关注
Prabuddha Waduge, Ph.D.
Prabuddha Waduge, Ph.D.
Postdoctoral Associate, Baylor College of Medicine
在 bcm.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Design, multigram synthesis, and in vitro and in vivo evaluation of propylamycin: a semisynthetic 4, 5-deoxystreptamine class aminoglycoside for the treatment of drug-resistant …
T Matsushita, GC Sati, N Kondasinghe, MG Pirrone, T Kato, P Waduge, ...
Journal of the American Chemical Society 141 (12), 5051-5061, 2019
562019
An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram‐negative Pathogens and Reduced ex vivo Cochleotoxicity
A Sonousi, JCK Quirke, P Waduge, T Janusic, M Gysin, K Haldimann, ...
ChemMedChem 16 (2), 335-339, 2021
202021
Chemical probing for examining the structure of modified RNAs and ligand binding to RNA
P Waduge, Y Sakakibara, CS Chow
Methods 156, 110-120, 2019
182019
Secretogranin III stringently regulates pathological but not physiological angiogenesis in oxygen-induced retinopathy
C Dai, P Waduge, L Ji, C Huang, Y He, H Tian, E Zuniga-Sanchez, ...
Cellular and Molecular Life Sciences 79 (1), 63, 2022
122022
Selectively targeting disease-restricted secretogranin III to alleviate choroidal neovascularization
L Ji, P Waduge, L Hao, A Kaur, W Wan, Y Wu, H Tian, J Zhang, ...
FASEB journal: official publication of the Federation of American Societies …, 2022
102022
Comparative ligandomics implicates secretogranin III as a disease‐restricted angiogenic factor in laser‐induced choroidal neovascularization
L Ji, P Waduge, W Wan, H Tian, J Li, J Zhang, R Chen, W Li
The FEBS journal 289 (12), 3521-3534, 2022
82022
Use of a fluorescence assay to determine relative affinities of semisynthetic aminoglycosides to small RNAs representing bacterial and mitochondrial A sites
P Waduge, GC Sati, D Crich, CS Chow
Bioorganic & medicinal chemistry 27 (22), 115121, 2019
62019
Secretogranin III selectively promotes vascular leakage in the deep vascular plexus of diabetic retinopathy
L Ji, P Waduge, Y Wu, C Huang, A Kaur, P Oliveira, H Tian, J Zhang, ...
International Journal of Molecular Sciences 24 (13), 10531, 2023
42023
Profiling disease-selective drug targets: From proteomics to ligandomics
P Waduge, H Tian, KA Webster, W Li
Drug discovery today 28 (3), 103430, 2023
42023
Anti-Scg3 Gene Therapy to Treat Choroidal Neovascularization in Mice
C Huang, L Ji, A Kaur, H Tian, P Waduge, KA Webster, W Li
Biomedicines 11 (7), 1910, 2023
32023
A method for rapid and reliable quantification of VEGF-cell binding activity
P Waduge, A Kaur, W Li
Biochemical and Biophysical Research Communications 727, 150321, 2024
2024
Optimal Humanized Scg3-Neutralizing Antibodies for Anti-Angiogenic Therapy of Diabetic Retinopathy
C Huang, P Waduge, A Kaur, H Tian, CY Weng, JT Stout, IH Pang, ...
International Journal of Molecular Sciences 25 (17), 9507, 2024
2024
A rapid and convenient method to quantify VEGF binding to cells
P Waduge, A Kaur, W Li
Investigative Ophthalmology & Visual Science 65 (7), 1928-1928, 2024
2024
Ex vivo ligandomics to profile diabetic vs. healthy retinal cells for drug target discovery
W Li, P Waduge, C Huang, Y Li, J Li
Investigative Ophthalmology & Visual Science 65 (7), 317-317, 2024
2024
Anti-Scg3 therapy of oxygen-induced retinopathy in a canine model
B Zhang, C Huang, GJ Louise, D Jackson, P Waduge, RA Veettil, X Lin, ...
Investigative Ophthalmology & Visual Science 65 (7), 296-296, 2024
2024
Generation of optimal humanized Scg3-neutralizing antibodies for anti-angiogenic therapy
C Huang, A Kaur, P Waduge, CY Weng, H Tian, W Li
Investigative Ophthalmology & Visual Science 65 (7), 6115-6115, 2024
2024
Exploiting retinal endothelial heterogeneity for disease-targeted therapy of diabetic retinopathy
P Waduge, L Ji, Y Wu, C Huang, A Kaur, P Oliveira, H Tian, J Zhang, ...
Investigative Ophthalmology & Visual Science 64 (8), 997-997, 2023
2023
Ligandomics: A new technology to globally map disease-selective angiogenic factors for ocular therapeutics
W Li, P Waduge, H Tian, KA Webster
Investigative Ophthalmology & Visual Science 64 (8), 1868-1868, 2023
2023
Exploring the Binding of Aminoglycosides and Effect of Peptides on Functionally Important Regions of the Ribosome
PMD Waduge
Wayne State University, 2019
2019
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