Auto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2 C Tan, PJ Dlugosz, J Peng, Z Zhang, SM Lapolla, SM Plafker, ... Journal of Biological Chemistry 281 (21), 14764-14775, 2006 | 209 | 2006 |
High dietary fat selectively increases catalase expression within cardiac mitochondria PM Rindler, SM Plafker, LI Szweda, M Kinter Journal of Biological Chemistry 288 (3), 1979-1990, 2013 | 188 | 2013 |
Mechanisms for countering oxidative stress and damage in retinal pigment epithelium SM Plafker, GB O'Mealey, LI Szweda International review of cell and molecular biology 298, 135-177, 2012 | 143 | 2012 |
Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import SM Plafker, KS Plafker, AM Weissman, IG Macara The Journal of cell biology 167 (4), 649-659, 2004 | 124 | 2004 |
Human cytomegalovirus capsid assembly protein precursor (pUL80. 5) interacts with itself and with the major capsid protein (pUL86) through two different domains LJ Wood, MK Baxter, SM Plafker, W Gibson Journal of virology 71 (1), 179-190, 1997 | 114 | 1997 |
Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2 SM Plafker, IG Macara The EMBO journal 19 (20), 5502-5513, 2000 | 95 | 2000 |
Human papillomavirus 16 E5 induces bi-nucleated cell formation by cell–cell fusion L Hu, K Plafker, V Vorozhko, RE Zuna, MH Hanigan, GJ Gorbsky, ... Virology 384 (1), 125-134, 2009 | 93 | 2009 |
A PGAM5–KEAP1–Nrf2 complex is required for stress-induced mitochondrial retrograde trafficking GB O'Mealey, KS Plafker, WL Berry, R Janknecht, JY Chan, SM Plafker Journal of cell science 130 (20), 3467-3480, 2017 | 92 | 2017 |
Oxidative stress and the Nrf2 anti-oxidant transcription factor in age-related macular degeneration ML Lambros, SM Plafker Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 67-72, 2016 | 89 | 2016 |
The ubiquitin-conjugating enzyme UbcM2 can regulate the stability and activity of the antioxidant transcription factor Nrf2 KS Plafker, L Nguyen, M Barneche, S Mirza, D Crawford, SM Plafker Journal of biological chemistry 285 (30), 23064-23074, 2010 | 81 | 2010 |
Interaction with CREB binding protein modulates the activities of Nrf2 and NF-κB in cystic fibrosis airway epithelial cells AG Ziady, A Sokolow, S Shank, D Corey, R Myers, S Plafker, TJ Kelley American Journal of Physiology-Lung Cellular and Molecular Physiology 302 …, 2012 | 76 | 2012 |
Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis CM Larabee, S Desai, A Agasing, C Georgescu, JD Wren, RC Axtell, ... Molecular vision 22, 1503, 2016 | 72 | 2016 |
Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11 SM Plafker, IG Macara Molecular and cellular biology 22 (4), 1266-1275, 2002 | 71 | 2002 |
Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission GB O'Mealey, WL Berry, SM Plafker Redox biology 11, 103-110, 2017 | 66 | 2017 |
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes E Pick, OS Lau, T Tsuge, S Menon, Y Tong, N Dohmae, SM Plafker, ... Molecular and cellular biology 27 (13), 4708-4719, 2007 | 63 | 2007 |
Cytomegalovirus assembly protein precursor and proteinase precursor contain two nuclear localization signals that mediate their own nuclear translocation and that of the major … SM Plafker, W Gibson Journal of virology 72 (10), 7722-7732, 1998 | 61 | 1998 |
Deciphering mutant ELOVL4 activity in autosomal-dominant Stargardt macular dystrophy S Logan, MP Agbaga, MD Chan, N Kabir, NA Mandal, RS Brush, ... Proceedings of the National Academy of Sciences 110 (14), 5446-5451, 2013 | 60 | 2013 |
The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein M Chen, DG Nowak, N Narula, B Robinson, K Watrud, A Ambrico, ... Journal of Cell Biology 216 (3), 641-656, 2017 | 44 | 2017 |
Clinically approved CFTR modulators rescue Nrf2 dysfunction in cystic fibrosis airway epithelia DC Borcherding, ME Siefert, S Lin, J Brewington, H Sadek, JP Clancy, ... The Journal of clinical investigation 129 (8), 3448-3463, 2019 | 41 | 2019 |
The ubiquitin-conjugating enzyme UBE2E3 and its import receptor importin-11 regulate the localization and activity of the antioxidant transcription factor NRF2 KS Plafker, SM Plafker Molecular biology of the cell 26 (2), 327-338, 2015 | 35 | 2015 |