Perfused multiwell plate for 3D liver tissue engineering K Domansky, W Inman, J Serdy, A Dash, MHM Lim, LG Griffith Lab on a Chip 10 (1), 51-58, 2010 | 529 | 2010 |
Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: a randomized clinical trial SG Kelsen, IO Agache, W Soong, E Israel, GL Chupp, DS Cheung, ... Journal of allergy and clinical immunology 148 (3), 790-798, 2021 | 226 | 2021 |
Liver tissue engineering in the evaluation of drug safety A Dash, W Inman, K Hoffmaster, S Sevidal, J Kelly, RS Obach, LG Griffith, ... Expert opinion on drug metabolism & toxicology 5 (10), 1159-1174, 2009 | 192 | 2009 |
Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis RE Feaver, BK Cole, MJ Lawson, SA Hoang, S Marukian, BR Blackman, ... JCI insight 1 (20), 2016 | 147 | 2016 |
Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro A Dash, MB Simmers, TG Deering, DJ Berry, RE Feaver, NE Hastings, ... American Journal of Physiology-Cell Physiology 304 (11), C1053-C1063, 2013 | 124 | 2013 |
Novel three‐dimensional organotypic liver bioreactor to directly visualize early events in metastatic progression C Yates, CR Shepard, G Papworth, A Dash, DB Stolz, S Tannenbaum, ... Advances in cancer research 97, 225-246, 2007 | 97 | 2007 |
Non-alcoholic fatty liver disease (NAFLD) models in drug discovery BK Cole, RE Feaver, BR Wamhoff, A Dash Expert opinion on drug discovery 13 (2), 193-205, 2018 | 90 | 2018 |
Drug-induced steatohepatitis A Dash, RA Figler, AJ Sanyal, BR Wamhoff Expert opinion on drug metabolism & toxicology 13 (2), 193-204, 2017 | 69 | 2017 |
Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system A Dash, RA Figler, BR Blackman, S Marukian, MS Collado, MJ Lawson, ... Toxicology In Vitro 39, 93-103, 2017 | 42 | 2017 |
Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytes Y Terelius, RA Figler, S Marukian, MS Collado, MJ Lawson, AJ Mackey, ... Chemico-biological interactions 255, 31-44, 2016 | 36 | 2016 |
Next‐generation DILI biomarkers: prioritization of biomarkers for qualification and best practices for biospecimen collection in drug development SE Roth, MI Avigan, D Bourdet, D Brott, R Church, A Dash, D Keller, ... Clinical Pharmacology & Therapeutics 107 (2), 333-346, 2020 | 34 | 2020 |
Phase 2 randomized clinical trial of astegolimab in patients with moderate to severe atopic dermatitis M Maurer, DS Cheung, W Theess, X Yang, M Dolton, A Guttman, DF Choy, ... Journal of Allergy and Clinical Immunology 150 (6), 1517-1524, 2022 | 32 | 2022 |
Consensus guidelines: best practices for detection, assessment and management of suspected acute drug-induced liver injury during clinical trials in adults with chronic viral … WR Treem, M Palmer, I Lonjon-Domanec, D Seekins, L Dimick-Santos, ... Drug Safety 44, 133-165, 2021 | 31 | 2021 |
Consensus guidelines: best practices for detection, assessment and management of suspected acute drug‐induced liver injury occurring during clinical trials in adults with … M Palmer, A Regev, K Lindor, MI Avigan, L Dimick‐Santos, W Treem, ... Alimentary Pharmacology & Therapeutics 51 (1), 90-109, 2020 | 30 | 2020 |
Fibroblast growth factor receptor 1/Klothoβ agonist BFKB8488A improves lipids and liver health markers in patients with diabetes or NAFLD: A phase 1b randomized trial C Wong, A Dash, J Fredrickson, N Lewin‐Koh, S Chen, K Yoshida, Y Liu, ... Hepatology 78 (3), 847-862, 2023 | 25 | 2023 |
Organotypic systems in drug metabolism and toxicity: challenges and opportunities A Dash, BR Blackman, BR Wamhoff Expert opinion on drug metabolism & toxicology 8 (8), 999-1014, 2012 | 23 | 2012 |
Systems biology for organotypic cell cultures S Grego, ER Dougherty, FJ Alexander, SS Auerbach, BR Berridge, ... Lawrence Livermore National Lab.(LLNL), Livermore, CA (United States); Los …, 2016 | 21 | 2016 |
Proteins Modified by the Lipid Peroxidation Aldehyde 9,12-Dioxo-10(E)-dodecenoic Acid in MCF7 Breast Cancer Cells PG Slade, MV Williams, V Brahmbhatt, A Dash, JS Wishnok, ... Chemical research in toxicology 23 (3), 557-567, 2010 | 19 | 2010 |
In vitro model for pathological or physiologic conditions BR Blackman, BR Wamhoff, A Dash, MB Simmers, RE Feaver US Patent 9,500,642, 2016 | 18 | 2016 |
Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes KA Chapman, MS Collado, RA Figler, SA Hoang, AJ Armstrong, W Cui, ... Molecular genetics and metabolism 117 (3), 355-362, 2016 | 18 | 2016 |