Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors BR Tschida, NA Temiz, TP Kuka, LA Lee, JD Riordan, CA Tierrablanca, ... Cancer research 77 (23), 6576-6588, 2017 | 39 | 2017 |
The ancient sarcomeric myosins found in specialized muscles LA Lee, A Karabina, LJ Broadwell, LA Leinwand Skeletal muscle 9, 1-15, 2019 | 38 | 2019 |
Norrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function C Zhang, MB Lai, L Khandan, LA Lee, Z Chen, HJ Junge Nature communications 8 (1), 16050, 2017 | 29 | 2017 |
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains A Meller, JM Lotthammer, LG Smith, B Novak, LA Lee, CC Kuhn, ... Elife 12, e83602, 2023 | 19 | 2023 |
Expression of normally repressed myosin heavy chain 7b in the mammalian heart induces dilated cardiomyopathy AK Peter, AC Rossi, M Buvoli, CD Ozeroff, C Crocini, AR Perry, AE Buvoli, ... Journal of the American Heart Association 8 (15), e013318, 2019 | 18 | 2019 |
Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles LA Lee, SK Barrick, A Meller, J Walklate, JM Lotthammer, JW Tay, ... Journal of Biological Chemistry 299 (1), 2023 | 12 | 2023 |
Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS (V12) oncogene addiction in acute myeloid leukemia EJ Pomeroy, LA Lee, RDW Lee, DK Schirm, NA Temiz, J Ma, TA Gruber, ... Oncogene 36 (23), 3263-3273, 2017 | 12 | 2017 |
RALB provides critical survival signals downstream of Ras in acute myeloid leukemia CE Eckfeldt, EJ Pomeroy, RDW Lee, KS Hazen, LA Lee, BS Moriarity, ... Oncotarget 7 (40), 65147, 2016 | 7 | 2016 |
Nonproductive splicing prevents expression of MYH7b protein in the mammalian heart LA Lee, LJ Broadwell, M Buvoli, LA Leinwand Journal of the American Heart Association 10 (14), e020965, 2021 | 6 | 2021 |
Distinct effects of two hearing loss–associated mutations in the sarcomeric myosin MYH7b LA Lee, SK Barrick, AE Buvoli, J Walklate, WT Stump, M Geeves, ... Journal of Biological Chemistry 299 (5), 2023 | 1 | 2023 |
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains A Meller, JM Lotthammer, LG Smith, B Novak, LA Lee, CC Kuhn, ... bioRxiv, 2022.09. 05.506254, 2022 | 1 | 2022 |
CHRONIC TREATMENT WITH THE NOVEL SARCOMERE MODULATOR EDG-7500 IMPROVES LEFT VENTRICULAR DISTENSIBILITY AND CARDIAC OUTPUT RECRUITMENT UNDER STRESS IN A MINIPIG GENETIC MODEL OF … M Evanchik, C Emter, CL del Rio, E Dinatale, M Henze, S Roof, S St Clair, ... Journal of the American College of Cardiology 83 (13_Supplement), 365-365, 2024 | | 2024 |
Functional Divergence of the Atypical Sarcomeric Myosin Myh7b Supports Specialized Biological Roles across Species LA Lee University of Colorado at Boulder, 2022 | | 2022 |
Functional Differences in MYH7b That Contribute to Distinct Biological Roles across Species and in Health and Disease LA Lee, A Karabina, LA Leinwand Biophysical Journal 118 (3), 433a, 2020 | | 2020 |