The octarepeat domain of the prion protein binds Cu (II) with three distinct coordination modes at pH 7.4 M Chattopadhyay, ED Walter, DJ Newell, PJ Jackson, E Aronoff-Spencer, ... Journal of the American Chemical Society 127 (36), 12647-12656, 2005 | 269 | 2005 |
Initiation and elongation in fibrillation of ALS-linked superoxide dismutase M Chattopadhyay, A Durazo, SH Sohn, CD Strong, EB Gralla, ... Proceedings of the National Academy of Sciences 105 (48), 18663-18668, 2008 | 267 | 2008 |
Aggregation of copper–zinc superoxide dismutase in familial and sporadic ALS M Chattopadhyay, JS Valentine Antioxidants & redox signaling 11 (7), 1603-1614, 2009 | 213 | 2009 |
IL-17A is increased in the serum and in spinal cord CD8 and mast cells of ALS patients M Fiala, M Chattopadhay, A La Cava, E Tse, G Liu, E Lourenco, A Eskin, ... J Neuroinflammation 7, 76, 2010 | 194 | 2010 |
The affinity of copper binding to the prion protein octarepeat domain: evidence for negative cooperativity ED Walter, M Chattopadhyay, GL Millhauser Biochemistry 45 (43), 13083-13092, 2006 | 168 | 2006 |
Copper and zinc metallation status of copper-zinc superoxide dismutase from amyotrophic lateral sclerosis transgenic mice HL Lelie, A Liba, MW Bourassa, M Chattopadhyay, PK Chan, EB Gralla, ... Journal of Biological Chemistry 286 (4), 2795-2806, 2011 | 154 | 2011 |
SOD1 aggregation and ALS: role of metallation states and disulfide status. Y Sheng, M Chattopadhyay, J Whitelegge, JS Valentine. Curr Top Med Chem, 2013 | 129 | 2013 |
Neuronal phagocytosis by inflammatory macrophages in ALS spinal cord: inhibition of inflammation by resolvin D1 G Liu, M Fiala, MT Mizwicki, J Sayre, L Magpantay, A Siani, M Mahanian, ... American journal of neurodegenerative disease 1 (1), 60, 2012 | 95 | 2012 |
Tocilizumab attenuates inflammation in ALS patients through inhibition of IL6 receptor signaling MT Mizwicki, M Fiala, L Magpantay, N Aziz, J Sayre, G Liu, A Siani, ... American journal of neurodegenerative disease 1 (3), 305, 2012 | 85 | 2012 |
Electron spin relaxation of copper (II) complexes in glassy solution between 10 and 120 K AJ Fielding, S Fox, GL Millhauser, M Chattopadhyay, PMH Kroneck, ... Journal of Magnetic Resonance 179 (1), 92-104, 2006 | 68 | 2006 |
The disulfide bond, but not zinc or dimerization, controls initiation and seeded growth in amyotrophic lateral sclerosis-linked Cu, Zn superoxide dismutase (SOD1) fibrillation M Chattopadhyay, E Nwadibia, CD Strong, EB Gralla, JS Valentine, ... Journal of Biological Chemistry 290 (51), 30624-30636, 2015 | 63 | 2015 |
Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy PK Chan, M Chattopadhyay, S Sharma, P Souda, EB Gralla, DR Borchelt, ... Proceedings of the National Academy of Sciences 110 (27), 10934-10939, 2013 | 59 | 2013 |
Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded β-barrel at physiological temperature A Durazo, BF Shaw, M Chattopadhyay, KF Faull, AM Nersissian, ... Journal of Biological Chemistry 284 (49), 34382-34389, 2009 | 49 | 2009 |
Probing the role of PrP repeats in conformational conversion and amyloid assembly of chimeric yeast prions J Dong, JD Bloom, V Goncharov, M Chattopadhyay, GL Millhauser, ... Journal of Biological Chemistry 282 (47), 34204-34212, 2007 | 43 | 2007 |
Nanoengineered analytical immobilized metal affinity chromatography stationary phase by atom transfer radical polymerization: Separation of synthetic prion peptides P McCarthy, M Chattopadhyay, GL Millhauser, NV Tsarevsky, ... Analytical biochemistry 366 (1), 1-8, 2007 | 38 | 2007 |
VE-1902—A direct thrombin inhibitor with reversible covalent mechanism of action shows efficacy with reduced bleeding in rodent models of thrombosis M Sivaraja, DM Clemens, S Sizikov, S Dash, C Xu, M Rienzo, B Yang, ... Thrombosis research 190, 112-121, 2020 | 8 | 2020 |
Metal-free superoxide dismutase-1 and three different ALS variants share a similar partially unfolded {beta}-barrel at physiological temperature A Durazo, BF Shaw, M Chattopadhyay, KF Faull, AM Nersissian, ... J Biol Chem 284, 34382-34389, 2009 | 5 | 2009 |
Copper and Zinc Metallation Status of Copper Zinc Superoxide Dismutase form Amyotrophic Lateral Sclerosis Transgenic Mice HL Lelie, L Miller, A Liba, MW Bourassa, M Chattopadhyay, PK Chan, ... The Journal of Biological Chemistry 286 (BNL-94908-2011-JA), 2010 | 1 | 2010 |
Abstract TMP98: A New Class of Precision Oral Anticoagulants (proacs) That Mostly Preserves Platelet Activity in vitro and in vivo M Sivaraja, D Clemens, S Sizikov, C Xu, B Yang, L Igoudin, ... Stroke 50 (Suppl_1), ATMP98-ATMP98, 2019 | | 2019 |
Potent cell cycle inhibitors suitable for treatment of multidrug-resistant tumors M Sivaraja, S Sizikov, N Sirisoma, T Kirtadze, M Chattopadhyay, M Ewald, ... Cancer Research 78 (13_Supplement), 4851-4851, 2018 | | 2018 |