| Autophagy and neurodegeneration: pathogenic mechanisms and therapeutic opportunities FM Menzies, A Fleming, A Caricasole, CF Bento, SP Andrews, ... Neuron 93 (5), 1015-1034, 2017 | 1095 | 2017 |
| Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain A Caricasole, A Copani, F Caraci, E Aronica, AJ Rozemuller, A Caruso, ... Journal of Neuroscience 24 (26), 6021-6027, 2004 | 486 | 2004 |
| BLUEPRINT to decode the epigenetic signature written in blood D Adams, L Altucci, SE Antonarakis, J Ballesteros, S Beck, A Bird, C Bock, ... Nature biotechnology 30 (3), 224-226, 2012 | 384 | 2012 |
| RNA binding by the Wilms tumor suppressor zinc finger proteins. A Caricasole, A Duarte, SH Larsson, ND Hastie, M Little, G Holmes, ... Proceedings of the National Academy of Sciences 93 (15), 7562-7566, 1996 | 269 | 1996 |
| The Wnt pathway, cell-cycle activation and β-amyloid: novel therapeutic strategies in Alzheimer's disease? A Caricasole, A Copani, A Caruso, F Caraci, L Iacovelli, MA Sortino, ... Trends in pharmacological sciences 24 (5), 233-238, 2003 | 191 | 2003 |
| Increased Dickkopf‐1 expression in transgenic mouse models of neurodegenerative disease MC Rosi, I Luccarini, C Grossi, A Fiorentini, MG Spillantini, A Prisco, ... Journal of neurochemistry 112 (6), 1539-1551, 2010 | 188 | 2010 |
| Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is required for the development of ischemic neuronal death I Cappuccio, A Calderone, CL Busceti, F Biagioni, F Pontarelli, V Bruno, ... Journal of Neuroscience 25 (10), 2647-2657, 2005 | 179 | 2005 |
| Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5· LRP6 receptor complex and modulation by Dickkopf proteins A Caricasole, T Ferraro, L Iacovelli, E Barletta, A Caruso, D Melchiorri, ... Journal of Biological Chemistry 278 (39), 37024-37031, 2003 | 175 | 2003 |
| Native group‐III metabotropic glutamate receptors are coupled to the mitogen‐activated protein kinase/phosphatidylinositol‐3‐kinase pathways L Iacovelli, V Bruno, L Salvatore, D Melchiorri, R Gradini, A Caricasole, ... Journal of neurochemistry 82 (2), 216-223, 2002 | 150 | 2002 |
| A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease MR Smith, A Syed, T Lukacsovich, J Purcell, BA Barbaro, SA Worthge, ... Human molecular genetics 23 (11), 2995-3007, 2014 | 149 | 2014 |
| Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1 C Scali, F Caraci, M Gianfriddo, E Diodato, R Roncarati, G Pollio, ... Neurobiology of disease 24 (2), 254-265, 2006 | 146 | 2006 |
| Induction of the Wnt antagonist, Dickkopf-1, contributes to the development of neuronal death in models of brain focal ischemia F Mastroiacovo, CL Busceti, F Biagioni, SG Moyanova, MH Meisler, ... Journal of Cerebral Blood Flow & Metabolism 29 (2), 264-276, 2009 | 141 | 2009 |
| L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors S Chiechio, A Caricasole, E Barletta, M Storto, MV Catania, A Copani, ... Molecular pharmacology 61 (5), 989-996, 2002 | 134 | 2002 |
| Induction of the Wnt inhibitor, Dickkopf‐1, is associated with neurodegeneration related to temporal lobe epilepsy CL Busceti, F Biagioni, E Aronica, B Riozzi, M Storto, G Battaglia, ... Epilepsia 48 (4), 694-705, 2007 | 121 | 2007 |
| Human growth-differentiation factor 3 (hGDF3): developmental regulation in human teratocarcinoma cell lines and expression in primary testicular germ cell tumours AAD Caricasole, RHN van Schaik, LM Zeinstra, CDJ Wierikx, ... Oncogene 16 (1), 95-103, 1998 | 119 | 1998 |
| Comparative study of naturally occurring huntingtin fragments in Drosophila points to exon 1 as the most pathogenic species in Huntington's disease BA Barbaro, T Lukacsovich, N Agrawal, J Burke, DJ Bornemann, ... Human molecular genetics 24 (4), 913-925, 2015 | 107 | 2015 |
| Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells A Caruso, M Motolese, L Iacovelli, F Caraci, A Copani, F Nicoletti, ... Journal of neurochemistry 98 (2), 364-371, 2006 | 103 | 2006 |
| β-Amyloid-induced synthesis of the ganglioside GD3 is a requisite for cell cycle reactivation and apoptosis in neurons A Copani, D Melchiorri, A Caricasole, F Martini, P Sale, R Carnevale, ... Journal of Neuroscience 22 (10), 3963-3968, 2002 | 102 | 2002 |
| Two sides of the same coin: Wnt signaling in neurodegeneration and neuro-oncology A Caricasole, A Bakker, A Copani, F Nicoletti, G Gaviraghi, ... Bioscience reports 25 (5-6), 309-327, 2005 | 100 | 2005 |
| siRNA screen identifies QPCT as a druggable target for Huntington's disease M Jimenez-Sanchez, W Lam, M Hannus, B Sönnichsen, S Imarisio, ... Nature chemical biology 11 (5), 347-354, 2015 | 92 | 2015 |
