Role of T-bet in commitment of TH1 cells before IL-12-dependent selection AC Mullen, FA High, AS Hutchins, HW Lee, AV Villarino, DM Livingston, ... Science 292 (5523), 1907-1910, 2001 | 1171 | 2001 |
Hlx is induced by and genetically interacts with T-bet to promote heritable TH1 gene induction AC Mullen, AS Hutchins, FA High, HW Lee, KJ Sykes, LA Chodosh, ... Nature immunology 3 (7), 652-658, 2002 | 426 | 2002 |
Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development FA High, MM Lu, WS Pear, KM Loomes, KH Kaestner, JA Epstein Proceedings of the National Academy of Sciences 105 (6), 1955-1959, 2008 | 378 | 2008 |
The multifaceted role of Notch in cardiac development and disease FA High, JA Epstein Nature Reviews Genetics 9 (1), 49-61, 2008 | 368 | 2008 |
An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation FA High, M Zhang, A Proweller, LL Tu, MS Parmacek, WS Pear, ... The Journal of clinical investigation 117 (2), 353-363, 2007 | 302 | 2007 |
Gene silencing quantitatively controls the function of a developmental trans-activator AS Hutchins, AC Mullen, HW Lee, KJ Sykes, FA High, BD Hendrich, ... Molecular cell 10 (1), 81-91, 2002 | 272 | 2002 |
Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives KA Engleka, AD Gitler, M Zhang, DD Zhou, FA High, JA Epstein Developmental biology 280 (2), 396-406, 2005 | 255 | 2005 |
Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development FA High, R Jain, JZ Stoller, NB Antonucci, MM Lu, KM Loomes, ... The Journal of clinical investigation 119 (7), 1986-1996, 2009 | 219 | 2009 |
Notch activation of Jagged1 contributes to the assembly of the arterial wall LJ Manderfield, FA High, KA Engleka, F Liu, L Li, S Rentschler, JA Epstein Circulation 125 (2), 314-323, 2012 | 195 | 2012 |
Nuclear repositioning marks the selective exclusion of lineage‐inappropriate transcription factor loci during T helper cell differentiation SL Hewitt, FA High, SL Reiner, AG Fisher, M Merkenschlager European journal of immunology 34 (12), 3604-3613, 2004 | 167 | 2004 |
Congenital diaphragmatic hernia overview M Longoni, BR Pober, FA High | 162 | 2020 |
Induction of Cytotoxic T Lymphocyte Antigen 4 (Ctla-4) Restricts Clonal Expansion of Helper T Cells AM Doyle, AC Mullen, AV Villarino, AS Hutchins, FA High, HW Lee, ... The Journal of experimental medicine 194 (7), 893-902, 2001 | 134 | 2001 |
Mutations in KCNK4 that affect gating cause a recognizable neurodevelopmental syndrome CK Bauer, P Calligari, FC Radio, V Caputo, ML Dentici, N Falah, F High, ... The American Journal of Human Genetics 103 (4), 621-630, 2018 | 100 | 2018 |
De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders H Qi, L Yu, X Zhou, J Wynn, H Zhao, Y Guo, N Zhu, A Kitaygorodsky, ... PLoS genetics 14 (12), e1007822, 2018 | 94 | 2018 |
Cell cycle controlling the silencing and functioning of mammalian activators AC Mullen, AS Hutchins, AV Villarino, HW Lee, FA High, N Cereb, ... Current Biology 11 (21), 1695-1699, 2001 | 92 | 2001 |
N-cadherin is required for neural crest remodeling of the cardiac outflow tract Y Luo, FA High, JA Epstein, GL Radice Developmental biology 299 (2), 517-528, 2006 | 90 | 2006 |
Cutting edge: innate production of IFN-γ by NK cells is independent of epigenetic modification of the IFN-γ promoter CM Tato, GA Martins, FA High, CB DiCioccio, SL Reiner, CA Hunter The Journal of Immunology 173 (3), 1514-1517, 2004 | 81 | 2004 |
Lysosomal storage and albinism due to effects of a de novo CLCN7 variant on lysosomal acidification ER Nicoli, MR Weston, M Hackbarth, A Becerril, A Larson, WM Zein, ... The American Journal of Human Genetics 104 (6), 1127-1138, 2019 | 74 | 2019 |
De novo variants in the ATPase module of MORC2 cause a neurodevelopmental disorder with growth retardation and variable craniofacial dysmorphism MJG Sacoto, IA Tchasovnikarova, E Torti, C Forster, EH Andrew, I Anselm, ... The American Journal of Human Genetics 107 (2), 352-363, 2020 | 73 | 2020 |
Truncating variants in NAA15 are associated with variable levels of intellectual disability, autism spectrum disorder, and congenital anomalies H Cheng, AV Dharmadhikari, S Varland, N Ma, D Domingo, R Kleyner, ... The American Journal of Human Genetics 102 (5), 985-994, 2018 | 70 | 2018 |