关注
Kyra Thrush
Kyra Thrush
未知所在单位机构
在 yale.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking
AT Higgins-Chen, KL Thrush, Y Wang, CJ Minteer, PL Kuo, M Wang, ...
Nature aging 2 (7), 644-661, 2022
1692022
Underlying features of epigenetic aging clocks in vivo and in vitro
Z Liu, D Leung, K Thrush, W Zhao, S Ratliff, T Tanaka, LL Schmitz, ...
Aging cell 19 (10), e13229, 2020
1512020
Aging biomarkers and the brain
AT Higgins-Chen, KL Thrush, ME Levine
Seminars in cell & developmental biology 116, 180-193, 2021
482021
A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin
M Levine, RA McDevitt, M Meer, K Perdue, A Di Francesco, T Meade, ...
Elife 9, e59201, 2020
442020
HCN, formamidic acid, and formamide in aqueous solution: a free-energy map
J Kua, KL Thrush
The Journal of Physical Chemistry B 120 (33), 8175-8185, 2016
362016
Clock work: Deconstructing the epigenetic clock signals in aging, disease, and reprogramming
ME Levine, A Higgins-Chen, K Thrush, C Minteer, P Niimi
BioRxiv, 2022.02. 13.480245, 2022
322022
Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer’s disease
KL Thrush, DA Bennett, C Gaiteri, S Horvath, CH van Dyck, ...
Aging 14 (14), 5641-5668, 2022
152022
R methylCIPHER: a methylation clock investigational package for hypothesis-driven evaluation & research
KL Thrush, AT Higgins-Chen, Z Liu, ME Levine
biorxiv, 2022.07. 13.499978, 2022
152022
More than bad luck: cancer and aging are linked to replication-driven changes to the epigenome
CJ Minteer, K Thrush, J Gonzalez, P Niimi, M Rozenblit, J Rozowsky, J Liu, ...
Science Advances 9 (29), eadf4163, 2023
82023
A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking. Nature Aging, 2 (7), 644–661
AT Higgins‑Chen, KL Thrush, Y Wang, CJ Minteer, P Kuo, M Wang, ...
52022
A computational solution for bolstering reliability of epigenetic clocks: implications for clinical trials and longitudinal tracking. bioRxiv. 2021: 2021.04. 16.440205
AT Higgins-Chen, KL Thrush, Y Wang, PL Kuo, M Wang, CJ Minteer, ...
52021
A Computational solution to bolster epigenetic clock reliability for clinical trials and longitudinal tracking
A Higgins-Chen, K Thrush, T Hu-Seliger, Y Wang, S Hagg, M Levine
Innovation in Aging 5 (Suppl 1), 5, 2021
52021
Reactions of Glycolonitrile with Ammonia and Water: A Free Energy Map
KL Thrush, J Kua
The Journal of Physical Chemistry A 122 (33), 6769-6779, 2018
52018
Revisiting the bad luck hypothesis: Cancer risk and aging are linked to replication-driven changes to the epigenome
CJ Minteer, K Thrush, P Niimi, J Rozowsky, J Liu, M Frank, T McCabe, ...
bioRxiv, 2022.09. 14.507975, 2022
22022
Epigenetic Age Acceleration as a Risk Predictor of Hepatocellular Carcinoma
A Luna, K Thrush
The FASEB Journal 36, 2022
12022
Age-Invariant Genes: Multi-Tissue Identification and Characterization of Murine Reference Genes
JT González, K Thrush, M Meer, ME Levine, AT Higgins-Chen
bioRxiv, 2024
2024
Capturing DNA methylation heterogeneity and examining its relationship to somatic mutations in Alzheimer’s disease
Y Markov, K Thrush, A Higgins‐Chen, L Morgan
Alzheimer's & Dementia 18, e069183, 2022
2022
PCBrainAge: A Brain‐Specific AD‐Associated DNA Methylation Clock
K Thrush, Y Markov, A Higgins‐Chen, L Morgan
Alzheimer's & Dementia 18, e069230, 2022
2022
A Peak Through the Noise: Capturing Biological Heterogeneity in Aging with Our Machine Learning Toolkit
K Thrush
Yale University, 2022
2022
Deep Learning Methods Capture Non-Linear Brain Aging Patterns Underlying Alzheimer’s Disease and Resilience
K Thrush, A Higgins-Chen, Y Markov, R Sehgal, M Levine
Innovation in Aging 5 (Suppl 1), 370, 2021
2021
系统目前无法执行此操作,请稍后再试。
文章 1–20