Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy RC Laker, JC Drake, RJ Wilson, VA Lira, BM Lewellen, KA Ryall, ... Nature communications 8 (1), 548, 2017 | 410 | 2017 |
Modeling β-adrenergic control of cardiac myocyte contractility in silico JJ Saucerman, LL Brunton, AP Michailova, AD McCulloch Journal of Biological Chemistry 278 (48), 47997-48003, 2003 | 269 | 2003 |
Mapping macrophage polarization over the myocardial infarction time continuum AJ Mouton, KY DeLeon-Pennell, OJ Rivera Gonzalez, ER Flynn, ... Basic research in cardiology 113, 1-18, 2018 | 255 | 2018 |
Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane BM Kenwood, JL Weaver, A Bajwa, IK Poon, FL Byrne, BA Murrow, ... Molecular metabolism 3 (2), 114-123, 2014 | 242 | 2014 |
A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo RC Laker, P Xu, KA Ryall, A Sujkowski, BM Kenwood, KH Chain, ... Journal of Biological Chemistry 289 (17), 12005-12015, 2014 | 241 | 2014 |
Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes JJ Saucerman, J Zhang, JC Martin, LX Peng, AE Stenbit, RY Tsien, ... Proceedings of the National Academy of Sciences 103 (34), 12923-12928, 2006 | 180 | 2006 |
Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes JJ Saucerman, DM Bers Biophysical journal 95 (10), 4597-4612, 2008 | 179 | 2008 |
Mechanical regulation of gene expression in cardiac myocytes and fibroblasts JJ Saucerman, PM Tan, KS Buchholz, AD McCulloch, JH Omens Nature Reviews Cardiology 16 (6), 361-378, 2019 | 172 | 2019 |
Local plantar pressure relief in therapeutic footwear: design guidelines from finite element models A Erdemir, JJ Saucerman, D Lemmon, B Loppnow, B Turso, JS Ulbrecht, ... Journal of biomechanics 38 (9), 1798-1806, 2005 | 163 | 2005 |
Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP V Sample, LM DiPilato, JH Yang, Q Ni, JJ Saucerman, J Zhang Nature chemical biology 8 (4), 375-382, 2012 | 150 | 2012 |
Synergy between CaMKII substrates and β-adrenergic signaling in regulation of cardiac myocyte Ca2+ handling AR Soltis, JJ Saucerman Biophysical journal 99 (7), 2038-2047, 2010 | 150 | 2010 |
Proarrhythmic consequences of a KCNQ1 AKAP-binding domain mutation: computational models of whole cells and heterogeneous tissue JJ Saucerman, SN Healy, ME Belik, JL Puglisi, AD McCulloch Circulation research 95 (12), 1216-1224, 2004 | 143 | 2004 |
Endotoxin depresses heart rate variability in mice: cytokine and steroid effects KD Fairchild, JJ Saucerman, LL Raynor, JA Sivak, Y Xiao, DE Lake, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2009 | 132 | 2009 |
Network reconstruction and systems analysis of cardiac myocyte hypertrophy signaling KA Ryall, DO Holland, KA Delaney, MJ Kraeutler, AJ Parker, ... Journal of Biological Chemistry 287 (50), 42259-42268, 2012 | 94 | 2012 |
Modeling cardiac β-adrenergic signaling with normalized-Hill differential equations: comparison with a biochemical model MJ Kraeutler, AR Soltis, JJ Saucerman BMC systems biology 4, 1-12, 2010 | 94 | 2010 |
Mechanistic systems models of cell signaling networks: a case study of myocyte adrenergic regulation JJ Saucerman, AD McCulloch Progress in biophysics and molecular biology 85 (2-3), 261-278, 2004 | 89 | 2004 |
Cardiac β‐adrenergic signaling: From subcellular microdomains to heart failure JJ Saucerman, AD McCULLOCH Annals of the New York Academy of Sciences 1080 (1), 348-361, 2006 | 85 | 2006 |
Calmodulin binding proteins provide domains of local Ca2+ signaling in cardiac myocytes JJ Saucerman, DM Bers Journal of molecular and cellular cardiology 52 (2), 312-316, 2012 | 81 | 2012 |
Mechanisms of cyclic AMP compartmentation revealed by computational models JJ Saucerman, EC Greenwald, R Polanowska-Grabowska The Journal of general physiology 143 (1), 39-48, 2014 | 78 | 2014 |
A computational model of cardiac fibroblast signaling predicts context-dependent drivers of myofibroblast differentiation AC Zeigler, WJ Richardson, JW Holmes, JJ Saucerman Journal of molecular and cellular cardiology 94, 72-81, 2016 | 75 | 2016 |