关注
Chen Yu, PhD
Chen Yu, PhD
Principal Scientist at Novartis Institute for Biomedical Research (NIBR)
在 novartis.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Microglial function is distinct in different anatomical locations during retinal homeostasis and degeneration
EG O’Koren, C Yu, M Klingeborn, AYW Wong, CL Prigge, R Mathew, ...
Immunity 50 (3), 723-737. e7, 2019
2772019
Microglia versus monocytes: distinct roles in degenerative diseases of the retina
C Yu, C Roubeix, F Sennlaub, DR Saban
Trends in neurosciences 43 (6), 433-449, 2020
962020
Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
MT McClain, FJ Constantine, R Henao, Y Liu, EL Tsalik, TW Burke, ...
Nature communications 12 (1), 1079, 2021
792021
Neutrophils cause obstruction of eyelid sebaceous glands in inflammatory eye disease in mice
NJ Reyes, C Yu, R Mathew, CM Kunnen, J Kalnitsky, RL Redfern, ...
Science translational medicine 10 (451), eaas9164, 2018
522018
PRCD is essential for high-fidelity photoreceptor disc formation
WJ Spencer, JD Ding, TR Lewis, C Yu, S Phan, JN Pearring, KY Kim, ...
Proceedings of the National Academy of Sciences 116 (26), 13087-13096, 2019
462019
Mucosal-associated invariant T cell responses differ by sex in COVID-19
C Yu, S Littleton, NS Giroux, R Mathew, S Ding, J Kalnitsky, Y Yang, ...
Med 2 (6), 755-772. e5, 2021
302021
Annexin A5 regulates surface αvβ5 integrin for retinal clearance phagocytosis
C Yu, LE Muñoz, M Mallavarapu, M Herrmann, SC Finnemann
Journal of Cell Science 132 (20), jcs232439, 2019
272019
scDAPA: detection and visualization of dynamic alternative polyadenylation from single cell RNA-seq data
C Ye, Q Zhou, X Wu, C Yu, G Ji, DR Saban, QQ Li
Bioinformatics 36 (4), 1262-1264, 2020
262020
Expression and characterization of αvβ5 integrin on intestinal macrophages
AK Kumawat, C Yu, EA Mann, A Schridde, SC Finnemann, AMI Mowat
European journal of immunology 48 (7), 1181-1187, 2018
242018
Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model
DR Saban, RR Hodges, R Mathew, NJ Reyes, C Yu, R Kaye, W Swift, ...
Mucosal immunology 12 (1), 145-153, 2019
232019
Meibomian gland dysfunction is suppressed via selective inhibition of immune responses by topical LFA-1/ICAM antagonism with lifitegrast in the allergic eye disease (AED) model
PP Singh, C Yu, R Mathew, VL Perez, DR Saban
The ocular surface 21, 271-278, 2021
142021
Identification of a unique subretinal microglia type in retinal degeneration using single cell RNA-seq
C Yu, DR Saban
Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 181-186, 2019
72019
An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2
CK Harvest, TJ Abele, C Yu, CJ Beatty, ME Amason, ZP Billman, ...
Nature Communications 14 (1), 6686, 2023
62023
Retinal pre-conditioning by CD59a knockout protects against light-induced photoreceptor degeneration
D Song, B Wilson, L Zhao, R Bhuyan, M Bandyopadhyay, A Lyubarsky, ...
Plos one 11 (11), e0166348, 2016
42016
Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 Interactions
C Yu, EM Lad, R Mathew, S Littleton, Y Chen, K Schlepckow, S Degan, ...
bioRxiv, 2023
32023
Contribution of annexin A5 to diurnal phagocytosis by the retinal pigment epithelium
C Yu, LE Munoz, S Boeltz, SC Finnemann
Investigative Ophthalmology & Visual Science 57 (12), 237-237, 2016
32016
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2
C Yu, EM Lad, R Mathew, N Shiraki, S Littleton, Y Chen, J Hou, ...
Journal of Experimental Medicine 221 (3), e20231011, 2024
22024
Microglia Preserve Visual Function in a Mouse Model of Retinitis Pigmentosa with Rhodopsin-P23H Mutant
C Yu, DR Saban
Retinal Degenerative Diseases XIX: Mechanisms and Experimental Therapy, 421-425, 2023
12023
Advanced Flow Cytometry and Machine Learning for Profiling Ocular Leukocytes in Human Inflammatory Eye Disease
J Kalnitsky, R Mathew, C Yu, S Littleton, C Beatty, H Mousa, D Grewal, ...
Investigative Ophthalmology & Visual Science 64 (8), 3916-3916, 2023
12023
Single Cell RNA-Sequencing Points to an Inter-relationship between Corneal Macrophages and Dendritic Cells
S Littleton, C Yu, R Mathew, J Kalnitsky, DR Saban
Investigative Ophthalmology & Visual Science 62 (8), 923-923, 2021
12021
系统目前无法执行此操作,请稍后再试。
文章 1–20