| Specific killing of BRCA2-deficient tumours with inhibitors of poly (ADP-ribose) polymerase HE Bryant, N Schultz, HD Thomas, KM Parker, D Flower, E Lopez, S Kyle, ... Nature 434 (7035), 913-917, 2005 | 5677 | 2005 |
| Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans Journal of British Surgery 107 (11), 1440-1449, 2020 | 1529 | 2020 |
| PARP is activated at stalled forks to mediate Mre11‐dependent replication restart and recombination HE Bryant, E Petermann, N Schultz, AS Jemth, O Loseva, N Issaeva, ... The EMBO journal 28 (17), 2601-2615, 2009 | 725 | 2009 |
| Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ... Breast Cancer Research 15, 1-37, 2013 | 515 | 2013 |
| Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks N Saleh-Gohari, HE Bryant, N Schultz, KM Parker, TN Cassel, T Helleday Molecular and cellular biology, 2005 | 421 | 2005 |
| Distinct microRNA alterations characterize high-and low-grade bladder cancer JWF Catto, S Miah, HC Owen, H Bryant, K Myers, E Dudziec, S Larré, ... Cancer research 69 (21), 8472-8481, 2009 | 400 | 2009 |
| Transition metal complexes as photosensitisers in one-and two-photon photodynamic therapy LK McKenzie, HE Bryant, JA Weinstein Coordination Chemistry Reviews 379, 2-29, 2019 | 337 | 2019 |
| Reduced expression of miRNA-27a modulates cisplatin resistance in bladder cancer by targeting the cystine/glutamate exchanger SLC7A11 RM Drayton, E Dudziec, S Peter, S Bertz, A Hartmann, HE Bryant, ... Clinical cancer research 20 (7), 1990-2000, 2014 | 281 | 2014 |
| Poly (ADP-Ribose) polymerase is hyperactivated in homologous recombination–defective cells P Gottipati, B Vischioni, N Schultz, J Solomons, HE Bryant, T Djureinovic, ... Cancer research 70 (13), 5389-5398, 2010 | 271 | 2010 |
| PI3King the lock: targeting the PI3K/Akt/mTOR pathway as a novel therapeutic strategy in neuroblastoma D King, D Yeomanson, HE Bryant Journal of pediatric hematology/oncology 37 (4), 245-251, 2015 | 264 | 2015 |
| Poly (ADP-ribose) polymerase (PARP-1) in homologous recombination and as a target for cancer therapy T Helleday, HE Bryant, N Schultz Cell cycle 4 (9), 1176-1178, 2005 | 242 | 2005 |
| Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair HE Bryant, T Helleday Nucleic acids research 34 (6), 1685-1691, 2006 | 240 | 2006 |
| DNA repair in prostate cancer: biology and clinical implications J Mateo, G Boysen, CE Barbieri, HE Bryant, E Castro, PS Nelson, ... European urology 71 (3), 417-425, 2017 | 228 | 2017 |
| PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA O Loseva, AS Jemth, HE Bryant, H Schüler, L Lehtiö, T Karlberg, ... Journal of Biological Chemistry 285 (11), 8054-8060, 2010 | 203 | 2010 |
| Metal Complexes for Two‐Photon Photodynamic Therapy: A Cyclometallated Iridium Complex Induces Two‐Photon Photosensitization of Cancer Cells under Near‐IR Light LK McKenzie, IV Sazanovich, E Baggaley, M Bonneau, V Guerchais, ... Chemistry–A European Journal 23 (2), 234-238, 2017 | 167 | 2017 |
| Herpes simplex virus IE63 (ICP27) protein interacts with spliceosome-associated protein 145 and inhibits splicing prior to the first catalytic step HE Bryant, SE Wadd, AI Lamond, SJ Silverstein, JB Clements Journal of virology 75 (9), 4376-4385, 2001 | 149 | 2001 |
| The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links AZ Al-Minawi, YF Lee, D Håkansson, F Johansson, C Lundin, ... Nucleic acids research 37 (19), 6400-6413, 2009 | 121 | 2009 |
| The multifunctional herpes simplex virus IE63 protein interacts with heterogeneous ribonucleoprotein K and with casein kinase 2 S Wadd, H Bryant, O Filhol, JE Scott, TY Hsieh, RD Everett, JB Clements Journal of Biological Chemistry 274 (41), 28991-28998, 1999 | 110 | 1999 |
| Inhibition of poly (ADP-ribose) glycohydrolase (PARG) specifically kills BRCA2-deficient tumor cells C Fathers, RM Drayton, S Solovieva, HE Bryant Cell cycle 11 (5), 990-997, 2012 | 106 | 2012 |
| Signal transduction and transcription factor modification during reactivation of Epstein-Barr virus from latency H Bryant, PJ Farrell Journal of virology 76 (20), 10290-10298, 2002 | 95 | 2002 |
