Epigenetic transmission of the impact of early stress across generations TB Franklin, H Russig, IC Weiss, J Gräff, N Linder, A Michalon, S Vizi, ... Biological psychiatry 68 (5), 408-415, 2010 | 1337 | 2010 |
Protein phosphatase 1 is a molecular constraint on learning and memory D Genoux, U Haditsch, M Knobloch, A Michalon, D Storm, IM Mansuy Nature 418 (6901), 970-975, 2002 | 571 | 2002 |
Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice A Michalon, M Sidorov, TM Ballard, L Ozmen, W Spooren, JG Wettstein, ... Neuron 74 (1), 49-56, 2012 | 551 | 2012 |
NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory BJ Saab, J Georgiou, A Nath, FJS Lee, M Wang, A Michalon, F Liu, ... Neuron 63 (5), 643-656, 2009 | 236 | 2009 |
CTEP: a novel, potent, long-acting, and orally bioavailable metabotropic glutamate receptor 5 inhibitor L Lindemann, G Jaeschke, A Michalon, E Vieira, M Honer, W Spooren, ... Journal of Pharmacology and Experimental Therapeutics 339 (2), 474-486, 2011 | 130 | 2011 |
Drug discovery for autism spectrum disorder: challenges and opportunities A Ghosh, A Michalon, L Lindemann, P Fontoura, L Santarelli Nature Reviews Drug Discovery 12 (10), 777-790, 2013 | 125 | 2013 |
Chronic metabotropic glutamate receptor 5 inhibition corrects local alterations of brain activity and improves cognitive performance in fragile X mice A Michalon, A Bruns, C Risterucci, M Honer, TM Ballard, L Ozmen, ... Biological psychiatry 75 (3), 189-197, 2014 | 85 | 2014 |
Inducible and neuron‐specific gene expression in the adult mouse brain with the rtTA2S‐M2 system A Michalon, K Koshibu, K Baumgärtel, DH Spirig, IM Mansuy Genesis 43 (4), 205-212, 2005 | 69 | 2005 |
Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid P Garcia-Pavia, F Aus dem Siepen, E Donal, O Lairez, P van der Meer, ... New England Journal of Medicine, 2023 | 68 | 2023 |
A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells A Michalon, A Hagenbuch, C Huy, E Varela, B Combaluzier, T Damy, ... Nature communications 12 (1), 3142, 2021 | 48 | 2021 |
Molecular pathophysiology of fragile X-associated tremor/ataxia syndrome and perspectives for drug development T Botta-Orfila, GG Tartaglia, A Michalon The Cerebellum 15, 599-610, 2016 | 23 | 2016 |
Characterization of conformation-specific, human-derived monoclonal antibodies against TTR aggregates with potential for diagnostic and therapeutic use A Michalon, B Combaluzier, E Varela, A Hagenbuch, O Suhr, M Saraiva, ... Orphanet Journal of Rare Diseases 10 (1), 1-1, 2015 | 3 | 2015 |
Combination therapy for ttr amyloidosis A Michalon, J Grimm US Patent App. 17/924,496, 2023 | | 2023 |
Antibody-based therapy of transthyretin (ttr) amyloidosis and human-derived antibodies therefor J Grimm, A Michalon US Patent App. 17/532,292, 2022 | | 2022 |
Patient-derived amyloid xenograft non-human animal model A Michalon, J Grimm US Patent App. 17/292,107, 2021 | | 2021 |
Antibody-based therapy of transthyretin (TTR) amyloidosis and human-derived antibodies therefor J Grimm, A Michalon US Patent 11,180,545, 2021 | | 2021 |
Antibody-based therapy of transthyretin (TTR) amyloidosis and human-derived antibodies therefor J Grimm, A Michalon US Patent 10,344,080, 2019 | | 2019 |
Investigating Therapeutic Strategies for Fragile X Syndrome in Mice A Michalon, L Lindemann Genetically Modified Organisms and Genetic Engineering in Research and …, 2012 | | 2012 |
Dual approach to study the impact of glycine-mediated modulation of glutamatergic transmission on behaviour A Michalon ETH Zurich, 2005 | | 2005 |
Genetic systems for inducible and reversible gene recombination and expression in the mouse brain K Baumgärtel, A Michalon, K Koshibu, D Spirig, IM Mansuy NCCR Neural Plasticity and Repair Symposium 2005, 2005 | | 2005 |