Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking M Wang, JJ Carver, VV Phelan, LM Sanchez, N Garg, Y Peng, ... Nature biotechnology 34 (8), 828-837, 2016 | 3447 | 2016 |
Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 889 | 2015 |
An environmental bacterial taxon with a large and distinct metabolic repertoire MC Wilson, T Mori, C Rückert, AR Uria, MJ Helf, K Takada, C Gernert, ... Nature 506 (7486), 58-62, 2014 | 633 | 2014 |
antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation K Blin, S Shaw, HE Augustijn, ZL Reitz, F Biermann, M Alanjary, A Fetter, ... Nucleic acids research 51 (W1), W46-W50, 2023 | 553 | 2023 |
Biosynthesis of polyketides by trans-AT polyketide synthases EJN Helfrich, J Piel Natural product reports 33 (2), 231-316, 2016 | 360 | 2016 |
A global metagenomic map of urban microbiomes and antimicrobial resistance D Danko, D Bezdan, EE Afshin, S Ahsanuddin, C Bhattacharya, DJ Butler, ... Cell 184 (13), 3376-3393. e17, 2021 | 234 | 2021 |
MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters BR Terlouw, K Blin, JC Navarro-Munoz, NE Avalon, MG Chevrette, ... Nucleic acids research 51 (D1), D603-D610, 2023 | 184 | 2023 |
Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome EJN Helfrich, CM Vogel, R Ueoka, M Schäfer, F Ryffel, DB Müller, ... Nature Microbiology 3 (8), 909-919, 2018 | 168 | 2018 |
A microbiome-dependent gut–brain pathway regulates motivation for exercise L Dohnalová, P Lundgren, JRE Carty, N Goldstein, SL Wenski, ... Nature 612 (7941), 739-747, 2022 | 143 | 2022 |
Metabolic footprint of epiphytic bacteria on Arabidopsis thaliana leaves F Ryffel, EJN Helfrich, P Kiefer, L Peyriga, JC Portais, J Piel, JA Vorholt The ISME journal 10 (3), 632-643, 2016 | 139 | 2016 |
Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms R Ueoka, AR Uria, S Reiter, T Mori, P Karbaum, EE Peters, EJN Helfrich, ... Nature chemical biology 11 (9), 705-712, 2015 | 137 | 2015 |
Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges G Lackner, EE Peters, EJN Helfrich, J Piel Proceedings of the National Academy of Sciences 114 (3), E347-E356, 2017 | 136 | 2017 |
Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering EJN Helfrich, GM Lin, CA Voigt, J Clardy Beilstein journal of organic chemistry 15 (1), 2889-2906, 2019 | 118 | 2019 |
Automated structure prediction of trans-acyltransferase polyketide synthase products EJN Helfrich, R Ueoka, A Dolev, M Rust, RA Meoded, A Bhushan, ... Nature chemical biology 15 (8), 813-821, 2019 | 113 | 2019 |
Recent advances in genome-based polyketide discovery EJN Helfrich, S Reiter, J Piel Current opinion in biotechnology 29, 107-115, 2014 | 113 | 2014 |
A community resource for paired genomic and metabolomic data mining MA Schorn, S Verhoeven, L Ridder, F Huber, DD Acharya, AA Aksenov, ... Nature Chemical Biology 17 (4), 363-368, 2021 | 109 | 2021 |
A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli M Rust, EJN Helfrich, MF Freeman, P Nanudorn, CM Field, C Rückert, ... Proceedings of the National Academy of Sciences 117 (17), 9508-9518, 2020 | 90 | 2020 |
Single-bacterial genomics validates rich and varied specialized metabolism of uncultivated Entotheonella sponge symbionts T Mori, JKB Cahn, MC Wilson, RA Meoded, V Wiebach, AFC Martinez, ... Proceedings of the National Academy of Sciences 115 (8), 1718-1723, 2018 | 89 | 2018 |
Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A SH Reisberg, Y Gao, AS Walker, EJN Helfrich, J Clardy, PS Baran Science 367 (6476), 458-463, 2020 | 86 | 2020 |
Artificial intelligence for natural product drug discovery MW Mullowney, KR Duncan, SS Elsayed, N Garg, JJJ van der Hooft, ... Nature Reviews Drug Discovery 22 (11), 895-916, 2023 | 82 | 2023 |