| Structural basis for macrolactonization by the pikromycin thioesterase DL Akey, JD Kittendorf, JW Giraldes, RA Fecik, DH Sherman, JL Smith Nature chemical biology 2 (10), 537-542, 2006 | 146 | 2006 |
| Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels JW Giraldes, DL Akey, JD Kittendorf, DH Sherman, JL Smith, RA Fecik Nature Chemical Biology 2 (10), 531-536, 2006 | 108 | 2006 |
| Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin DA Hansen, CM Rath, EB Eisman, ARH Narayan, JD Kittendorf, ... Journal of the American Chemical Society 135 (30), 11232-11238, 2013 | 77 | 2013 |
| The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis JD Kittendorf, DH Sherman Bioorganic & medicinal chemistry 17 (6), 2137-2146, 2009 | 73 | 2009 |
| Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase JB Scaglione, DL Akey, R Sullivan, JD Kittendorf, CM Rath, ES Kim, ... Angewandte Chemie (International ed. in English) 49 (33), 5726, 2010 | 70 | 2010 |
| Developing tools for engineering hybrid polyketide synthetic pathways JD Kittendorf, DH Sherman Current opinion in biotechnology 17 (6), 597-605, 2006 | 58 | 2006 |
| Transglycosylation: a mechanism for RNA modification (and editing?) GA Garcia, JD Kittendorf Bioorganic chemistry 33 (3), 229-251, 2005 | 58 | 2005 |
| Synthesis and biochemical analysis of complex chain-elongation intermediates for interrogation of molecular specificity in the erythromycin and pikromycin polyketide synthases JD Mortison, JD Kittendorf, DH Sherman Journal of the American Chemical Society 131 (43), 15784-15793, 2009 | 42 | 2009 |
| Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA … YC Chen, AF Brooks, DAM Goodenough-Lashua, JD Kittendorf, ... Nucleic acids research 39 (7), 2834-2844, 2011 | 38 | 2011 |
| tRNA−Guanine Transglycosylase from Escherichia coli: Molecular Mechanism and Role of Aspartate 89 JD Kittendorf, LM Barcomb, ST Nonekowski, GA Garcia Biochemistry 40 (47), 14123-14133, 2001 | 36 | 2001 |
| Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase JD Kittendorf, BJ Beck, TJ Buchholz, W Seufert, DH Sherman Chemistry & biology 14 (8), 944-954, 2007 | 35 | 2007 |
| An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coli JD Kittendorf, T Sgraja, K Reuter, G Klebe, GA Garcia Journal of Biological Chemistry 278 (43), 42369-42376, 2003 | 22 | 2003 |
| Identification of the Rate-Determining Step of tRNA-Guanine Transglycosylase from Escherichia coli GA Garcia, SM Chervin, JD Kittendorf Biochemistry 48 (47), 11243-11251, 2009 | 19 | 2009 |
| From Hit to Lead: De Novo Design Based on Virtual Screening Hits of Inhibitors of tRNA‐Guanine Transglycosylase, a Putative Target of Shigellosis Therapy R Brenk, HD Gerber, JD Kittendorf, GA Garcia, K Reuter, G Klebe Helvetica chimica acta 86 (5), 1435-1452, 2003 | 18 | 2003 |
| NRPS/PKS hybrid enzymes and their natural products CM Rath, JB Scaglione, JD Kittendorf, DH Sherman Elsevier, 2010 | 14 | 2010 |
| Probing the intermediacy of covalent RNA enzyme complexes in RNA modification enzymes SM Chervin, JD Kittendorf, GA Garcia Methods in enzymology 425, 121-137, 2007 | 6 | 2007 |
| Polyketide biosynthesis: modular polyketide synthases TJ Buchholz, JD Kittendorf, DH Sherman Wiley Encyclopedia of Chemical Biology, 1-14, 2007 | 4 | 2007 |
| Substrate Trapping in Polyketide Synthase Thioesterase Domains: Structural Basis for Macrolactone Formation TM McCullough, V Choudhary, DL Akey, MA Skiba, SM Bernard, ... Acs Catalysis 14 (16), 12551-12563, 2024 | 3 | 2024 |
| Biosynthetic Principles in Marine Natural Product Systems DH Sherman, CM Rath, J Mortison, JB Scaglione, JD Kittendorf Handbook of Marine Natural Products; Fattorusso, E., Gerwick, WH …, 2012 | 2 | 2012 |
| Catalysis by tRNA -guanine transglycosylase from Escherichia coli JD Kittendorf University of Michigan, 2004 | 2 | 2004 |
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