| Isoforms of MUC16 activate oncogenic signaling through EGF receptors to enhance the progression of pancreatic cancer D Thomas, S Sagar, X Liu, HR Lee, JA Grunkemeyer, PM Grandgenett, ... Molecular Therapy 29 (4), 1557-1571, 2021 | 58 | 2021 |
| Truncated O‐glycans promote epithelial‐to‐mesenchymal transition and stemness properties of pancreatic cancer cells D Thomas, S Sagar, T Caffrey, PM Grandgenett, P Radhakrishnan Journal of cellular and molecular medicine 23 (10), 6885-6896, 2019 | 42 | 2019 |
| MUC4 enhances gemcitabine resistance and malignant behaviour in pancreatic cancer cells expressing cancer-associated short O-glycans S Sagar, PD Leiphrakpam, D Thomas, KL McAndrews, TC Caffrey, ... Cancer letters 503, 91-102, 2021 | 36 | 2021 |
| Bromelain inhibits SARS‐CoV‐2 infection via targeting ACE‐2, TMPRSS2, and spike protein S Sagar, AK Rathinavel, WE Lutz, LR Struble, S Khurana, AT Schnaubelt, ... Clinical and translational medicine 11 (2), 2021 | 28 | 2021 |
| Effects of CEES and LPS synergistically stimulate oxidative stress inactivates OGG1 signaling in macrophage cells S Sagar, P Kumar, RR Behera, A Pal Journal of hazardous materials 278, 236-249, 2014 | 24 | 2014 |
| Bromelain inhibits SARS-CoV-2 infection in VeroE6 cells S Sagar, AK Rathinavel, WE Lutz, LR Struble, S Khurana, AT Schnaubelt, ... Biorxiv, 2020 | 23 | 2020 |
| A polymeric nanogel-based treatment regimen for enhanced efficacy and sequential administration of synergistic drug combination in pancreatic cancer KS Soni, D Thomas, T Caffrey, K Mehla, F Lei, KA O’Connell, S Sagar, ... Journal of Pharmacology and Experimental Therapeutics 370 (3), 894-901, 2019 | 21 | 2019 |
| Increasing NO level regulates apoptosis and inflammation in macrophages after 2-chloroethyl ethyl sulphide challenge S Sagar, SR Parida, S Sabnam, H Rizwan, S Pal, MM Swain, A Pal The International Journal of Biochemistry & Cell Biology 83, 1-14, 2017 | 20 | 2017 |
| The glycoprotein mucin‐1 negatively regulates GalNAc transferase 5 expression in pancreatic cancer T Caffrey, S Sagar, D Thomas, ME Lewallen, MA Hollingsworth, ... FEBS letters 593 (19), 2751-2761, 2019 | 17 | 2019 |
| Insect cell expression and purification of recombinant SARS‐COV‐2 spike proteins that demonstrate ACE2 binding LR Struble, AL Smith, WE Lutz, G Grubbs, S Sagar, KW Bayles, ... Protein Science 31 (5), e4300, 2022 | 15 | 2022 |
| Truncated O-Glycan-Bearing MUC16 enhances pancreatic cancer cells aggressiveness via α4β1 integrin complexes and FAK signaling C Rajesh, S Sagar, AK Rathinavel, DT Chemparathy, XL Peng, JJ Yeh, ... International journal of molecular sciences 23 (10), 5459, 2022 | 13 | 2022 |
| Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy S Sagar, S Singh, JR Mallareddy, YA Sonawane, JV Napoleon, S Rana, ... European journal of medicinal chemistry 222, 113579, 2021 | 11 | 2021 |
| Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth JV Napoleon, S Sagar, SP Kubica, L Boghean, S Kour, HM King, ... Proceedings of the National Academy of Sciences 119 (18), e2115071119, 2022 | 7 | 2022 |
| Targeting Oxidative Stress Specific NRF2 In Pancreatic Cancer Stem Cells S Sagar, C Rajesh, P Radhakrishnan Handbook of Oxidative Stress in Cancer: Therapeutic Aspects, 1-21, 2022 | 1 | 2022 |
| Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9. 6 EN Aguilar, S Sagar, BR Murray, C Rajesh, EK Lei, SA Michaud, ... Molecular Cancer Therapeutics 23 (6), 836-853, 2024 | | 2024 |
| Role of Truncated O-glycans in Pancreatic Cancer Progression and Metastasis S Sagar, Y Matsumoto, S Suttapitugsakul, MA Hollingsworth, ... GLYCOBIOLOGY 33 (11), 1032-1032, 2023 | | 2023 |
| 169 Immunotherapeutic potential of the humanized anti-MUC16 antibody AR9. 6 against PDAC C Rajesh, S Sagar, C Brooks, M Hollingsworth, P Radhakrishnan Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
| LPS infection augmented ROS accumulation regulates inflammation and apoptosis via Erk1/2MAPK/Akt/NF-κB pathways in keratinocytes after 2-chloroethyl ethyl sulphide challenge S Sagar, G Kumari, SR Parida, A Pal | | 2022 |
| Effect of MUC16 Blockade using the Humanized AR9. 6 Antibody in Patient Derived Organoid Models of PDAC JN Muirhead, S Sagar, C Rajesh, A Black, P Radhakrishnan | | 2022 |
| Mutant K-Ras Mediated Oxidative Stress in Pancreatic Cancer D Thomas, S Sagar, T Caffrey, P Radhakrishnan Handbook of Oxidative Stress in Cancer: Mechanistic Aspects, 1-11, 2021 | | 2021 |
