Predictive compound accumulation rules yield a broad-spectrum antibiotic MF Richter, BS Drown, AP Riley, A Garcia, T Shirai, RL Svec, ... Nature 545 (7654), 299-304, 2017 | 879 | 2017 |
Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analogues AP Riley, CE Groer, D Young, AW Ewald, BM Kivell, TE Prisinzano Journal of medicinal chemistry 57 (24), 10464-10475, 2014 | 113 | 2014 |
Azaphilones Inhibit Tau Aggregation and Dissolve Tau Aggregates in Vitro SR Paranjape, AP Riley, AD Somoza, CE Oakley, CCC Wang, ... ACS chemical neuroscience 6 (5), 751-760, 2015 | 63 | 2015 |
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting μ Opioid Analgesic with Reduced Abuse Liability RS Crowley, AP Riley, AM Sherwood, CE Groer, N Shivaperumal, ... Journal of medicinal chemistry 59 (24), 11027-11038, 2016 | 44 | 2016 |
Isolation and Pharmacological Characterization of Six Opioidergic Picralima nitida Alkaloids SM Creed, AM Gutridge, MD Argade, MR Hennessy, JB Friesen, GF Pauli, ... Journal of natural products 84 (1), 71-80, 2020 | 32 | 2020 |
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Design, Synthesis, and Evaluation of Analogues with Improved Potency and G-protein … RS Crowley, AP Riley, AF Alder, RJ Anderson III, D Luo, S Kaska, ... ACS chemical neuroscience 11 (12), 1781-1790, 2020 | 27 | 2020 |
Holo structure and steady state kinetics of the thiazolinyl imine reductases for siderophore biosynthesis KM Meneely, TA Ronnebaum, AP Riley, TE Prisinzano, AL Lamb Biochemistry 55 (38), 5423-5433, 2016 | 23 | 2016 |
Palladium-Catalyzed Transformations of Salvinorin A, a Neoclerodane Diterpene from Salvia divinorum AP Riley, VW Day, HA Navarro, TE Prisinzano Organic letters 15 (23), 5936-5939, 2013 | 18 | 2013 |
What we have gained from ibogaine: α3β4 nicotinic acetylcholine receptor inhibitors as treatments for substance use disorders CJ Straub, LE Rusali, KM Kremiller, AP Riley Journal of medicinal chemistry 66 (1), 107-121, 2022 | 11 | 2022 |
Synthesis of Aristoquinoline Enantiomers and Their Evaluation at the α3β4 Nicotinic Acetylcholine Receptor MD Argade, CJ Straub, LE Rusali, BD Santarsiero, AP Riley Organic letters 23 (20), 7693-7697, 2021 | 10 | 2021 |
Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism KM Meneely, Q Luo, AP Riley, B Taylor, A Roy, RL Stein, TE Prisinzano, ... Bioorganic & medicinal chemistry 22 (21), 5961-5969, 2014 | 10 | 2014 |
Rational inhibitor design for Pseudomonas aeruginosa salicylate adenylation enzyme PchD CL Shelton, KM Meneely, TA Ronnebaum, AS Chilton, AP Riley, ... JBIC Journal of Biological Inorganic Chemistry 27 (6), 541-551, 2022 | 9 | 2022 |
Topoisomerase inhibitors with antibacterial and anticancer activity PJ Hergenrother, AP Riley US Patent 11,274,106, 2022 | 5 | 2022 |
Modified Akuamma Alkaloids with Increased Potency at the Mu-opioid Receptor MR Hennessy, AM Gutridge, AR French, ES Rhoda, YJ Meqbil, M Gill, ... Journal of medicinal chemistry 66 (5), 3312-3326, 2023 | 4 | 2023 |
Synthesis of α3β4 Nicotinic Acetylcholine Receptor Modulators Derived from Aristoquinoline That Reduce Reinstatement of Cocaine-Seeking Behavior LE Rusali, AM Lopez-Hernandez, KM Kremiller, GC Kulkarni, A Gour, ... Journal of Medicinal Chemistry 67 (1), 529-542, 2023 | 3 | 2023 |
Small molecules active against gram-negative bacteria PJ Hergenrother, M Richter, A Riley, B Drown, M Chavez, S Tasker, ... US Patent 10,995,097, 2021 | 3 | 2021 |
Agonists of the mu opioid receptor TE Prisinzano, AP Riley, CE Groer US Patent 10,125,129, 2018 | 3 | 2018 |
Syntheses of Aristotelia Alkaloids: Reflections in the Chiral Pool MD Argade, AP Riley Synlett 33 (13), 1209-1214, 2022 | 2 | 2022 |
Discovery of Potent Kappa Opioid Receptor Agonists Derived from Akuammicine MR Hennessy, SM Creed, AM Gutridge, LE Rusali, D Luo, B Sepehri, ... Journal of Medicinal Chemistry 67 (23), 20842-20857, 2024 | 1 | 2024 |
Discovery of Antinociceptive α9α10 Nicotinic Acetylcholine Receptor Antagonists by Stable Receptor Expression KM Kremiller, GC Kulkarni, LM Harris, H Gunasekara, Y Kashyap, ... ACS Chemical Biology 19 (11), 2291-2303, 2024 | 1 | 2024 |