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Eric Helfrich
Eric Helfrich
Professor of Natural Product Genomics, Goethe University Frankfurt, Germany
在 bio.uni-frankfurt.de 的电子邮件经过验证 - 首页
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Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
M Wang, JJ Carver, VV Phelan, LM Sanchez, N Garg, Y Peng, ...
Nature biotechnology 34 (8), 828-837, 2016
34472016
Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
8892015
An environmental bacterial taxon with a large and distinct metabolic repertoire
MC Wilson, T Mori, C Rückert, AR Uria, MJ Helf, K Takada, C Gernert, ...
Nature 506 (7486), 58-62, 2014
6332014
antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation
K Blin, S Shaw, HE Augustijn, ZL Reitz, F Biermann, M Alanjary, A Fetter, ...
Nucleic acids research 51 (W1), W46-W50, 2023
5532023
Biosynthesis of polyketides by trans-AT polyketide synthases
EJN Helfrich, J Piel
Natural product reports 33 (2), 231-316, 2016
3602016
A global metagenomic map of urban microbiomes and antimicrobial resistance
D Danko, D Bezdan, EE Afshin, S Ahsanuddin, C Bhattacharya, DJ Butler, ...
Cell 184 (13), 3376-3393. e17, 2021
2342021
MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters
BR Terlouw, K Blin, JC Navarro-Munoz, NE Avalon, MG Chevrette, ...
Nucleic acids research 51 (D1), D603-D610, 2023
1842023
Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome
EJN Helfrich, CM Vogel, R Ueoka, M Schäfer, F Ryffel, DB Müller, ...
Nature Microbiology 3 (8), 909-919, 2018
1682018
A microbiome-dependent gut–brain pathway regulates motivation for exercise
L Dohnalová, P Lundgren, JRE Carty, N Goldstein, SL Wenski, ...
Nature 612 (7941), 739-747, 2022
1432022
Metabolic footprint of epiphytic bacteria on Arabidopsis thaliana leaves
F Ryffel, EJN Helfrich, P Kiefer, L Peyriga, JC Portais, J Piel, JA Vorholt
The ISME journal 10 (3), 632-643, 2016
1392016
Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms
R Ueoka, AR Uria, S Reiter, T Mori, P Karbaum, EE Peters, EJN Helfrich, ...
Nature chemical biology 11 (9), 705-712, 2015
1372015
Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges
G Lackner, EE Peters, EJN Helfrich, J Piel
Proceedings of the National Academy of Sciences 114 (3), E347-E356, 2017
1362017
Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering
EJN Helfrich, GM Lin, CA Voigt, J Clardy
Beilstein journal of organic chemistry 15 (1), 2889-2906, 2019
1182019
Automated structure prediction of trans-acyltransferase polyketide synthase products
EJN Helfrich, R Ueoka, A Dolev, M Rust, RA Meoded, A Bhushan, ...
Nature chemical biology 15 (8), 813-821, 2019
1132019
Recent advances in genome-based polyketide discovery
EJN Helfrich, S Reiter, J Piel
Current opinion in biotechnology 29, 107-115, 2014
1132014
A community resource for paired genomic and metabolomic data mining
MA Schorn, S Verhoeven, L Ridder, F Huber, DD Acharya, AA Aksenov, ...
Nature Chemical Biology 17 (4), 363-368, 2021
1092021
A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli
M Rust, EJN Helfrich, MF Freeman, P Nanudorn, CM Field, C Rückert, ...
Proceedings of the National Academy of Sciences 117 (17), 9508-9518, 2020
902020
Single-bacterial genomics validates rich and varied specialized metabolism of uncultivated Entotheonella sponge symbionts
T Mori, JKB Cahn, MC Wilson, RA Meoded, V Wiebach, AFC Martinez, ...
Proceedings of the National Academy of Sciences 115 (8), 1718-1723, 2018
892018
Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A
SH Reisberg, Y Gao, AS Walker, EJN Helfrich, J Clardy, PS Baran
Science 367 (6476), 458-463, 2020
862020
Artificial intelligence for natural product drug discovery
MW Mullowney, KR Duncan, SS Elsayed, N Garg, JJJ van der Hooft, ...
Nature Reviews Drug Discovery 22 (11), 895-916, 2023
822023
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