Epicatechin, catechin, and dimeric procyanidins inhibit PMA‐induced NF‐κB activation at multiple steps in Jurkat T cells GG Mackenzie, F Carrasquedo, JM Delfino, CL Keen, CG Fraga, PI Oteiza The FASEB journal 18 (1), 167-169, 2004 | 252 | 2004 |
Curcumin induces cell‐arrest and apoptosis in association with the inhibition of constitutively active NF‐κB and STAT3 pathways in Hodgkin's lymphoma cells GG Mackenzie, N Queisser, ML Wolfson, CG Fraga, AM Adamo, PI Oteiza International journal of cancer 123 (1), 56-65, 2008 | 182 | 2008 |
Zinc, oxidant-triggered cell signaling, and human health PI Oteiza, GG Mackenzie Molecular aspects of medicine 26 (4-5), 245-255, 2005 | 168 | 2005 |
Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models R Wei, L Mao, P Xu, X Zheng, RM Hackman, GG Mackenzie, Y Wang Food & function 9 (11), 5682-5696, 2018 | 140 | 2018 |
The role of zinc in the modulation of neuronal proliferation and apoptosis AM Adamo, MP Zago, GG Mackenzie, L Aimo, CL Keen, A Keenan, ... Neurotoxicity research 17, 1-14, 2010 | 137 | 2010 |
Metals in neurodegeneration: involvement of oxidants and oxidant-sensitive transcription factors PI Oteiza, GG Mackenzie, SV Verstraeten Molecular aspects of medicine 25 (1-2), 103-115, 2004 | 107 | 2004 |
Low intracellular zinc impairs the translocation of activated NF-κB to the nuclei in human neuroblastoma IMR-32 cells GG Mackenzie, MP Zago, CL Keen, PI Oteiza Journal of Biological Chemistry 277 (37), 34610-34617, 2002 | 103 | 2002 |
Dimeric procyanidins are inhibitors of NF-κB–DNA binding GG Mackenzie, JM Delfino, CL Keen, CG Fraga, PI Oteiza Biochemical pharmacology 78 (9), 1252-1262, 2009 | 93 | 2009 |
Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice GG Mackenzie, L Huang, N Alston, N Ouyang, K Vrankova, ... PloS one 8 (5), e61532, 2013 | 88 | 2013 |
Microtubules are required for NF‐κB nuclear translocation in neuroblastoma IMR‐32 cells: modulation by zinc GG Mackenzie, CL Keen, PI Oteiza Journal of neurochemistry 99 (2), 402-415, 2006 | 80 | 2006 |
Differential Modulation of MAP Kinases by Zinc Deficiency in IMR-32 Cells: Role of H2O2 MP Zago, GG Mackenzie, AM Adamo, CL Keen, PI Oteiza Antioxidants & Redox Signaling 7 (11-12), 1773-1782, 2005 | 73 | 2005 |
Dimeric procyanidin B2 inhibits constitutively active NF-κB in Hodgkin's lymphoma cells independently of the presence of IκB mutations GG Mackenzie, AM Adamo, NP Decker, PI Oteiza biochemical pharmacology 75 (7), 1461-1471, 2008 | 72 | 2008 |
Pancreatic cancer: A critical review of dietary risk AA Salem, GG Mackenzie Nutrition research 52, 1-13, 2018 | 68 | 2018 |
Curcumin formulated in solid lipid nanoparticles has enhanced efficacy in Hodgkin's lymphoma in mice J Guorgui, R Wang, G Mattheolabakis, GG Mackenzie Archives of biochemistry and biophysics 648, 12-19, 2018 | 67 | 2018 |
Phospho-sulindac (OXT-328), a novel sulindac derivative, is safe and effective in colon cancer prevention in mice GG Mackenzie, Y Sun, L Huang, G Xie, N Ouyang, RC Gupta, F Johnson, ... Gastroenterology 139 (4), 1320-1332, 2010 | 66 | 2010 |
Epigallocatechin-3-gallate (EGCG) suppresses pancreatic cancer cell growth, invasion, and migration partly through the inhibition of Akt pathway and epithelial–mesenchymal … R Wei, NE Cortez Penso, RM Hackman, Y Wang, GG Mackenzie Nutrients 11 (8), 1856, 2019 | 65 | 2019 |
The novel phospho‐non‐steroidal anti‐inflammatory drugs, OXT‐328, MDC‐22 and MDC‐917, inhibit adjuvant‐induced arthritis in rats L Huang, GG Mackenzie, N Ouyang, Y Sun, G Xie, F Johnson, ... British journal of pharmacology 162 (7), 1521-1533, 2011 | 65 | 2011 |
Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APCMin/+ Mice JS Son, S Khair, DW Pettet III, N Ouyang, X Tian, Y Zhang, W Zhu, ... PloS one 10 (6), e0127985, 2015 | 61 | 2015 |
A deficit in zinc availability can cause alterations in tubulin thiol redox status in cultured neurons and in the developing fetal rat brain GG Mackenzie, GA Salvador, C Romero, CL Keen, PI Oteiza Free Radical Biology and Medicine 51 (2), 480-489, 2011 | 61 | 2011 |
Modulation of transcription factor NF-κB in Hodgkin's lymphoma cell lines: Effect of (−)-epicatechin GG Mackenzie, PI Oteiza Free Radical Research 40 (10), 1086-1094, 2006 | 60 | 2006 |