Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions JA Roberts, MH Abdul-Aziz, J Lipman, JW Mouton, AA Vinks, TW Felton, ... The Lancet infectious diseases 14 (6), 498-509, 2014 | 954 | 2014 |
An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units G Wong, A Brinkman, RJ Benefield, M Carlier, JJ De Waele, N El Helali, ... Journal of antimicrobial chemotherapy 69 (5), 1416-1423, 2014 | 252 | 2014 |
International Society of Anti-Infective Pharmacology and the Pharmacokinetics and Pharmacodynamics Study Group of the European Society of Clinical Microbiology and Infectious … JA Roberts, MH Abdul-Aziz, J Lipman, JW Mouton, AA Vinks, TW Felton, ... Lancet Infect Dis 14 (6), 498-509, 2014 | 178 | 2014 |
Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial S Hagel, F Bach, T Brenner, H Bracht, A Brinkmann, T Annecke, A Hohn, ... Intensive Care Medicine 48 (3), 311-321, 2022 | 134 | 2022 |
Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill patients: a … DC Richter, O Frey, A Röhr, JA Roberts, A Köberer, T Fuchs, ... Infection 47, 1001-1011, 2019 | 86 | 2019 |
In vitro removal of anti-infective agents by a novel cytokine adsorbent system C König, AC Röhr, OR Frey, A Brinkmann, JA Roberts, D Wichmann, ... The International Journal of Artificial Organs 42 (2), 57-64, 2019 | 77 | 2019 |
Adverse effects in a newborn infant breast-fed by a mother treated with doxepin OR Frey, P Scheidt, AI von Brenndorff Annals of Pharmacotherapy 33 (6), 690-693, 1999 | 76 | 1999 |
Cerebrospinal fluid penetration of meropenem in neurocritical care patients with proven or suspected ventriculitis: a prospective observational study U Blassmann, AC Roehr, OR Frey, C Vetter-Kerkhoff, N Thon, W Hope, ... Critical Care 20, 1-9, 2016 | 75 | 2016 |
Development of a dosing nomogram for continuous-infusion meropenem in critically ill patients based on a validated population pharmacokinetic model IK Minichmayr, JA Roberts, OR Frey, AC Roehr, C Kloft, A Brinkmann Journal of Antimicrobial Chemotherapy 73 (5), 1330-1339, 2018 | 69 | 2018 |
What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients? AS Alobaid, A Brinkmann, OR Frey, AC Roehr, S Luque, S Grau, G Wong, ... Journal of Antimicrobial Chemotherapy 71 (3), 696-702, 2016 | 48 | 2016 |
Population pharmacokinetics of meropenem in elderly patients: dosing simulations based on renal function M Usman, OR Frey, G Hempel European journal of clinical pharmacology 73, 333-342, 2017 | 47 | 2017 |
Therapeutic drug monitoring-based dose optimisation of piperacillin/tazobactam to improve outcome in patients with sepsis (TARGET): a prospective, multi-centre, randomised … S Hagel, S Fiedler, A Hohn, A Brinkmann, OR Frey, H Hoyer, ... Trials 20, 1-10, 2019 | 46 | 2019 |
Challenges and potential solutions–individualised antibiotic dosing at the bedside for critically ill patients: a structured review JA Roberts, MMHA Aziz, J Lipman, JW Mouton, AA Vinks, TW Felton, ... The Lancet. Infectious Diseases 14 (6), 498, 2014 | 45 | 2014 |
Polyethylene vials of calcium gluconate reduce aluminum contamination of TPN OR Frey, L Maier Annals of Pharmacotherapy 34 (6), 811-812, 2000 | 38 | 2000 |
Linezolid in liver failure: exploring the value of the maximal liver function capacity (LiMAx) test in a pharmacokinetic pilot study SG Wicha, OR Frey, AC Roehr, J Pratschke, M Stockmann, R Alraish, ... International Journal of Antimicrobial Agents 50 (4), 557-563, 2017 | 36 | 2017 |
Anti-infective drugs during continuous hemodialysis–using the bench to learn what to do at the bedside AC Roehr, OR Frey, A Koeberer, T Fuchs, JA Roberts, A Brinkmann The International Journal of Artificial Organs 38 (1), 17-22, 2015 | 30 | 2015 |
Decreased linezolid serum concentrations in three critically ill patients: clinical case studies of a potential drug interaction between linezolid and rifampicin U Blassmann, AC Roehr, OR Frey, A Koeberer, J Briegel, V Huge, ... Pharmacology 98 (1-2), 51-55, 2016 | 27 | 2016 |
Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis C König, S Braune, JA Roberts, A Nierhaus, OM Steinmetz, M Baehr, ... Journal of Antimicrobial Chemotherapy 72 (5), 1433-1440, 2017 | 26 | 2017 |
Therapeutisches drug monitoring und individualisierte Dosierung von Antibiotika bei der Sepsis A Brinkmann, AC Röhr, A Köberer, T Fuchs, J Preisenberger, WA Krüger, ... Medizinische Klinik-Intensivmedizin und Notfallmedizin 113 (2), 82-93, 2018 | 25 | 2018 |
CSF penetration of vancomycin in critical care patients with proven or suspected ventriculitis: a prospective observational study U Blassmann, W Hope, AC Roehr, OR Frey, C Vetter-Kerkhoff, N Thon, ... Journal of Antimicrobial Chemotherapy 74 (4), 991-996, 2019 | 24 | 2019 |