Heterozygous germline mutations in the CBL tumor-suppressor gene cause a Noonan syndrome-like phenotype S Martinelli, A De Luca, E Stellacci, C Rossi, S Checquolo, F Lepri, ... The American Journal of Human Genetics 87 (2), 250-257, 2010 | 281 | 2010 |
Combined expression of pTα and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis D Bellavia, AF Campese, S Checquolo, A Balestri, A Biondi, G Cazzaniga, ... Proceedings of the National Academy of Sciences 99 (6), 3788-3793, 2002 | 267 | 2002 |
Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes E Anastasi, AF Campese, D Bellavia, A Bulotta, A Balestri, M Pascucci, ... The Journal of Immunology 171 (9), 4504-4511, 2003 | 187 | 2003 |
Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia V Kumar, R Palermo, C Talora, AF Campese, S Checquolo, D Bellavia, ... Leukemia 28 (12), 2324-2335, 2014 | 178 | 2014 |
Notch signaling activation as a hallmark for triple‐negative breast cancer subtype MV Giuli, E Giuliani, I Screpanti, D Bellavia, S Checquolo Journal of oncology 2019 (1), 8707053, 2019 | 145 | 2019 |
Notch3: from subtle structural differences to functional diversity D Bellavia, S Checquolo, AF Campese, MP Felli, A Gulino, I Screpanti Oncogene 27 (38), 5092-5098, 2008 | 118 | 2008 |
Wnt, Notch, and TGF-β pathways impinge on hedgehog signaling complexity: an open window on cancer M Pelullo, S Zema, F Nardozza, S Checquolo, I Screpanti, D Bellavia Frontiers in genetics 10, 711, 2019 | 116 | 2019 |
PKCθ mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia MP Felli, A Vacca, A Calce, D Bellavia, AF Campese, R Grillo, ... Oncogene 24 (6), 992-1000, 2005 | 92 | 2005 |
Pre‐TCR‐triggered ERK signalling‐dependent downregulation of E2A activity in Notch3‐induced T‐cell lymphoma C Talora, AF Campese, D Bellavia, M Pascucci, S Checquolo, ... EMBO reports 4 (11), 1067-1071, 2003 | 85 | 2003 |
Acetylation controls Notch3 stability and function in T-cell leukemia R Palermo, S Checquolo, A Giovenco, P Grazioli, V Kumar, AF Campese, ... Oncogene 31 (33), 3807-3817, 2012 | 67 | 2012 |
Notch3/Jagged1 circuitry reinforces notch signaling and sustains T-ALL M Pelullo, R Quaranta, C Talora, S Checquolo, S Cialfi, MP Felli, ... Neoplasia 16 (12), 1007-1017, 2014 | 61 | 2014 |
Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression G Franciosa, G Diluvio, F Del Gaudio, MV Giuli, R Palermo, P Grazioli, ... Oncogene 35 (36), 4741-4751, 2016 | 59 | 2016 |
Current trends in ATRA delivery for cancer therapy MV Giuli, PN Hanieh, E Giuliani, F Rinaldi, C Marianecci, I Screpanti, ... Pharmaceutics 12 (8), 707, 2020 | 54 | 2020 |
Notch signaling as a therapeutic target for acute lymphoblastic leukemia D Bellavia, R Palermo, MP Felli, I Screpanti, S Checquolo Expert Opinion on Therapeutic Targets 22 (4), 331-342, 2018 | 52 | 2018 |
NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest G Diluvio, F Del Gaudio, MV Giuli, G Franciosa, E Giuliani, R Palermo, ... Oncogenesis 7 (5), 42, 2018 | 46 | 2018 |
The molecular basis of notch signaling regulation: a complex simplicity R Palermo, S Checquolo, D Bellavia, C Talora, I Screpanti Current molecular medicine 14 (1), 34-44, 2014 | 46 | 2014 |
Opsonin-Deficient Nucleoproteic Corona Endows UnPEGylated Liposomes with Stealth Properties In Vivo F Giulimondi, E Vulpis, L Digiacomo, MV Giuli, A Mancusi, AL Capriotti, ... ACS nano 16 (2), 2088-2100, 2022 | 41 | 2022 |
Histone modifications drive aberrant Notch3 expression/activity and growth in T-ALL L Tottone, N Zhdanovskaya, Á Carmona Pestaña, M Zampieri, F Simeoni, ... Frontiers in oncology 9, 198, 2019 | 40 | 2019 |
Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway R Quaranta, M Pelullo, S Zema, F Nardozza, S Checquolo, DM Lauer, ... Cell Death & Disease 8 (7), e2942-e2942, 2017 | 40 | 2017 |
The deregulated expression of miR-125b in acute myeloid leukemia is dependent on the transcription factor C/EBPα P Vargas Romero, S Cialfi, R Palermo, C De Blasio, S Checquolo, ... Leukemia 29 (12), 2442-2445, 2015 | 40 | 2015 |