Pre-conception folic acid and multivitamin supplementation for the primary and secondary prevention of neural tube defects and other folic acid-sensitive congenital anomalies RD Wilson, F Audibert, JA Brock, J Carroll, L Cartier, A Gagnon, ... Journal of Obstetrics and Gynaecology Canada 37 (6), 534-549, 2015 | 321 | 2015 |
Mechanisms of oocyte aneuploidy associated with advanced maternal age M Mikwar, AJ MacFarlane, F Marchetti Mutation Research/Reviews in Mutation Research 785, 108320, 2020 | 203 | 2020 |
Vitamin B-12 and homocysteine status in a folate-replete population: results from the Canadian Health Measures Survey AJ MacFarlane, LS Greene-Finestone, Y Shi The American journal of clinical nutrition 94 (4), 1079-1087, 2011 | 181 | 2011 |
Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice AJ MacFarlane, X Liu, CA Perry, P Flodby, RH Allen, SP Stabler, ... Journal of Biological Chemistry 283 (38), 25846-25853, 2008 | 162 | 2008 |
Options for basing Dietary Reference Intakes (DRIs) on chronic disease endpoints: report from a joint US-/Canadian-sponsored working group EA Yetley, AJ MacFarlane, LS Greene-Finestone, C Garza, JD Ard, ... The American journal of clinical nutrition 105 (1), 249S-285S, 2017 | 159 | 2017 |
Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop P Maruvada, PJ Stover, JB Mason, RL Bailey, CD Davis, MS Field, ... The American journal of clinical nutrition 112 (5), 1390-1403, 2020 | 136 | 2020 |
Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation L Ly, D Chan, M Aarabi, M Landry, NA Behan, AJ MacFarlane, J Trasler MHR: Basic science of reproductive medicine 23 (7), 461-477, 2017 | 123 | 2017 |
High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism M Aarabi, MC San Gabriel, D Chan, NA Behan, M Caron, T Pastinen, ... Human molecular genetics 24 (22), 6301-6313, 2015 | 121 | 2015 |
A type 1 diabetes-related protein from wheat (Triticum aestivum): cDNA clone of a wheat storage globulin, Glb1, linked to islet damage AJ MacFarlane, KM Burghardt, J Kelly, T Simell, O Simell, I Altosaar, ... Journal of Biological Chemistry 278 (1), 54-63, 2003 | 121 | 2003 |
Epigenetics: deciphering how environmental factors may modify autoimmune type 1 diabetes AJ MacFarlane, A Strom, FW Scott Mammalian Genome 20 (9), 624-632, 2009 | 97 | 2009 |
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism AJ MacFarlane, CA Perry, HH Girnary, D Gao, RH Allen, SP Stabler, ... Journal of biological chemistry 284 (3), 1533-1539, 2009 | 96 | 2009 |
Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA AJ MacFarlane, DD Anderson, P Flodby, CA Perry, RH Allen, SP Stabler, ... Journal of Biological Chemistry 286 (51), 44015-44022, 2011 | 86 | 2011 |
Gestational exposures to phthalates and folic acid, and autistic traits in Canadian children Y Oulhote, B Lanphear, JM Braun, GM Webster, TE Arbuckle, T Etzel, ... Environmental health perspectives 128 (2), 027004, 2020 | 78 | 2020 |
Periconceptional intake of folic acid among low-risk women in Canada: summary of a workshop aiming to align prenatal folic acid supplement composition with current expert … Y Lamers, AJ MacFarlane, DL O'Connor, B Fontaine-Bisson The American journal of clinical nutrition 108 (6), 1357-1368, 2018 | 69 | 2018 |
Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population JWR Zinck, M de Groh, AJ MacFarlane The American journal of clinical nutrition 101 (6), 1295-304, 2015 | 69 | 2015 |
B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke NM Jadavji, JT Emmerson, AJ MacFarlane, WG Willmore, PD Smith Neurobiology of disease 103, 89-100, 2017 | 64 | 2017 |
Total folate and unmetabolized folic acid in the breast milk of a cross-section of Canadian women R Page, A Robichaud, TE Arbuckle, WD Fraser, AJ MacFarlane The American Journal of Clinical Nutrition 105 (5), 1101-1109, 2017 | 61 | 2017 |
Investigating the effects of dietary folic acid on sperm count, DNA damage and mutation in Balb/c mice BG Swayne, A Kawata, NA Behan, A Williams, MG Wade, AJ MacFarlane, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 737 (1 …, 2012 | 60 | 2012 |
Convergence of genetic, nutritional and inflammatory factors in gastrointestinal cancers AJ MacFarlane, PJ Stover Nutrition reviews 65 (suppl_3), S157-S166, 2007 | 60 | 2007 |
Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apcmin-mediated intestinal cancer risk AJ MacFarlane, CA Perry, MF McEntee, DM Lin, PJ Stover Cancer research 71 (6), 2098-2107, 2011 | 59 | 2011 |