Extreme drug tolerance of Mycobacterium tuberculosis in caseum JP Sarathy, LE Via, D Weiner, L Blanc, H Boshoff, EA Eugenin, ... Antimicrobial agents and chemotherapy 62 (2), 10.1128/aac. 02266-17, 2018 | 187 | 2018 |
Fatty acid synthesis is required for breast cancer brain metastasis GB Ferraro, A Ali, A Luengo, DP Kodack, A Deik, KL Abbott, D Bezwada, ... Nature cancer 2 (4), 414-428, 2021 | 179 | 2021 |
Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids L Blanc, M Gilleron, J Prandi, O Song, MS Jang, B Gicquel, D Drocourt, ... Proceedings of the National Academy of Sciences 114 (42), 11205-11210, 2017 | 105 | 2017 |
Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance H Safi, P Gopal, S Lingaraju, S Ma, C Levine, V Dartois, M Yee, L Li, ... Proceedings of the National Academy of Sciences 116 (39), 19665-19674, 2019 | 102 | 2019 |
Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific V Guerrini, B Prideaux, L Blanc, N Bruiners, R Arrigucci, S Singh, ... PLoS pathogens 14 (8), e1007223, 2018 | 94 | 2018 |
Unraveling drug penetration of echinocandin antifungals at the site of infection in an intra-abdominal abscess model Y Zhao, B Prideaux, Y Nagasaki, MH Lee, PY Chen, L Blanc, H Ho, ... Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 01009-17, 2017 | 86 | 2017 |
Ethambutol partitioning in tuberculous pulmonary lesions explains its clinical efficacy M Zimmerman, J Lestner, B Prideaux, P O'Brien, I Dias-Freedman, ... Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00924-17, 2017 | 79 | 2017 |
Visualization of mycobacterial biomarkers and tuberculosis drugs in infected tissue by MALDI-MS imaging L Blanc, A Lenaerts, V Dartois, B Prideaux Analytical Chemistry 90 (10), 6275-6282, 2018 | 73 | 2018 |
Multimodal imaging based on vibrational spectroscopies and mass spectrometry imaging applied to biological tissue: a multiscale and multiomics review M Tuck, L Blanc, R Touti, NH Patterson, S Van Nuffel, S Villette, ... Analytical chemistry 93 (1), 445-477, 2020 | 59 | 2020 |
Fluoroquinolone efficacy against tuberculosis is driven by penetration into lesions and activity against resident bacterial populations J Sarathy, L Blanc, N Alvarez-Cabrera, P O’brien, I Dias-Freedman, ... Antimicrobial agents and chemotherapy 63 (5), 10.1128/aac. 02516-18, 2019 | 55 | 2019 |
High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types L Blanc, IB Daudelin, BK Podell, PY Chen, M Zimmerman, AJ Martinot, ... Elife 7, e41115, 2018 | 54 | 2018 |
An explant technique for high-resolution imaging and manipulation of mycobacterial granulomas MR Cronan, MA Matty, AF Rosenberg, L Blanc, CJ Pyle, ST Espenschied, ... Nature methods 15 (12), 1098-1107, 2018 | 42 | 2018 |
MALDI-MSI towards multimodal imaging: challenges and perspectives M Tuck, F Grélard, L Blanc, N Desbenoit Frontiers in Chemistry 10, 904688, 2022 | 37 | 2022 |
Spatial quantification of drugs in pulmonary tuberculosis lesions by laser capture microdissection liquid chromatography mass spectrometry (LCM-LC/MS) M Zimmerman, L Blanc, PY Chen, V Dartois, B Prideaux JoVE (Journal of Visualized Experiments), e57402, 2018 | 37 | 2018 |
Crucial role of fatty acid oxidation in asthmatic bronchial smooth muscle remodelling P Esteves, L Blanc, A Celle, I Dupin, E Maurat, N Amoedo, G Cardouat, ... European Respiratory Journal 58 (5), 2021 | 36 | 2021 |
Impact of immunopathology on the antituberculous activity of pyrazinamide L Blanc, JP Sarathy, N Alvarez Cabrera, P O’brien, I Dias-Freedman, ... Journal of Experimental Medicine 215 (8), 1975-1986, 2018 | 33 | 2018 |
Gram-positive bacterial lipoglycans based on a glycosylated diacylglycerol lipid anchor are microbe-associated molecular patterns recognized by TLR2 L Blanc, R Castanier, AK Mishra, A Ray, GS Besra, I Sutcliffe, ... PLoS One 8 (11), e81593, 2013 | 23 | 2013 |
Mass spectrometry imaging of mice brain lipid profile changes over time under high fat diet G Sighinolfi, S Clark, L Blanc, D Cota, B Rhourri-Frih Scientific Reports 11 (1), 19664, 2021 | 20 | 2021 |
A TLR2-Activating Fraction From Mycobacterium abscessus Rough Variant Demonstrates Vaccine and Diagnostic Potential V Le Moigne, AL Roux, A Jobart-Malfait, L Blanc, K Chaoui, ... Frontiers in Cellular and Infection Microbiology 10, 432, 2020 | 13 | 2020 |
A novel tool to identify bactericidal compounds against vulnerable targets in drug-tolerant M. tuberculosis found in caseum JP Sarathy, M Xie, RM Jones, A Chang, P Osiecki, D Weiner, WS Tsao, ... MBio 14 (2), e00598-23, 2023 | 6 | 2023 |