The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans GTEx Consortium, KG Ardlie, DS Deluca, AV Segrè, TJ Sullivan, ... Science 348 (6235), 648-660, 2015 | 4605 | 2015 |
Artificial intelligence: A powerful paradigm for scientific research Y Xu, X Liu, X Cao, C Huang, E Liu, S Qian, X Liu, Y Wu, F Dong, CW Qiu, ... The Innovation 2 (4), 2021 | 589 | 2021 |
Effect of predicted protein-truncating genetic variants on the human transcriptome MA Rivas, M Pirinen, DF Conrad, M Lek, EK Tsang, KJ Karczewski, ... Science 348 (6235), 666-669, 2015 | 342 | 2015 |
Human pancreatic β cell lncRNAs control cell-specific regulatory networks I Akerman, Z Tu, A Beucher, DMY Rolando, C Sauty-Colace, M Benazra, ... Cell metabolism 25 (2), 400-411, 2017 | 229 | 2017 |
Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases J Yang, T Huang, F Petralia, Q Long, B Zhang, C Argmann, Y Zhao, ... Scientific reports 5 (1), 1-16, 2015 | 216* | 2015 |
Integrative random forest for gene regulatory network inference F Petralia, P Wang, J Yang, Z Tu Bioinformatics 31 (12), i197-i205, 2015 | 180 | 2015 |
Sharing and specificity of co-expression networks across 35 human tissues E Pierson, GTEx Consortium, D Koller, A Battle, S Mostafavi PLoS computational biology 11 (5), e1004220, 2015 | 176 | 2015 |
Prediction of HER2-positive breast cancer recurrence and metastasis risk from histopathological images and clinical information via multimodal deep learning J Yang, J Ju, L Guo, B Ji, S Shi, Z Yang, S Gao, X Yuan, G Tian, Y Liang, ... Computational and structural biotechnology journal 20, 333-342, 2022 | 123 | 2022 |
Identify key sequence features to improve CRISPR sgRNA efficacy L Chen, S Wang, YH Zhang, J Li, ZH Xing, J Yang, T Huang, YD Cai IEEE Access 5, 26582-26590, 2017 | 105 | 2017 |
CMF-Impute: an accurate imputation tool for single-cell RNA-seq data J Xu, L Cai, B Liao, W Zhu, JL Yang Bioinformatics 36 (10), 3139-3147, 2020 | 98 | 2020 |
Evaluating DNA methylation, gene expression, somatic mutation, and their combinations in inferring tumor tissue-of-origin H Liu, C Qiu, B Wang, P Bing, G Tian, X Zhang, J Ma, B He, J Yang Frontiers in cell and developmental biology 9, 619330, 2021 | 93 | 2021 |
A weighted bilinear neural collaborative filtering approach for drug repositioning Y Meng, C Lu, M Jin, J Xu, X Zeng, J Yang Briefings in Bioinformatics, bbab581, 2022 | 85 | 2022 |
Using sequence data to infer the antigenicity of influenza virus H Sun, J Yang, T Zhang, LP Long, K Jia, G Yang, RJ Webby, XF Wan MBio 4 (4), 10.1128/mbio. 00230-13, 2013 | 83 | 2013 |
An improved anticancer drug-response prediction based on an ensemble method integrating matrix completion and ridge regression C Liu, D Wei, J Xiang, F Ren, L Huang, J Lang, G Tian, Y Li, J Yang Molecular Therapy-Nucleic Acids 21, 676-686, 2020 | 80 | 2020 |
TOOme: a novel computational framework to infer cancer tissue-of-origin by integrating both gene mutation and expression B He, J Lang, B Wang, X Liu, Q Lu, J He, W Gao, P Bing, G Tian, J Yang Frontiers in bioengineering and biotechnology 8, 394, 2020 | 79 | 2020 |
Immunomodulatory activity of a novel polysaccharide from Lonicera japonica in immunosuppressed mice induced by cyclophosphamide X Zhou, Q Dong, X Kan, L Peng, X Xu, Y Fang, J Yang PloS one 13 (10), e0204152, 2018 | 79 | 2018 |
A machine learning framework to trace tumor tissue-of-origin of 13 types of cancer based on DNA somatic mutation B He, C Dai, J Lang, P Bing, G Tian, B Wang, J Yang Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (11), 165916, 2020 | 62 | 2020 |
Global network random walk for predicting potential human lncRNA-disease associations C Gu, B Liao, X Li, L Cai, Z Li, K Li, J Yang Scientific reports 7 (1), 12442, 2017 | 61 | 2017 |
A systematic study on drug-response associated genes using baseline gene expressions of the Cancer Cell Line Encyclopedia X Liu, J Yang, Y Zhang, Y Fang, F Wang, J Wang, X Zheng, J Yang Scientific reports 6 (1), 22811, 2016 | 61 | 2016 |
Computational molecular networks and network pharmacology K Ning, X Zhao, A Poetsch, WH Chen, J Yang BioMed research international 2017, 2017 | 59 | 2017 |