A photoinducible 1, 3‐dipolar cycloaddition reaction for rapid, selective modification of tetrazole‐containing proteins W Song, Y Wang, J Qu, MM Madden, Q Lin Angewandte Chemie International Edition 47 (15), 2832-2835, 2008 | 478 | 2008 |
Bioorthogonal chemistry: strategies and recent developments CP Ramil, Q Lin Chemical communications 49 (94), 11007-11022, 2013 | 426 | 2013 |
Selective functionalization of a genetically encoded alkene-containing protein via “photoclick chemistry” in bacterial cells W Song, Y Wang, J Qu, Q Lin Journal of the American Chemical Society 130 (30), 9654-9655, 2008 | 425 | 2008 |
Bioorthogonal chemistry: recent progress and future directions RKV Lim, Q Lin Chemical Communications 46 (10), 1589-1600, 2010 | 335 | 2010 |
Protein surface recognition by synthetic receptors: A route to novel submicromolar inhibitors for α-chymotrypsin HS Park, Q Lin, AD Hamilton Journal of the American Chemical Society 121 (1), 8-13, 1999 | 299 | 1999 |
Copper-free Sonogashira cross-coupling for functionalization of alkyne-encoded proteins in aqueous medium and in bacterial cells N Li, RKV Lim, S Edwardraja, Q Lin Journal of the American Chemical Society 133 (39), 15316-15319, 2011 | 297 | 2011 |
Bioorthogonal chemistry SL Scinto, DA Bilodeau, R Hincapie, W Lee, SS Nguyen, M Xu, ... Nature Reviews Methods Primers 1 (1), 30, 2021 | 271 | 2021 |
Genetically encoded cyclopropene directs rapid, photoclick‐chemistry‐mediated protein labeling in mammalian cells Z Yu, Y Pan, Z Wang, J Wang, Q Lin Angewandte Chemie 124 (42), 10752-10756, 2012 | 248 | 2012 |
Fast alkene functionalization in vivo by photoclick chemistry: HOMO lifting of nitrile imine dipoles Y Wang, W Song, WJ Hu, Q Lin Angewandte Chemie International Edition 48 (29), 5330-5333, 2009 | 245 | 2009 |
Photoinducible bioorthogonal chemistry: a spatiotemporally controllable tool to visualize and perturb proteins in live cells RKV Lim, Q Lin Accounts of Chemical Research 44 (9), 828-839, 2011 | 244 | 2011 |
Convenient synthesis of highly functionalized pyrazolines via mild, photoactivated 1, 3-dipolar cycloaddition Y Wang, CI Rivera Vera, Q Lin Organic letters 9 (21), 4155-4158, 2007 | 222 | 2007 |
Light-triggered click chemistry GS Kumar, Q Lin Chemical reviews 121 (12), 6991-7031, 2020 | 201 | 2020 |
Rational design of proteolytically stable, cell-permeable peptide-based selective Mcl-1 inhibitors A Muppidi, K Doi, S Edwardraja, EJ Drake, AM Gulick, HG Wang, Q Lin Journal of the American Chemical Society 134 (36), 14734-14737, 2012 | 184 | 2012 |
Fluorogenic, two-photon-triggered photoclick chemistry in live mammalian cells Z Yu, TY Ohulchanskyy, P An, PN Prasad, Q Lin Journal of the American Chemical Society 135 (45), 16766-16769, 2013 | 183 | 2013 |
Discovery of long-wavelength photoactivatable diaryltetrazoles for bioorthogonal 1, 3-dipolar cycloaddition reactions. Y Wang, WJ Hu, W Song, RK Lim, Q Lin Organic letters 10 (17), 3725-3728, 2008 | 175 | 2008 |
Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice MA Blaskovich, Q Lin, FL Delarue, J Sun, HS Park, D Coppola, ... Nature biotechnology 18 (10), 1065-1070, 2000 | 173 | 2000 |
A biosynthetic route to photoclick chemistry on proteins J Wang, W Zhang, W Song, Y Wang, Z Yu, J Li, M Wu, L Wang, J Zang, ... Journal of the American Chemical Society 132 (42), 14812-14818, 2010 | 160 | 2010 |
Photoclick chemistry: a fluorogenic light-triggered in vivo ligation reaction CP Ramil, Q Lin Current opinion in chemical biology 21, 89-95, 2014 | 153 | 2014 |
Synthesis of cell-permeable stapled peptide dual inhibitors of the p53-Mdm2/Mdmx interactions via photoinduced cycloaddition MM Madden, A Muppidi, Z Li, X Li, J Chen, Q Lin Bioorganic & medicinal chemistry letters 21 (5), 1472-1475, 2011 | 132 | 2011 |
Rapid, photoactivatable turn-on fluorescent probes based on an intramolecular photoclick reaction Z Yu, LY Ho, Q Lin Journal of the American Chemical Society 133 (31), 11912-11915, 2011 | 131 | 2011 |