MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion G Sebastiani, A Po, E Miele, G Ventriglia, E Ceccarelli, M Bugliani, ... Acta Diabetologica 52, 523-530, 2015 | 153 | 2015 |
MicroRNAs as regulators of insulin signaling: research updates and potential therapeutic perspectives in type 2 diabetes L Nigi, GE Grieco, G Ventriglia, N Brusco, F Mancarella, C Formichi, ... International journal of molecular sciences 19 (12), 3705, 2018 | 110 | 2018 |
Circulating microRNAs and diabetes mellitus: a novel tool for disease prediction, diagnosis, and staging? G Sebastiani, L Nigi, GE Grieco, F Mancarella, G Ventriglia, F Dotta Journal of endocrinological investigation 40, 591-610, 2017 | 110 | 2017 |
Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression G Sebastiani, G Ventriglia, A Stabilini, C Socci, C Morsiani, A Laurenzi, ... Scientific reports 7 (1), 6897, 2017 | 69 | 2017 |
MicroRNAs: novel players in the dialogue between pancreatic islets and immune system in autoimmune diabetes G Ventriglia, L Nigi, G Sebastiani, F Dotta BioMed Research International 2015 (1), 749734, 2015 | 69 | 2015 |
Serum levels of miR-148a and miR-21-5p are increased in type 1 diabetic patients and correlated with markers of bone strength and metabolism GE Grieco, D Cataldo, E Ceccarelli, L Nigi, G Catalano, N Brusco, ... Non-coding RNA 4 (4), 37, 2018 | 56 | 2018 |
Intestinal Delivery of Proinsulin and IL-10 via Lactococcus lactis Combined With Low-Dose Anti-CD3 Restores Tolerance Outside the Window of Acute Type 1 … DP Cook, JPMCM Cunha, PJ Martens, G Sassi, F Mancarella, G Ventriglia, ... Frontiers in immunology 11, 1103, 2020 | 31 | 2020 |
MicroRNAs: markers of β-cell stress and autoimmunity F Dotta, G Ventriglia, IV Snowhite, A Pugliese Current Opinion in Endocrinology, Diabetes and Obesity 25 (4), 237-245, 2018 | 29 | 2018 |
miR-409-3p is reduced in plasma and islet immune infiltrates of NOD diabetic mice and is differentially expressed in people with type 1 diabetes G Ventriglia, F Mancarella, G Sebastiani, DP Cook, R Mallone, C Mathieu, ... Diabetologia 63, 124-136, 2020 | 28 | 2020 |
MicroRNA expression analysis of in vitro dedifferentiated human pancreatic islet cells reveals the activation of the pluripotency-related microRNA cluster miR-302s G Sebastiani, GE Grieco, N Brusco, G Ventriglia, C Formichi, L Marselli, ... International journal of molecular sciences 19 (4), 1170, 2018 | 17 | 2018 |
MicroRNA miR-124a, a negative regulator of insulin secretion, is hyperexpressed in human pancreatic islets of type 2 diabetic patients G Sebastiani, F Mancarella, G Ventriglia, L Nigi, M Valentini, GE Grieco, ... Rna & Disease 2, 2015 | 11 | 2015 |
Biomarkers for diabetes therapy C Gysemans, C Mathieu, F Dotta, G Sebastiani, G Ventriglia US Patent 12,139,761, 2024 | 2 | 2024 |
A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis–Based Antigen-Specific Immunotherapy in … G Sassi, G Licata, G Ventriglia, A Wouters, P Lemaitre, R Seurinck, A Mori, ... Diabetes 72 (10), 1470-1482, 2023 | 1 | 2023 |
Plasma levels of the miR-193b/365a cluster in combination with clinical parameters predict response to Lactococcus lactis-based antigen-specific combination therapy G Sassi, G Licata, G Ventriglia, D Ellis, N Van Damme, S Caluwaerts, ... Diabetologia 65 (SUPPL 1), S171-S171, 2022 | | 2022 |
Islet microRNA miR-183-5p is a regulator of beta cell apoptosis and dedifferentiation in NOD mouse pancreatic islet F Mancarella, G Ventriglia, L Nigi, GE Grieco, N Brusco, C Gysemans, ... Diabetologia 61, S35-S36, 2018 | | 2018 |
Characterisation of CXCL10 expression pattern in pancreatic islets of NOD mice and type 1 diabetic patients: a new role for alpha cells in T-lymphocytes recruitment L Nigi, F Mancarella, L Krogvold, L Marselli, G Sebastiani, G Ventriglia, ... Diabetologia 61, S201-S201, 2018 | | 2018 |
Circulating microRNA as biomarkers of autoimmune type 1 diabetes–Assessing the relevance of a target organ specific microRNA signature in type 1 diabetes G Ventriglia Università degli Studi di Siena, 2018 | | 2018 |
In-situ immunohistochemical detection of ZnT8</sub> 186-194<//sub> reactive CD8</SUP>+<//SUP> T cells in the pancreas of nPOD type 1 diabetic donors G Sebastiani, L Nigi, S Culina, G Afonso, G Ventriglia, S Buus, F Dotta, ... Diabetologia 60, S200-S201, 2017 | | 2017 |
MiR-409-3p, an IFN-γ targeting miRNA, is reduced in plasma of new-onset diabetic NOD mice and mirrors its in situ pancreatic islet expression G Ventriglia, F Mancarella, G Sebastiani, GE Grieco, L Nigi, DP Cook, ... Diabetologia 59, S224-S224, 2016 | | 2016 |
In type 2 diabetes, microRNA miR-184 is reduced in human pancreatic islets and targets CRTC1, a molecule that counteracts palmitate-induced apoptosis and functional damage G Sebastiani, GE Grieco, F Mancarella, G Ventriglia, L Nigi, L Marselli, ... Diabetologia 59, S217-S217, 2016 | | 2016 |