| SIRT1 is downregulated by autophagy in senescence and ageing C Xu, L Wang, P Fozouni, G Evjen, V Chandra, J Jiang, C Lu, M Nicastri, ... Nature cell biology 22 (10), 1170-1179, 2020 | 407 | 2020 |
| PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer VW Rebecca, MC Nicastri, C Fennelly, CI Chude, JS Barber-Rotenberg, ... Cancer discovery 9 (2), 220-229, 2019 | 202 | 2019 |
| A unified approach to targeting the lysosome's degradative and growth signaling roles VW Rebecca, MC Nicastri, N McLaughlin, C Fennelly, Q McAfee, ... Cancer discovery 7 (11), 1266-1283, 2017 | 168 | 2017 |
| Targeting quiescent leukemic stem cells using second generation autophagy inhibitors P Baquero, A Dawson, A Mukhopadhyay, EM Kuntz, R Mitchell, ... Leukemia 33 (4), 981-994, 2019 | 123 | 2019 |
| Synthesis of sterically hindered primary amines by concurrent tandem photoredox catalysis MC Nicastri, D Lehnherr, Y Lam, DA DiRocco, T Rovis Journal of the American Chemical Society 142 (2), 987-998, 2020 | 107 | 2020 |
| Electrochemical synthesis of hindered primary and secondary amines via proton-coupled electron transfer D Lehnherr, Y Lam, MC Nicastri, J Liu, JA Newman, EL Regalado, ... Journal of the American Chemical Society 142 (1), 468-478, 2019 | 103 | 2019 |
| PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma G Sharma, R Ojha, E Noguera-Ortega, VW Rebecca, J Attanasio, S Liu, ... JCI insight 5 (17), 2020 | 62 | 2020 |
| Internal disulfide bond acts as a switch for intein activity MC Nicastri, K Xega, L Li, J Xie, C Wang, RJ Linhardt, JN Reitter, KV Mills Biochemistry 52 (34), 5920-5927, 2013 | 38 | 2013 |
| ATG5 mediates a positive feedback loop between Wnt signaling and autophagy in melanoma A Ndoye, A Budina-Kolomets, CH Kugel III, MR Webster, A Kaur, ... Cancer research 77 (21), 5873-5885, 2017 | 37 | 2017 |
| Salt-Dependent Conditional Protein Splicing of an Intein from Halobacterium salinarum JN Reitter, CE Cousin, MC Nicastri, MV Jaramillo, KV Mills Biochemistry 55 (9), 1279-1282, 2016 | 36 | 2016 |
| ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells S Piao, R Ojha, VW Rebecca, A Samanta, X Ma, Q Mcafee, MC Nicastri, ... Autophagy 13 (12), 2056-2071, 2017 | 28 | 2017 |
| Dimeric quinacrines as chemical tools to identify PPT1, a new regulator of autophagy in cancer cells MC Nicastri, VW Rebecca, RK Amaravadi, JD Winkler Molecular & cellular oncology 5 (1), e1395504, 2018 | 26 | 2018 |
| PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer. Cancer Discov. 2019; 9 (2): 220–229. doi: 10.1158/2159-8290 VW Rebecca, MC Nicastri, C Fennelly, CI Chude, JS Barber-Rotenberg, ... CD-18-0706.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 9 | |
| A unified approach to targeting the lysosome’s degradative and growth signaling roles. Cancer Discov. 2017; 7 (11): 1266–1283. doi: 10.1158/2159-8290 VW Rebecca, M Nicastri, N McLaughlin, C Fennelly, Q McAfee, A Roughe CD-17-0741.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 7 | |
| PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma. G Sharma, R Ojha, E Noguera-Ortega, VW Rebecca, J Attanasio, S Liu, ... JCI insight 7 (20), e165688-e165688, 2022 | 2 | 2022 |
| Design, Synthesis, and Characterization of Dimeric Lysosomal Inhibitors and Their Effect on Cancer Biology MC Nicastri University of Pennsylvania, 2018 | 2 | 2018 |
| Conditional protein splicing of inteins with a non‐canonical C‐terminal glutamine MC Nicastri, K Xega, JN Reitter, KV Mills The FASEB Journal 26, 959.1-959.1, 2012 | 1 | 2012 |
| Corrigendum: PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma (JCI Insight (2020) 5: 17 (e133225 G Sharma, R Ojha, E Noguera-Ortega, VW Rebecca, J Attanasio, S Liu, ... JCI Insight 7 (20), e165688, 2022 | | 2022 |
| Targeting quiescent leukemic stem cells using second generation autophagy inhibitors P Baquero Valls, A Dawson, A Mukhopadhyay, EM Kuntz, R Mitchell, ... | | 2019 |
| Synthesis of dimeric lysosomal inhibitors and their evaluation as anticancer agents M Nicastri, J Winkler, R Amaravadi, V Rebecca ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
