The complexity of PRC2 subcomplexes G van Mierlo, GJC Veenstra, M Vermeulen, H Marks Trends in cell biology 29 (8), 660-671, 2019 | 206 | 2019 |
MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding M Perino, G van Mierlo, ID Karemaker, S van Genesen, M Vermeulen, ... Nature genetics 50 (7), 1002-1010, 2018 | 176 | 2018 |
PRC2. 1 and PRC2. 2 synergize to coordinate H3K27 trimethylation E Healy, M Mucha, E Glancy, DJ Fitzpatrick, E Conway, HK Neikes, ... Molecular cell 76 (3), 437-452. e6, 2019 | 162 | 2019 |
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma GL Brien, D Remillard, J Shi, ML Hemming, J Chabon, K Wynne, ... Elife 7, e41305, 2018 | 155 | 2018 |
Dynamics of gene silencing during X inactivation using allele-specific RNA-seq H Marks, HHD Kerstens, TS Barakat, E Splinter, RAM Dirks, G van Mierlo, ... Genome biology 16, 1-20, 2015 | 131 | 2015 |
In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states A Neagu, E van Genderen, I Escudero, L Verwegen, D Kurek, J Lehmann, ... Nature cell biology 22 (5), 534-545, 2020 | 104 | 2020 |
Integrative proteomic profiling reveals PRC2-dependent epigenetic crosstalk maintains ground-state pluripotency G van Mierlo, RAM Dirks, L De Clerck, AB Brinkman, M Huth, SL Kloet, ... Cell stem cell 24 (1), 123-137. e8, 2019 | 103 | 2019 |
Predicting protein condensate formation using machine learning G van Mierlo, JRG Jansen, J Wang, I Poser, SJ van Heeringen, ... Cell reports 34 (5), 2021 | 77 | 2021 |
Identification of Allobaculum mucolyticum as a novel human intestinal mucin degrader GH van Muijlwijk, G van Mierlo, PWTC Jansen, M Vermeulen, ... Gut Microbes 13 (1), 1966278, 2021 | 57 | 2021 |
Off-the-shelf proximity biotinylation for interaction proteomics I Santos-Barriopedro, G van Mierlo, M Vermeulen Nature communications 12 (1), 5015, 2021 | 38 | 2021 |
Purification and enrichment of specific chromatin loci M Gauchier, G van Mierlo, M Vermeulen, J Déjardin Nature Methods 17 (4), 380-389, 2020 | 38 | 2020 |
Two functional axes of feedback-enforced PRC2 recruitment in mouse embryonic stem cells M Perino, G van Mierlo, C Loh, SMT Wardle, DW Zijlmans, H Marks, ... Stem Cell Reports 15 (6), 1287-1300, 2020 | 29* | 2020 |
Critical role for P53 in regulating the cell cycle of ground state embryonic stem cells M Ter Huurne, T Peng, G Yi, G van Mierlo, H Marks, HG Stunnenberg Stem cell reports 14 (2), 175-183, 2020 | 28 | 2020 |
Chromatin proteomics to study epigenetics—challenges and opportunities G van Mierlo, M Vermeulen Molecular & Cellular Proteomics 20, 2021 | 25 | 2021 |
A mass spectrometry survey of chromatin‐associated proteins in pluripotency and early lineage commitment G van Mierlo, RA Wester, H Marks Proteomics 19 (14), 1900047, 2019 | 17 | 2019 |
A cyclin-dependent kinase-mediated phosphorylation switch of disordered protein condensation JM Valverde, G Dubra, M Phillips, A Haider, C Elena-Real, A Fournet, ... Nature Communications 14 (1), 6316, 2023 | 15* | 2023 |
Chromatin modules and their implication in genomic organization and gene regulation G van Mierlo, O Pushkarev, JF Kribelbauer, B Deplancke Trends in Genetics 39 (2), 140-153, 2023 | 13 | 2023 |
Direct in vivo activation of T cells with nanosized immunofilaments inhibits tumor growth and metastasis L Weiss, J Weiden, Y Dölen, EM Grad, EAW van Dinther, M Schluck, ... Acs Nano 17 (13), 12101-12117, 2023 | 10 | 2023 |
Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states RAM Dirks, G Van Mierlo, HHD Kerstens, AS Bernardo, J Kobolák, I Bock, ... Epigenetics & Chromatin 12, 1-21, 2019 | 10 | 2019 |
Quantitative subcellular proteomics using SILAC reveals enhanced metabolic buffering in the pluripotent ground state G van Mierlo, RA Wester, H Marks Stem Cell Research 33, 135-145, 2018 | 8 | 2018 |