AL Yuan, CB Ricks, AK Bohm, X Lun, L Maxwell, S Safdar, S Bukhari, ... PLoS One 13 (8), e0202860, 2018 | 32 | 2018 |
Development of HDAC inhibitors exhibiting therapeutic potential in T-cell prolymphocytic leukemia K Toutah, N Nawar, S Timonen, H Sorger, YS Raouf, S Bukhari, J von Jan, ... Journal of medicinal chemistry 64 (12), 8486-8509, 2021 | 29 | 2021 |
Class I/IIb-selective HDAC inhibitor exhibits oral bioavailability and therapeutic efficacy in acute myeloid leukemia AE Shouksmith, JM Gawel, N Nawar, D Sina, YS Raouf, S Bukhari, L He, ... ACS Medicinal Chemistry Letters 11 (1), 56-64, 2019 | 26 | 2019 |
Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma N Nawar, S Bukhari, AA Adile, Y Suk, P Manaswiyoungkul, K Toutah, ... Journal of medicinal chemistry 65 (4), 3193-3217, 2022 | 20 | 2022 |
Unique molecular interaction with the histone deacetylase 6 catalytic tunnel: crystallographic and biological characterization of a model chemotype OO Olaoye, PR Watson, N Nawar, M Geletu, A Sedighi, S Bukhari, ... Journal of medicinal chemistry 64 (5), 2691-2704, 2021 | 18 | 2021 |
In vitro modeling of glioblastoma initiation using PDGF-AA and p53-null neural progenitors AK Bohm, J DePetro, CE Binding, A Gerber, N Chahley, ND Berger, ... Neuro-oncology 22 (8), 1150-1161, 2020 | 13 | 2020 |
High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lym HK Garcha, N Nawar, H Sorger, F Erdogan, MMK Aung, A Sedighi, ... Pharmaceutics 15 (11)), 2022 | | 2022 |
Characterization and Biological Evaluation of HDAC6 Selective Inhibitors S Bukhari University of Toronto (Canada), 2020 | | 2020 |
Beyond Conventional Models: Recreating the Initiation, Evolution, and Genome of GBM A Bohm, J DePetro, C Binding, A Gerber, N Chahley, M Ware, K Thomas, ... bioRxiv, 837138, 2019 | | 2019 |
TMOD-02. A MODEL OF THE INITIATION AND GENOMIC LANDSCAPE OF GLIOBLASTOMA (GBM) A Bohm, J DePetro, C Binding, C Grisdale, M Ware, S Lawn, N Chahley, ... Neuro-Oncology 21 (Suppl 6), vi262, 2019 | | 2019 |