| IPS-1, an adaptor triggering RIG-I-and Mda5-mediated type I interferon induction T Kawai, K Takahashi, S Sato, C Coban, H Kumar, H Kato, KJ Ishii, ... Nature immunology 6 (10), 981-988, 2005 | 3111 | 2005 |
| Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6 T Kawai, S Sato, KJ Ishii, C Coban, H Hemmi, M Yamamoto, K Terai, ... Nature immunology 5 (10), 1061-1068, 2004 | 1317 | 2004 |
| A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA KJ Ishii, C Coban, H Kato, K Takahashi, Y Torii, F Takeshita, H Ludwig, ... Nature immunology 7 (1), 40-48, 2006 | 966 | 2006 |
| Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin C Coban, KJ Ishii, T Kawai, H Hemmi, S Sato, S Uematsu, M Yamamoto, ... The Journal of experimental medicine 201 (1), 19-25, 2005 | 834 | 2005 |
| TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines KJ Ishii, T Kawagoe, S Koyama, K Matsui, H Kumar, T Kawai, S Uematsu, ... Nature 451 (7179), 725-729, 2008 | 747 | 2008 |
| Host innate immune receptors and beyond: making sense of microbial infections KJ Ishii, S Koyama, A Nakagawa, C Coban, S Akira Cell host & microbe 3 (6), 352-363, 2008 | 643 | 2008 |
| Essential role of IPS-1 in innate immune responses against RNA viruses H Kumar, T Kawai, H Kato, S Sato, K Takahashi, C Coban, M Yamamoto, ... The Journal of experimental medicine 203 (7), 1795-1803, 2006 | 633 | 2006 |
| Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR) 7-and TLR9-mediated interferon-α induction S Uematsu, S Sato, M Yamamoto, T Hirotani, H Kato, F Takeshita, ... The Journal of experimental medicine 201 (6), 915-923, 2005 | 626 | 2005 |
| DNA released from dying host cells mediates aluminum adjuvant activity T Marichal, K Ohata, D Bedoret, C Mesnil, C Sabatel, K Kobiyama, ... Nature medicine 17 (8), 996-1002, 2011 | 620 | 2011 |
| Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells S Uematsu, MH Jang, N Chevrier, Z Guo, Y Kumagai, M Yamamoto, ... Nature immunology 7 (8), 868-874, 2006 | 558 | 2006 |
| Innate immune response to viral infection S Koyama, KJ Ishii, C Coban, S Akira Cytokine 43 (3), 336-341, 2008 | 541 | 2008 |
| Differential role of TLR-and RLR-signaling in the immune responses to influenza A virus infection and vaccination S Koyama, KJ Ishii, H Kumar, T Tanimoto, C Coban, S Uematsu, T Kawai, ... The Journal of Immunology 179 (7), 4711-4720, 2007 | 377 | 2007 |
| Genomic DNA released by dying cells induces the maturation of APCs KJ Ishii, K Suzuki, C Coban, F Takeshita, Y Itoh, H Matoba, LD Kohn, ... The Journal of Immunology 167 (5), 2602-2607, 2001 | 304 | 2001 |
| Repeated administration of synthetic oligodeoxynucleotides expressing CpG motifs provides long-term protection against bacterial infection DM Klinman, J Conover, C Coban Infection and immunity 67 (11), 5658-5663, 1999 | 232 | 1999 |
| Silica crystals and aluminum salts regulate the production of prostaglandin in macrophages via NALP3 inflammasome-independent mechanisms E Kuroda, KJ Ishii, S Uematsu, K Ohata, C Coban, S Akira, K Aritake, ... Immunity 34 (4), 514-526, 2011 | 231 | 2011 |
| Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involves malarial hemozoin and host TLR9 C Coban, Y Igari, M Yagi, T Reimer, S Koyama, T Aoshi, K Ohata, ... Cell host & microbe 7 (1), 50-61, 2010 | 222 | 2010 |
| Pathological role of Toll-like receptor signaling in cerebral malaria C Coban, KJ Ishii, S Uematsu, N Arisue, S Sato, M Yamamoto, T Kawai, ... International immunology 19 (1), 67-79, 2007 | 216 | 2007 |
| A distinct subpopulation of CD25− T-follicular regulatory cells localizes in the germinal centers JB Wing, Y Kitagawa, M Locci, H Hume, C Tay, T Morita, Y Kidani, ... Proceedings of the National Academy of Sciences 114 (31), E6400-E6409, 2017 | 199 | 2017 |
| Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes S Koyama, T Aoshi, T Tanimoto, Y Kumagai, K Kobiyama, T Tougan, ... Science translational medicine 2 (25), 25ra24-25ra24, 2010 | 152 | 2010 |
| Novel strategies to improve DNA vaccine immunogenicity C Coban, K Kobiyama, T Aoshi, F Takeshita, T Horii, S Akira, K J Ishii Current gene therapy 11 (6), 479-484, 2011 | 146 | 2011 |
