The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44 C Liu, K Kelnar, B Liu, X Chen, T Calhoun-Davis, H Li, L Patrawala, H Yan, ... Nature medicine 17 (2), 211-215, 2011 | 1634 | 2011 |
NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation CR Jeter, B Liu, X Liu, X Chen, C Liu, T Calhoun-Davis, J Repass, ... Oncogene 30 (36), 3833-3845, 2011 | 446 | 2011 |
The PSA−/lo prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration J Qin, X Liu, B Laffin, X Chen, G Choy, CR Jeter, T Calhoun-Davis, H Li, ... Cell stem cell 10 (5), 556-569, 2012 | 359 | 2012 |
Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN M Han, M Liu, Y Wang, X Chen, J Xu, Y Sun, L Zhao, H Qu, Y Fan, C Wu PloS one 7 (6), e39520, 2012 | 289 | 2012 |
PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells H Li, X Chen, T Calhoun-Davis, K Claypool, DG Tang Cancer research 68 (6), 1820-1825, 2008 | 288 | 2008 |
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer D Zhang, D Park, Y Zhong, Y Lu, K Rycaj, S Gong, X Chen, X Liu, ... Nature communications 7 (1), 10798, 2016 | 210 | 2016 |
Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer H Dong, J Hu, K Zou, M Ye, Y Chen, C Wu, X Chen, M Han Molecular cancer 18, 1-18, 2019 | 194 | 2019 |
MiR‐21 regulates epithelial‐mesenchymal transition phenotype and hypoxia‐inducible factor‐1α expression in third‐sphere forming breast cancer stem cell‐like cells M Han, Y Wang, M Liu, X Bi, J Bao, N Zeng, Z Zhu, Z Mo, C Wu, X Chen Cancer science 103 (6), 1058-1064, 2012 | 157 | 2012 |
Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells M Han, M Liu, Y Wang, Z Mo, X Bi, Z Liu, Y Fan, X Chen, C Wu Molecular and cellular biochemistry 363, 427-436, 2012 | 145 | 2012 |
miRNA-128 suppresses prostate cancer by inhibiting BMI-1 to inhibit tumor-initiating cells M Jin, T Zhang, C Liu, MA Badeaux, B Liu, R Liu, C Jeter, X Chen, ... Cancer research 74 (15), 4183-4195, 2014 | 133 | 2014 |
Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses Q Li, Q Deng, HP Chao, X Liu, Y Lu, K Lin, B Liu, GW Tang, D Zhang, ... Nature communications 9 (1), 3600, 2018 | 123 | 2018 |
Long non‐coding RNA SNHG14 induces trastuzumab resistance of breast cancer via regulating PABPC1 expression through H3K27 acetylation H Dong, W Wang, S Mo, Q Liu, X Chen, R Chen, Y Zhang, K Zou, M Ye, ... Journal of cellular and molecular medicine 22 (10), 4935-4947, 2018 | 104 | 2018 |
Cancer stem cells and cell size: A causal link? Q Li, K Rycaj, X Chen, DG Tang Seminars in cancer biology 35, 191-199, 2015 | 102 | 2015 |
New insights into prostate cancer stem cells X Chen, K Rycaj, X Liu, DG Tang Cell cycle 12 (4), 579-586, 2013 | 99 | 2013 |
Defining a population of stem-like human prostate cancer cells that can generate and propagate castration-resistant prostate cancer X Chen, Q Li, X Liu, C Liu, R Liu, K Rycaj, D Zhang, B Liu, C Jeter, ... Clinical Cancer Research 22 (17), 4505-4516, 2016 | 95 | 2016 |
Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells X Liu, X Chen, K Rycaj, HP Chao, Q Deng, C Jeter, C Liu, S Honorio, H Li, ... Oncotarget 6 (27), 23959, 2015 | 75 | 2015 |
Cellular determinants and microenvironmental regulation of prostate cancer metastasis K Rycaj, H Li, J Zhou, X Chen, DG Tang Seminars in cancer biology 44, 83-97, 2017 | 68 | 2017 |
Evidence that senescent human prostate epithelial cells enhance tumorigenicity: cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT B Bhatia, AS Multani, L Patrawala, X Chen, T Calhoun‐Davis, J Zhou, ... International journal of cancer 122 (7), 1483-1495, 2008 | 64 | 2008 |
Drug-Tolerant Cancer Cells Show Reduced Tumor-Initiating Capacity: Depletion of CD44+ Cells and Evidence for Epigenetic Mechanisms H Yan, X Chen, Q Zhang, J Qin, H Li, C Liu, T Calhoun-Davis, LD Coletta, ... PloS one 6 (9), e24397, 2011 | 61 | 2011 |
NANOG reprograms prostate cancer cells to castration resistance via dynamically repressing and engaging the AR/FOXA1 signaling axis CR Jeter, B Liu, Y Lu, HP Chao, D Zhang, X Liu, X Chen, Q Li, K Rycaj, ... Cell Discovery 2 (1), 1-19, 2016 | 51 | 2016 |