The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping B Heras, M Totsika, KM Peters, JJ Paxman, CL Gee, RJ Jarrott, ... Proceedings of the National Academy of Sciences 111 (1), 457-462, 2014 | 148 | 2014 |
A molecular chameleon for mapping subcellular polarity in an unfolded proteome environment TC Owyong, P Subedi, J Deng, E Hinde, JJ Paxman, JM White, W Chen, ... Angewandte Chemie 132 (25), 10215-10221, 2020 | 86 | 2020 |
The structure of the bacterial oxidoreductase enzyme DsbA in complex with a peptide reveals a basis for substrate specificity in the catalytic cycle of DsbA enzymes JJ Paxman, NA Borg, J Horne, PE Thompson, Y Chin, P Sharma, ... Journal of biological chemistry 284 (26), 17835-17845, 2009 | 83 | 2009 |
Targeting bacterial Dsb proteins for the development of anti-virulence agents RP Smith, JJ Paxman, MJ Scanlon, B Heras Molecules 21 (7), 811, 2016 | 68 | 2016 |
Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V SC Atkinson, MD Audsley, KG Lieu, GA Marsh, DR Thomas, SM Heaton, ... Scientific Reports 8 (1), 358, 2018 | 43 | 2018 |
Structural determinants defining the allosteric inhibition of an essential antibiotic target TPS da Costa, S Desbois, C Dogovski, MA Gorman, NE Ketaren, ... Structure 24 (8), 1282-1291, 2016 | 42 | 2016 |
Enzymology of bacterial lysine biosynthesis C Dogovski, SC Atkinson, SR Dommaraju, M Downton, L Hor, S Moore, ... Biochemistry, 2012 | 42 | 2012 |
Inhibition of diverse DsbA enzymes in multi-DsbA encoding pathogens M Totsika, D Vagenas, JJ Paxman, G Wang, R Dhouib, P Sharma, ... Antioxidants & redox signaling 29 (7), 653-666, 2018 | 41 | 2018 |
Autotransporter Adhesins in Escherichia coli Pathogenesis JL Vo, GC Martínez Ortiz, P Subedi, S Keerthikumar, S Mathivanan, ... Proteomics 17 (23-24), 1600431, 2017 | 37 | 2017 |
Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules JJ Paxman, AW Lo, MJ Sullivan, S Panjikar, M Kuiper, AE Whitten, ... Nature communications 10 (1), 1967, 2019 | 33 | 2019 |
Bioinformatics tools and resources for analyzing protein structures JJ Paxman, B Heras Proteome Bioinformatics, 209-220, 2017 | 28 | 2017 |
The Scs disulfide reductase system cooperates with the metallochaperone CueP in Salmonella copper resistance P Subedi, JJ Paxman, G Wang, AA Ukuwela, Z Xiao, B Heras Journal of Biological Chemistry 294 (44), 15876-15888, 2019 | 26 | 2019 |
Molecular and structural characterization of a novel Escherichia coli interleukin receptor mimic protein DG Moriel, B Heras, JJ Paxman, AW Lo, L Tan, MJ Sullivan, SJ Dando, ... MBio 7 (2), 10.1128/mbio. 02046-15, 2016 | 26 | 2016 |
Molecular and structural insights into an asymmetric proteolytic complex (ClpP1P2) from Mycobacterium smegmatis J Nagpal, JJ Paxman, JE Zammit, AA Thomas, KN Truscott, B Heras, ... Scientific reports 9 (1), 18019, 2019 | 21 | 2019 |
Differential homotypic and heterotypic interactions of antigen 43 (Ag43) variants in autotransporter-mediated bacterial autoaggregation V Ageorges, M Schiavone, G Jubelin, N Caccia, P Ruiz, I Chafsey, ... Scientific reports 9 (1), 11100, 2019 | 19 | 2019 |
Phylogenetic classification and functional review of autotransporters KR Clarke, L Hor, A Pilapitiya, J Luirink, JJ Paxman, B Heras Frontiers in Immunology 13, 921272, 2022 | 18 | 2022 |
Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens RP Smith, B Mohanty, S Mowlaboccus, JJ Paxman, ML Williams, ... Journal of Biological Chemistry 293 (43), 16559-16571, 2018 | 12 | 2018 |
Sortase-assembled pili promote extracellular electron transfer and iron acquisition in Enterococcus faecalis biofilm LN Lam, JJ Wong, A Matysik, JJ Paxman, KKL Chong, PM Low, ZS Chua, ... Biorxiv, 601666, 2019 | 11 | 2019 |
Variation of Antigen 43 self-association modulates bacterial compacting within aggregates and biofilms JL Vo, GCM Ortiz, M Totsika, AW Lo, SJ Hancock, AE Whitten, L Hor, ... npj Biofilms and Microbiomes 8 (1), 20, 2022 | 9 | 2022 |
Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities P Subedi, JJ Paxman, G Wang, L Hor, Y Hong, AD Verderosa, AE Whitten, ... Antioxidants & Redox Signaling 35 (1), 21-39, 2021 | 8 | 2021 |