ROS and the DNA damage response in cancer US Srinivas, BWQ Tan, BA Vellayappan, AD Jeyasekharan Redox biology 25, 101084, 2019 | 1425 | 2019 |
HP1-β mobilization promotes chromatin changes that initiate the DNA damage response N Ayoub, AD Jeyasekharan, JA Bernal, AR Venkitaraman Nature 453 (7195), 682-686, 2008 | 502 | 2008 |
Biomarkers for homologous recombination deficiency in cancer MM Hoppe, R Sundar, DSP Tan, AD Jeyasekharan JNCI: Journal of the National Cancer Institute 110 (7), 704-713, 2018 | 287 | 2018 |
PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair H Khoury-Haddad, N Guttmann-Raviv, I Ipenberg, D Huggins, ... Proceedings of the National Academy of Sciences 111 (7), E728-E737, 2014 | 146 | 2014 |
The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry N Ayoub, E Rajendra, X Su, AD Jeyasekharan, R Mahen, ... Current Biology 19 (13), 1075-1085, 2009 | 121 | 2009 |
A white light confocal microscope for spectrally resolved multidimensional imaging JH Frank, AD Elder, J Swartling, AR Venkitaraman, AD Jeyasekharan, ... Journal of microscopy 227 (3), 203-215, 2007 | 119 | 2007 |
A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization AD Jeyasekharan, Y Liu, H Hattori, V Pisupati, AB Jonsdottir, E Rajendra, ... Nature structural & molecular biology 20 (10), 1191-1198, 2013 | 113 | 2013 |
Molecular pathogenic pathways in extranodal NK/T cell lymphoma S de Mel, SSS Hue, AD Jeyasekharan, WJ Chng, SB Ng Journal of hematology & oncology 12, 1-18, 2019 | 104 | 2019 |
Epstein-Barr virus-associated primary nodal T/NK-cell lymphoma shows a distinct molecular signature and copy number changes SB Ng, TH Chung, S Kato, S Nakamura, E Takahashi, YH Ko, JD Khoury, ... Haematologica 103 (2), 278, 2018 | 101 | 2018 |
LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition S Nagasawa, AS Sedukhina, Y Nakagawa, I Maeda, M Kubota, ... PloS one 10 (2), e0118002, 2015 | 88 | 2015 |
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation JSY Ho, BWY Mok, L Campisi, T Jordan, S Yildiz, S Parameswaran, ... Cell 184 (10), 2618-2632. e17, 2021 | 86 | 2021 |
Mobilization and recruitment of HP1β: a bimodal response to DNA breakage N Ayoub, AD Jeyasekharan, AR Venkitaraman Cell cycle 8 (18), 2946-2951, 2009 | 83 | 2009 |
A DNA-damage selective role for BRCA1 E3 ligase in claspin ubiquitylation, CHK1 activation, and DNA repair K Sato, E Sundaramoorthy, E Rajendra, H Hattori, AD Jeyasekharan, ... Current biology 22 (18), 1659-1666, 2012 | 73 | 2012 |
A segregated-team model to maintain cancer care during the COVID-19 outbreak at an academic center in Singapore. N Ngoi, J Lim, S Ow, WY Jen, M Lee, W Teo, J Ho, R Sundar, ML Tung, ... Annals of Oncology, 2020 | 60 | 2020 |
A-type lamins maintain the positional stability of DNA damage repair foci in mammalian nuclei R Mahen, H Hattori, M Lee, P Sharma, AD Jeyasekharan, ... PloS one 8 (5), e61893, 2013 | 60 | 2013 |
Choice of PD-L1 immunohistochemistry assay influences clinical eligibility for gastric cancer immunotherapy J Yeong, HYJ Lum, CB Teo, BKJ Tan, YH Chan, RYK Tay, JRE Choo, ... Gastric Cancer 25 (4), 741-750, 2022 | 57 | 2022 |
NF-κB signaling mediates acquired resistance after PARP inhibition Y Nakagawa, AS Sedukhina, N Okamoto, S Nagasawa, N Suzuki, T Ohta, ... Oncotarget 6 (6), 3825, 2015 | 53 | 2015 |
NF-κB signaling mediates acquired resistance after PARP inhibition Y Nakagawa, AS Sedukhina, N Okamoto, S Nagasawa, N Suzuki, T Ohta, ... Oncotarget 6 (6), 3825, 2015 | 53 | 2015 |
Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis R Mahen, AD Jeyasekharan, NP Barry, AR Venkitaraman Proceedings of the National Academy of Sciences 108 (22), 9310-9315, 2011 | 53 | 2011 |
Limb hypothermia for preventing paclitaxel-induced peripheral neuropathy in breast cancer patients: a pilot study R Sundar, A Bandla, SSH Tan, LD Liao, NB Kumarakulasinghe, ... Frontiers in oncology 6, 274, 2017 | 50 | 2017 |