| Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation MKF Ma, EYT Lau, DHW Leung, J Lo, NPY Ho, LKW Cheng, S Ma, CH Lin, ... Journal of hepatology 67 (5), 979-990, 2017 | 141 | 2017 |
| IRAK1 augments cancer stemness and drug resistance via the AP-1/AKR1B10 signaling cascade in hepatocellular carcinoma BY Cheng, EY Lau, HW Leung, CON Leung, NP Ho, S Gurung, LK Cheng, ... Cancer research 78 (9), 2332-2342, 2018 | 102 | 2018 |
| EPHB2 activates β-catenin to enhance cancer stem cell properties and drive sorafenib resistance in hepatocellular carcinoma HW Leung, CON Leung, EY Lau, KPS Chung, EH Mok, MML Lei, ... Cancer research 81 (12), 3229-3240, 2021 | 79 | 2021 |
| Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine FW Pun, GHD Leung, HW Leung, BHM Liu, X Long, IV Ozerov, J Wang, ... Aging (Albany NY) 14 (6), 2475, 2022 | 46 | 2022 |
| NRF2/SHH signaling cascade promotes tumor-initiating cell lineage and drug resistance in hepatocellular carcinoma HW Leung, EYT Lau, CON Leung, MML Lei, EHK Mok, VW San Ma, ... Cancer letters 476, 48-56, 2020 | 46 | 2020 |
| Identification of therapeutic targets for amyotrophic lateral sclerosis using PandaOmics–an AI-enabled biological target discovery platform FW Pun, BHM Liu, X Long, HW Leung, GHD Leung, QT Mewborne, J Gao, ... Frontiers in aging neuroscience 14, 914017, 2022 | 42 | 2022 |
| Caspase-3–induced activation of SREBP2 drives drug resistance via promotion of cholesterol biosynthesis in hepatocellular carcinoma EHK Mok, CON Leung, L Zhou, MML Lei, HW Leung, M Tong, TL Wong, ... Cancer Research 82 (17), 3102-3115, 2022 | 40 | 2022 |
| Anti-angiogenesis and immunomodulatory activities of an anti-tumor sesquiterpene bigelovin isolated from Inula helianthus-aquatica GGL Yue, BCL Chan, HF Kwok, YL Wong, HW Leung, CJ Ji, KP Fung, ... European journal of medicinal chemistry 59, 243-252, 2013 | 38 | 2013 |
| Novel PI3K/AKT targeting anti-angiogenic activities of 4-vinylphenol, a new therapeutic potential of a well-known styrene metabolite GGL Yue, JKM Lee, HF Kwok, L Cheng, ECW Wong, L Jiang, H Yu, ... Scientific reports 5 (1), 11149, 2015 | 36 | 2015 |
| RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation HW Leung, SM Zhao, GGL Yue, JKM Lee, KP Fung, PC Leung, NH Tan, ... Scientific reports 5 (1), 16985, 2015 | 32 | 2015 |
| Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-κB signaling pathways HW Leung, Z Wang, GGL Yue, SM Zhao, JKM Lee, KP Fung, PC Leung, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (8), 1827-1840, 2015 | 31 | 2015 |
| The interplay of UBE2T and Mule in regulating Wnt/β-catenin activation to promote hepatocellular carcinoma progression NPY Ho, CON Leung, TL Wong, EYT Lau, MML Lei, EHK Mok, HW Leung, ... Cell death & disease 12 (2), 148, 2021 | 29 | 2021 |
| The natural agent 4-vinylphenol targets metastasis and stemness features in breast cancer stem-like cells HW Leung, CH Ko, GGL Yue, I Herr, CBS Lau Cancer chemotherapy and pharmacology 82, 185-197, 2018 | 17 | 2018 |
| Evaluation of the safety profiles of estrogenic Chinese herbal medicines in breast cancer GGL Yue, LS Wong, HW Leung, S Gao, JYS Tsang, ZX Lin, GMK Tse, ... Phytomedicine 56, 103-117, 2019 | 15 | 2019 |
| Is Danggui safe to be taken by breast cancer patients?—a skepticism finally answered by comprehensive preclinical evidence GGL Yue, LS Wong, HW Leung, S Gao, JYS Tsang, ZX Lin, BKB Law, ... Frontiers in pharmacology 10, 706, 2019 | 9 | 2019 |
| Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery A Urban, D Sidorenko, D Zagirova, E Kozlova, A Kalashnikov, S Pushkov, ... Aging (Albany NY) 15 (11), 4649, 2023 | 8 | 2023 |
| A comprehensive AI‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging FW Pun, GHD Leung, HW Leung, J Rice, T Schmauck‐Medina, S Lautrup, ... Aging Cell 22 (12), e14017, 2023 | 6 | 2023 |
| Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics-an AI-enabled biological target discovery platform A Olsen, Z Harpaz, C Ren, A Shneyderman, A Veviorskiy, M Dralkina, ... Aging (Albany NY) 15 (8), 2863, 2023 | 3 | 2023 |
| Pilot study on peptide purity-glycated hexapeptide of HbA1c RD Josephs, Q Liu, G Martos, M Bedu, A Daireaux, T Choteau, ... Metrologia 59 (1A), 08007, 2022 | 2 | 2022 |
| Key comparison study on peptide purity-hexapeptide of HbA0 RD Josephs, Q Liu, G Martos, M Bedu, A Daireaux, T Choteau, ... Metrologia 59 (1A), 08013, 2022 | 1 | 2022 |
