| Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation H Higashi, A Nakaya, R Tsutsumi, K Yokoyama, Y Fujii, S Ishikawa, ... Journal of Biological Chemistry 279 (17), 17205-17216, 2004 | 368 | 2004 |
| Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA R Tsutsumi, A Takahashi, T Azuma, H Higashi, M Hatakeyama Molecular and cellular biology, 2006 | 279 | 2006 |
| Molecular anatomy and pathogenic actions of Helicobacter pylori CagA that underpin gastric carcinogenesis A Takahashi-Kanemitsu, CT Knight, M Hatakeyama Cellular & molecular immunology 17 (1), 50-63, 2020 | 206 | 2020 |
| SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver A Takahashi, R Tsutsumi, I Kikuchi, C Obuse, Y Saito, A Seidi, R Karisch, ... Molecular cell 43 (1), 45-56, 2011 | 141 | 2011 |
| Isolation of a distinct class of gain-of-function SHP-2 mutants with oncogenic RAS-like transforming activity from solid tumors D Miyamoto, M Miyamoto, A Takahashi, Y Yomogita, H Higashi, S Kondo, ... Oncogene 27 (25), 3508-3515, 2008 | 109 | 2008 |
| YAP and TAZ, Hippo signaling targets, act as a rheostat for nuclear SHP2 function R Tsutsumi, M Masoudi, A Takahashi, Y Fujii, T Hayashi, I Kikuchi, ... Developmental cell 26 (6), 658-665, 2013 | 105 | 2013 |
| Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis S Imai, T Ooki, N Murata-Kamiya, D Komura, K Tahmina, W Wu, ... Cell Host & Microbe 29 (6), 941-958. e10, 2021 | 102 | 2021 |
| High-molecular-weight hyaluronan is a hippo pathway ligand directing cell density-dependent growth inhibition via PAR1b T Ooki, N Murata-Kamiya, A Takahashi-Kanemitsu, W Wu, M Hatakeyama Developmental cell 49 (4), 590-604. e9, 2019 | 82 | 2019 |
| Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways I Kikuchi, A Takahashi-Kanemitsu, N Sakiyama, C Tang, PJ Tang, S Noda, ... Nature communications 7 (1), 12887, 2016 | 53 | 2016 |
| Transcriptional co-activator functions of YAP and TAZ are inversely regulated by tyrosine phosphorylation status of parafibromin C Tang, A Takahashi-Kanemitsu, I Kikuchi, C Ben, M Hatakeyama Iscience 1, 1-15, 2018 | 44 | 2018 |
| Determination of the catalytic activity of LEOPARD syndrome-associated SHP2 mutants toward parafibromin, a bona fide SHP2 substrate involved in Wnt signaling S Noda, A Takahashi, T Hayashi, S Tanuma, M Hatakeyama Biochemical and biophysical research communications 469 (4), 1133-1139, 2016 | 19 | 2016 |
| Transgenically expressed Helicobacter pylori CagA in vascular endothelial cells accelerates arteriosclerosis in mice K Tahmina, N Hikawa, A Takahashi-Kanemitsu, CT Knight, K Sato, F Itoh, ... Biochemical and Biophysical Research Communications 618, 79-85, 2022 | 10 | 2022 |
| The Helicobacter pylori CagA oncoprotein disrupts Wnt/PCP signaling and promotes hyperproliferation of pyloric gland base cells. A Takahashi-Kanemitsu, M Lu, CT Knight, T Yamamoto, T Hayashi, Y Mii, ... Science Signaling 16 (794), eabp9020, 2023 | 9 | 2023 |
| Alternative splicing reverses the cell-intrinsic and cell-extrinsic pro-oncogenic potentials of YAP1 C Ben, X Wu, A Takahashi-Kanemitsu, CT Knight, T Hayashi, ... Journal of Biological Chemistry 295 (41), 13965-13980, 2020 | 9 | 2020 |
| Blueprints from plane to space: outlook of next-generation three-dimensional histopathology EAS Akira Leon Yoshikawa, Takaki Omura, Atsushi Takahashi-Kanemitsu Cancer Science, 2024 | 2 | 2024 |
| Coevolution of the ileum with Brk/Ptk6 family kinases confers robustness to ileal homeostasis I Kikuchi, Y Iwashita, A Takahashi-Kanemitsu, M Koebisu, A Aiba, ... Biochemical and Biophysical Research Communications, 2023 | 1 | 2023 |
| Helicobacter pyloriがんタンパク質CagAが引き起こす胃がん発症のメカニズム A Takahashi-Kanemitsu, M Hatakeyama Japanese Journal of Helicobacter Research (日本ヘリコバクター学会誌) 26 (1), 12-17, 2024 | | 2024 |
| Alternative splicing confers non-cell-autonomous tumorigenic activities to YAP1 XI Wu, B Chi, A Takahashi-Kanemitsu, T Hayashi, M Hatakeyama CANCER SCIENCE 112, 264-264, 2021 | | 2021 |
| Establishment of mice conditionally expressing the Helicobacter pylori CagA oncoprotein CT Knight, A Takahashi, M Hatakeyama CANCER SCIENCE 109, 681-681, 2018 | | 2018 |
| Inverse Control of Transcription Co-Activator Function of YAP and TAZ by Tyrosine Phosphorylation Status of Parafibromin C Tang, A Takahashi-Kanemitsu, I Kikuchi, C Ben, M Hatakeyama CANCER SCIENCE 109, 1107-1107, 2018 | | 2018 |
Ippei KikuchiGraduate Student, Laboratory of Microbiology, Graduate School of Medicine, The University of Tokyo在 m.u-tokyo.ac.jp 的电子邮件经过验证
