Transition-metal-free catalytic synthesis of 1, 5-diaryl-1, 2, 3-triazoles SW Kwok, JR Fotsing, RJ Fraser, VO Rodionov, VV Fokin Organic letters 12 (19), 4217-4219, 2010 | 332 | 2010 |
Modulation of chemosensory receptors and ligands associated therewith C Tachdjian, DS Karanewsky, XQ Tang, X Li, F Zhang, G Servant, Q Chen, ... US Patent 9,181,276, 2015 | 184 | 2015 |
NH-1, 2, 3-triazole inhibitors of the VIM-2 metallo-β-lactamase T Weide, SA Saldanha, D Minond, TP Spicer, JR Fotsing, M Spaargaren, ... ACS medicinal chemistry letters 1 (4), 150-154, 2010 | 108 | 2010 |
Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template NP Grimster, B Stump, JR Fotsing, T Weide, TT Talley, JG Yamauchi, ... Journal of the American Chemical Society 134 (15), 6732-6740, 2012 | 95 | 2012 |
Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries D Minond, SA Saldanha, P Subramaniam, M Spaargaren, T Spicer, ... Bioorganic & medicinal chemistry 17 (14), 5027-5037, 2009 | 63 | 2009 |
Compounds that inhibit (block) bitter taste in composition and use thereof DS Karanewsky, JR Fotsing, C Tachdjian, M Arellano US Patent 8,076,491, 2011 | 42 | 2011 |
Compounds useful as modulators of TRPM8 AP Patron, A Noncovich, J Ung, T Davis, JR Fotsing, C Priest, C Tachdjian US Patent 9,732,071, 2017 | 34 | 2017 |
First propargyl azides bearing strong acceptor substituents and their effective conversion into allenyl azides: influence of the electronic effects of substituents on the … JR Fotsing, K Banert European journal of organic chemistry 2005 (17), 3704-3714, 2005 | 32 | 2005 |
Reactions of unsaturated azides; Part 17: An efficient strategy for the synthesis of small-ring heterocycles via isomerization of 2-Halo-2H-azirines JR Fotsing, K Banert Synthesis 2006 (02), 261-272, 2006 | 27 | 2006 |
Photolysis of open-chain 1, 2-diazidoalkenes: generation of 2-azido-2H-azirines, formyl cyanide, and formyl isocyanide K Banert, JR Fotsing, M Hagedorn, HP Reisenauer, G Maier Tetrahedron 64 (24), 5645-5648, 2008 | 24 | 2008 |
Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates JG Yamauchi, K Gomez, N Grimster, M Dufouil, A Nemecz, JR Fotsing, ... Molecular Pharmacology 82 (4), 687-699, 2012 | 21 | 2012 |
First successful synthesis, isolation and characterization of open-chain 1, 2-diazidoethenes JR Fotsing, M Hagedorn, K Banert Tetrahedron 61 (37), 8904-8909, 2005 | 21 | 2005 |
Discovery and development of S6821 and S7958 as potent TAS2R8 antagonists JR Fotsing, V Darmohusodo, AP Patron, BW Ching, T Brady, M Arellano, ... Journal of Medicinal Chemistry 63 (9), 4957-4977, 2020 | 14 | 2020 |
Sweet flavor modifier S Adamski-Werner, V Darmohusodo, C Tachdjian, D Karanewsky, ... US Patent 9,475,803, 2016 | 13 | 2016 |
New Way to Methylene‐2H‐azirines and Their Use as Powerful Intermediates for the Stereo‐ and Regioselective Synthesis of Compounds with Vinylamine … JR Fotsing, K Banert European journal of organic chemistry 2006 (16), 3617-3625, 2006 | 10 | 2006 |
Sweet flavor modifier S Adamski-Werner, V Darmohusodo, C Tachdjian, D Karanewsky, ... US Patent 9,695,162, 2017 | 7 | 2017 |
Compounds that inhibit (block) bitter taste in composition and use thereof DS Karanewsky, JR Fotsing, C Tachdjian, M Arellano US Patent 8,445,692, 2013 | 7 | 2013 |
Compounds useful as modulators of TRPM8 AP Patron, A Noncovich, T Davis, C Priest, JR Fotsing, J Ung, C Tachdjian US Patent 10,392,371, 2019 | 5 | 2019 |
Toxicological evaluation of the flavour ingredient N-(1-((4-amino-2, 2-dioxido-1H-benzo [c][1, 2, 6] thiadiazin-5-yl) oxy)-2-methylpropan-2-yl)-2, 6-dimethylisonicotinamide (S2218) DS Karanewsky, G Servant, H Liu, B Chi, L Ida, M Saganich, S Werner, ... Toxicology Reports 4, 507-520, 2017 | 3 | 2017 |
Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that … DS Karanewsky, JR Fotsing, C Tachdjian, M Arellano US Patent 9,247,759, 2016 | 3 | 2016 |