| Microfluidics integrated biosensors: A leading technology towards lab-on-a-chip and sensing applications G Luka, A Ahmadi, H Najjaran, E Alocilja, M DeRosa, K Wolthers, A Malki, ... Sensors 15 (12), 30011-30031, 2015 | 548 | 2015 |
| Identification and in vitro biological activities of hop proanthocyanidins: inhibition of nNOS activity and scavenging of reactive nitrogen species JF Stevens, CL Miranda, KR Wolthers, M Schimerlik, ML Deinzer, ... Journal of Agricultural and Food Chemistry 50 (12), 3435-3443, 2002 | 143 | 2002 |
| Mitochondrial transcription factor A (Tfam) is a pro-inflammatory extracellular signaling molecule recognized by brain microglia JP Little, S Simtchouk, SM Schindler, EB Villanueva, NE Gill, DG Walker, ... Molecular and Cellular Neuroscience 60, 88-96, 2014 | 77 | 2014 |
| Molecular dissection of human methionine synthase reductase: determination of the flavin redox potentials in full-length enzyme and isolated flavin-binding domains KR Wolthers, J Basran, AW Munro, NS Scrutton Biochemistry 42 (13), 3911-3920, 2003 | 66 | 2003 |
| Kinetic and thermodynamic characterization of the common polymorphic variants of human methionine synthase reductase H Olteanu, KR Wolthers, AW Munro, NS Scrutton, R Banerjee Biochemistry 43 (7), 1988-1997, 2004 | 61 | 2004 |
| Protein interactions in the human methionine synthase− methionine synthase reductase complex and implications for the mechanism of enzyme reactivation KR Wolthers, NS Scrutton Biochemistry 46 (23), 6696-6709, 2007 | 59 | 2007 |
| Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4, 5-aminomutase KR Wolthers, C Levy, NS Scrutton, D Leys Journal of Biological Chemistry 285 (18), 13942-13950, 2010 | 58 | 2010 |
| Mechanism of coenzyme binding to human methionine synthase reductase revealed through the crystal structure of the FNR-like module and isothermal titration calorimetry KR Wolthers, X Lou, HS Toogood, D Leys, NS Scrutton Biochemistry 46 (42), 11833-11844, 2007 | 51 | 2007 |
| Cobalamin uptake and reactivation occurs through specific protein interactions in the methionine synthase–methionine synthase reductase complex KR Wolthers, NS Scrutton The FEBS Journal 276 (7), 1942-1951, 2009 | 42 | 2009 |
| Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4, 5-aminomutase KR Wolthers, SEJ Rigby, NS Scrutton Journal of Biological Chemistry 283 (50), 34615-34625, 2008 | 42 | 2008 |
| Electron transfer in human methionine synthase reductase studied by stopped-flow spectrophotometry KR Wolthers, NS Scrutton Biochemistry 43 (2), 490-500, 2004 | 39 | 2004 |
| Crystal structure and solution characterization of the activation domain of human methionine synthase KR Wolthers, HS Toogood, TA Jowitt, KR Marshall, D Leys, NS Scrutton The FEBS Journal 274 (3), 738-750, 2007 | 24 | 2007 |
| Mutagenesis of a conserved glutamate reveals the contribution of electrostatic energy to adenosylcobalamin Co–C bond homolysis in ornithine 4, 5-aminomutase and methylmalonyl … C Makins, AV Pickering, C Mariani, KR Wolthers Biochemistry 52 (5), 878-888, 2013 | 21 | 2013 |
| Kinetic analysis of cytochrome P450 reductase from Artemisia annua reveals accelerated rates of NADPH‐dependent flavin reduction S Simtchouk, JL Eng, CE Meints, C Makins, KR Wolthers The FEBS journal 280 (24), 6627-6642, 2013 | 20 | 2013 |
| Reaction of Neuronal Nitric-Oxide Synthase with 2, 6-Dichloroindolphenol and Cytochrome c 3+: Influence of the Electron Acceptor and Binding of Ca2+-Activated Calmodulin on the … KR Wolthers, MI Schimerlik Biochemistry 40 (15), 4722-4737, 2001 | 20 | 2001 |
| Kinetic characterization of acetone monooxygenase from Gordonia sp. strain TY-5 OB Fordwour, G Luka, M Hoorfar, KR Wolthers AMB Express 8, 1-13, 2018 | 18 | 2018 |
| Tryptophan 697 modulates hydride and interflavin electron transfer in human methionine synthase reductase CE Meints, FS Gustafsson, NS Scrutton, KR Wolthers Biochemistry 50 (51), 11131-11142, 2011 | 18 | 2011 |
| Structural and kinetic insight into the biosynthesis of H2S and l-lanthionine from l-cysteine by a pyridoxal l-phosphate-dependent enzyme from Fusobacterium nucleatum RG Mothersole, KR Wolthers Biochemistry 58 (34), 3592-3603, 2019 | 17 | 2019 |
| Kinetic analysis of electron flux in cytochrome P450 reductases reveals differences in rate-determining steps in plant and mammalian enzymes DA Whitelaw, R Tonkin, CE Meints, KR Wolthers Archives of biochemistry and biophysics 584, 107-115, 2015 | 16 | 2015 |
| ELDOR spectroscopy reveals that energy landscapes in human methionine synthase reductase are extensively remodelled following ligand and partner protein binding SEJ Rigby, X Lou, HS Toogood, KR Wolthers, NS Scrutton ChemBioChem 12 (6), 863-867, 2011 | 15 | 2011 |
