Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes M Mirzaei, VB Gupta, JM Chick, TM Greco, Y Wu, N Chitranshi, RV Wall, ... Scientific reports 7 (1), 12685, 2017 | 133 | 2017 |
Amyloid β accumulation and inner retinal degenerative changes in Alzheimer’s disease transgenic mouse VK Gupta, N Chitranshi, VB Gupta, M Golzan, Y Dheer, R Vander Wall, ... Neuroscience letters 623, 52-56, 2016 | 121 | 2016 |
Demyelination precedes axonal loss in the transneuronal spread of human neurodegenerative disease Y You, C Joseph, C Wang, V Gupta, S Liu, C Yiannikas, BE Chua, ... Brain 142 (2), 426-442, 2019 | 97 | 2019 |
Glaucoma pathogenesis and neurotrophins: focus on the molecular and genetic basis for therapeutic prospects N Chitranshi, Y Dheer, M Abbasi, Y You, SL Graham, V Gupta Current Neuropharmacology 16 (7), 1018-1035, 2018 | 94 | 2018 |
One protein, multiple pathologies: multifaceted involvement of amyloid β in neurodegenerative disorders of the brain and retina V Gupta, VB Gupta, N Chitranshi, S Gangoda, R Vander Wall, M Abbasi, ... Cellular and molecular life sciences 73, 4279-4297, 2016 | 72 | 2016 |
Cell cycle deficits in neurodegenerative disorders: uncovering molecular mechanisms to drive innovative therapeutic development C Joseph, AS Mangani, V Gupta, N Chitranshi, T Shen, Y Dheer, ... Aging and disease 11 (4), 946, 2020 | 68 | 2020 |
Loss of Shp2 rescues BDNF/TrkB signaling and contributes to improved retinal ganglion cell neuroprotection N Chitranshi, Y Dheer, M Mirzaei, Y Wu, GH Salekdeh, M Abbasi, V Gupta, ... Molecular Therapy 27 (2), 424-441, 2019 | 52 | 2019 |
Bexarotene modulates retinoid-X-receptor expression and is protective against neurotoxic endoplasmic reticulum stress response and apoptotic pathway activation Y Dheer, N Chitranshi, V Gupta, M Abbasi, M Mirzaei, Y You, R Chung, ... Molecular neurobiology 55, 9043-9056, 2018 | 52 | 2018 |
Upregulation of proteolytic pathways and altered protein biosynthesis underlie retinal pathology in a mouse model of Alzheimer’s disease M Mirzaei, K Pushpitha, L Deng, N Chitranshi, V Gupta, R Rajput, ... Molecular Neurobiology 56 (9), 6017-6034, 2019 | 49 | 2019 |
Amyloid β induces early changes in the ribosomal machinery, cytoskeletal organization and oxidative phosphorylation in retinal photoreceptor cells L Deng, K Pushpitha, C Joseph, V Gupta, R Rajput, N Chitranshi, Y Dheer, ... Frontiers in Molecular Neuroscience 12, 426458, 2019 | 35 | 2019 |
Glaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin V Gupta, M Mirzaei, VB Gupta, N Chitranshi, Y Dheer, R Vander Wall, ... Scientific Reports 7 (1), 8412, 2017 | 31 | 2017 |
Retinoid x receptor modulation protects against ER stress response and rescues glaucoma phenotypes in adult mice Y Dheer, N Chitranshi, V Gupta, S Sharma, K Pushpitha, M Abbasi, ... Experimental Neurology 314, 111-125, 2019 | 25 | 2019 |
Regulation of brain-derived neurotrophic factor and growth factor signaling pathways by tyrosine phosphatase Shp2 in the retina: a brief review M Abbasi, V Gupta, N Chitranshi, Y You, Y Dheer, M Mirzaei, SL Graham Frontiers in Cellular Neuroscience 12, 85, 2018 | 25 | 2018 |
PTPN11 induces endoplasmic stress and apoptosis in SH-SY5Y cells N Chitranshi, Y Dheer, V Gupta, M Abbasi, M Mirzaei, Y You, R Chung, ... Neuroscience 364, 175-189, 2017 | 25 | 2017 |
Molecular docking, dynamics, and pharmacology studies on bexarotene as an agonist of ligand‐activated transcription factors, retinoid X receptors N Chitranshi, Y Dheer, S Kumar, SL Graham, V Gupta Journal of Cellular Biochemistry 120 (7), 11745-11760, 2019 | 18 | 2019 |
Caveolin-1 ablation imparts partial protection against inner retinal injury in experimental glaucoma and reduces apoptotic activation M Abbasi, VK Gupta, N Chitranshi, VB Gupta, M Mirzaei, Y Dheer, ... Molecular neurobiology 57, 3759-3784, 2020 | 15 | 2020 |
Computational analysis unravels novel destructive single nucleotide polymorphisms in the non-synonymous region of human caveolin gene N Chitranshi, Y Dheer, R Vander Wall, V Gupta, M Abbasi, SL Graham, ... Gene Reports 6, 142-157, 2017 | 10 | 2017 |
Molecular determinants and interaction data of cyclic peptide inhibitor with the extracellular domain of TrkB receptor N Chitranshi, V Gupta, Y Dheer, V Gupta, R Vander Wall, S Graham Data in brief 6, 776-782, 2016 | 7 | 2016 |
Effects of Caveolin‐1 ablation in the inner retina under healthy and experimental glaucoma conditions M Abbasi, V Gupta, Y Dheer, C Joseph, R Vanderwall, SL Graham Acta Ophthalmologica 95, 2017 | 1 | 2017 |
Understanding the Retinoid-x-receptor biology and manipulating it as a novel strategy to protect the retina Y Dheer Macquarie University, 2022 | | 2022 |