Recent advances in the molecular understanding of glioblastoma FE Bleeker, RJ Molenaar, S Leenstra Journal of neuro-oncology 108, 11-27, 2012 | 573 | 2012 |
Wild-type and mutated IDH1/2 enzymes and therapy responses RJ Molenaar, JP Maciejewski, JW Wilmink, CJF van Noorden Oncogene 37 (15), 1949-1960, 2018 | 265 | 2018 |
The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone RJ Molenaar, D Verbaan, S Lamba, C Zanon, JWM Jeuken, ... Neuro-oncology 16 (9), 1263-1273, 2014 | 247 | 2014 |
The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation RJ Molenaar, T Radivoyevitch, JP Maciejewski, CJF van Noorden, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1846 (2), 326-341, 2014 | 230 | 2014 |
Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198 RJ Molenaar, D Botman, MA Smits, VV Hira, SA van Lith, J Stap, ... Cancer research 75 (22), 4790-4802, 2015 | 159 | 2015 |
Risk of hematologic malignancies after radioiodine treatment of well-differentiated thyroid cancer RJ Molenaar, S Sidana, T Radivoyevitch, AS Advani, AT Gerds, ... Journal of Clinic al Oncology 76, 410, 2017 | 140 | 2017 |
Clinical and biological implications of ancestral and non-ancestral IDH1 and IDH2 mutations in myeloid neoplasms RJ Molenaar, S Thota, Y Nagata, B Patel, M Clemente, B Przychodzen, ... Leukemia 29 (11), 2134-2142, 2015 | 105 | 2015 |
IDH1/2 Mutations Sensitize Acute Myeloid Leukemia to PARP Inhibition and This Is Reversed by IDH1/2-Mutant Inhibitors RJ Molenaar, T Radivoyevitch, Y Nagata, M Khurshed, B Przychodzen, ... Clinical Cancer Research 24 (7), 1705-1715, 2018 | 103 | 2018 |
CD133+ and Nestin+ Glioma Stem-Like Cells Reside Around CD31+ Arterioles in Niches that Express SDF-1α, CXCR4, Osteopontin and Cathepsin K VVV Hira, KJ Ploegmakers, F Grevers, U Verbovšek, C Silvestre-Roig, ... Journal of Histochemistry & Cytochemistry 63 (7), 481-493, 2015 | 99 | 2015 |
Defining AML and MDS second cancer risk dynamics after diagnoses of first cancers treated or not with radiation T Radivoyevitch, RK Sachs, RP Gale, RJ Molenaar, DJ Brenner, BT Hill, ... Leukemia 30 (2), 285-294, 2016 | 95 | 2016 |
Study protocol of a phase IB/II clinical trial of metformin and chloroquine in patients with IDH1-mutated or IDH2-mutated solid tumours RJ Molenaar, RJS Coelen, M Khurshed, E Roos, MWA Caan, ... BMJ open 7 (6), e014961, 2017 | 83 | 2017 |
Mutational profiling of kinases in glioblastoma BA Bleeker FE, Lamba S, Zanon C, Molenaar RJ, Hulsebos TJ, Troost D, van ... BMC Cancer 14, 718, 2014 | 81* | 2014 |
Ion channels in glioblastoma RJ Molenaar International Scholarly Research Notices 2011 (1), 590249, 2011 | 80 | 2011 |
In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma M Khurshed, RJ Molenaar, K Lenting, WP Leenders, CJF van Noorden Oncotarget 8 (30), 49165, 2017 | 73 | 2017 |
The hypoxic peri-arteriolar glioma stem cell niche, an integrated concept of five types of niches in human glioblastoma DA Aderetti, VVV Hira, RJ Molenaar, CJF van Noorden Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1869 (2), 346-354, 2018 | 69 | 2018 |
Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers? SAM van Lith, AC Navis, K Verrijp, SP Niclou, R Bjerkvig, P Wesseling, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1846 (1), 66-74, 2014 | 60 | 2014 |
Risk of acute myeloid leukemia and myelodysplastic syndrome after autotransplants for lymphomas and plasma cell myeloma T Radivoyevitch, RM Dean, BE Shaw, R Brazauskas, HR Tecca, ... Leukemia research 74, 130-136, 2018 | 59 | 2018 |
Phase II Feasibility and biomarker study of neoadjuvant trastuzumab and pertuzumab with chemoradiotherapy for resectable human epidermal growth factor receptor 2–positive … CI Stroes, S Schokker, A Creemers, RJ Molenaar, MCCM Hulshof, ... Journal of Clinical Oncology 38 (5), 462-471, 2020 | 57 | 2020 |
Novel therapeutic strategies to target leukemic cells that hijack compartmentalized continuous hematopoietic stem cell niches VVV Hira, CJF Van Noorden, HE Carraway, JP Maciejewski, RJ Molenaar Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1868 (1), 183-198, 2017 | 55 | 2017 |
Comparison of different methodologies and cryostat versus paraffin sections for chromogenic immunohistochemistry VVV Hira, AL de Jong, K Ferro, M Khurshed, RJ Molenaar, ... Acta histochemica 121 (2), 125-134, 2019 | 49 | 2019 |