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Joseph Polex-Wolf
Joseph Polex-Wolf
在 novonordisk.com 的电子邮件经过验证
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Semaglutide lowers body weight in rodents via distributed neural pathways
S Gabery, CG Salinas, SJ Paulsen, J Ahnfelt-Rønne, T Alanentalo, ...
JCI insight 5 (6), 2020
4312020
The GLP-1 Analogs Liraglutide and Semaglutide Reduce Atherosclerosis in ApoE−/− and LDLr−/− Mice by a Mechanism That Includes Inflammatory Pathways
G Rakipovski, B Rolin, J Nøhr, I Klewe, KS Frederiksen, R Augustin, ...
JACC: Basic to Translational Science 3 (6), 844-857, 2018
3622018
Glucose-dependent insulinotropic polypeptide receptor-expressing cells in the hypothalamus regulate food intake
AE Adriaenssens, EK Biggs, T Darwish, J Tadross, T Sukthankar, M Girish, ...
Cell metabolism 30 (5), 987-996. e6, 2019
2552019
Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing
BYH Lam, I Cimino, J Polex-Wolf, SN Kohnke, D Rimmington, V Iyemere, ...
Molecular metabolism 6 (5), 383-392, 2017
1622017
Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome
J Polex-Wolf, BYH Lam, R Larder, J Tadross, D Rimmington, F Bosch, ...
The Journal of clinical investigation 128 (3), 960-969, 2018
1032018
Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation
R Larder, MFM Sim, P Gulati, R Antrobus, YCL Tung, D Rimmington, ...
Proceedings of the National Academy of Sciences 114 (35), 9421-9426, 2017
702017
A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing
GKC Dowsett, BYH Lam, JA Tadross, I Cimino, D Rimmington, AP Coll, ...
Molecular metabolism 53, 101240, 2021
692021
The GLP-1 analogs liraglutide and semaglutide reduce atherosclerosis in ApoE-/-and LDLr-/-mice by a mechanism that includes inflammatory pathways. JACC Basic Transl Sci. 2018 …
G Rakipovski, B Rolin, J Nøhr, I Klewe, KS Frederiksen, R Augustin, ...
Přejít k původnímu zdroji... Přejít na PubMed, 2019
392019
Thyroid hormone receptor beta in the ventromedial hypothalamus is essential for the physiological regulation of food intake and body weight
S Hameed, M Patterson, WS Dhillo, SA Rahman, Y Ma, C Holton, ...
Cell reports 19 (11), 2202-2209, 2017
382017
Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models
AC Rupp, AJ Tomlinson, AH Affinati, WT Yacawych, AM Duensing, C True, ...
The Journal of clinical investigation 133 (19), 2023
182023
Impaired prohormone processing: a grand unified theory for features of Prader-Willi syndrome?
J Polex-Wolf, GSH Yeo, S O’Rahilly
The Journal of Clinical Investigation 127 (1), 98-99, 2017
172017
Semaglutide lowers body weight in rodents via distributed neural pathways. JCI Insight 5 (6)
S Gabery, CG Salinas, SJ Paulsen, J Ahnfelt-Ronne, T Alanentalo, ...
162020
Human HYPOMAP: A comprehensive spatio-cellular map of the human hypothalamus
JA Tadross, L Steuernagel, GKC Dowsett, KA Kentistou, S Lundh, ...
BioRxiv, 2023.09. 15.557967, 2023
52023
A lipopolysaccharide mouse model mirrors neuroinflammatory transcriptional signatures of human Alzheimer’s disease, and the Glucagon‐Like Peptide‐1 receptor agonist semaglutide …
MQ Ludwig, DM Belmont‐Rausch, MA Bentsen, A Secher, SAN Hansen, ...
Alzheimer's & Dementia 18, e063862, 2022
42022
Liraglutide impacts iron homeostasis in a murine model of hereditary hemochromatosis
N Bozadjieva-Kramer, JH Shin, NB Blok, C Jain, NK Das, J Polex-Wolf, ...
Endocrinology 165 (9), bqae090, 2024
12024
Loss and gain of function experiments implicate TMEM18 as a mediator of the strong association between genetic variants at human Chromosome 2p25. 3 and obesity
R Larder, MF Michelle Sim, P Gulati, R Antrobus, YC Loraine Tung, ...
bioRxiv, 122853, 2017
12017
Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist
J Polex-Wolf, K Deibler, WFJ Hogendorf, S Bau, T Glendorf, CE Stidsen, ...
Science Translational Medicine 16 (776), eadk4908, 2024
2024
A Lipopolysaccharide Mouse Model Mirrors Neuroinflammatory Transcriptional Signatures of Human AD, and the Glucagon-Like Peptide-1 Receptor Agonist Semaglutide Attenuates …
MQ Ludwig, DM Belmont-Rausch, A Secher, MA Bentsen, SN Hansen, ...
Neurology 100 (17_supplement_2), 3731, 2023
2023
Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight Hameed, S., Patterson, M., Dhillo …
C Holton, A Gogakos, GSH Yeo, BYH Lam, J Polex-Wolf, W Fenske, ...
2017
The Neural Correlates of Priming Specificity: Age-Related Changes in Visual Object Priming for Multiple Presentations of Similar Items
J Polex Wolf
2011
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