Targeting angiogenesis: structural characterization and biological properties of a de novo engineered VEGF mimicking peptide LD D'Andrea, G Iaccarino, R Fattorusso, D Sorriento, C Carannante, ... Proceedings of the National Academy of Sciences 102 (40), 14215-14220, 2005 | 314 | 2005 |
Critical DNA binding interactions of the insulator protein CTCF: a small number of zinc fingers mediate strong binding, and a single finger-DNA interaction controls binding at … M Renda, I Baglivo, B Burgess-Beusse, S Esposito, R Fattorusso, ... Journal of Biological Chemistry 282 (46), 33336-33345, 2007 | 189 | 2007 |
Efficient synthetic inhibitors of anthrax lethal factor M Forino, S Johnson, TY Wong, DV Rozanov, AY Savinov, W Li, ... Proceedings of the National Academy of Sciences 102 (27), 9499-9504, 2005 | 166 | 2005 |
The Arabidopsis SUPERMAN protein is able to specifically bind DNA through its single Cys 2 –His 2 zinc finger motif N Dathan, L Zaccaro, S Esposito, C Isernia, JG Omichinski, A Riccio, ... Nucleic acids research 30 (22), 4945-4951, 2002 | 105 | 2002 |
NMR-based techniques in the hit identification and optimisation processes M Pellecchia, B Becattini, KJ Crowell, R Fattorusso, M Forino, M Fragai, ... Expert opinion on therapeutic targets 8 (6), 597-611, 2004 | 100 | 2004 |
NMR structure of the human oncofoetal fibronectin ED-B domain, a specific marker for angiogenesis R Fattorusso, M Pellecchia, F Viti, P Neri, D Neri, K Wüthrich Structure 7 (4), 381-390, 1999 | 79 | 1999 |
Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein H S Galdiero, A Falanga, M Vitiello, L Raiola, R Fattorusso, H Browne, ... Journal of Biological Chemistry 283 (44), 29993-30009, 2008 | 75 | 2008 |
The prokaryotic zinc‐finger: structure, function and comparison with the eukaryotic counterpart G Malgieri, M Palmieri, L Russo, R Fattorusso, PV Pedone, C Isernia The FEBS journal 282 (23), 4480-4496, 2015 | 71 | 2015 |
Neuronal high-affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases G Campiani, C Fattorusso, M Angelis, B Catalanotti, S Butini, R Fattorusso, ... Current pharmaceutical design 9 (8), 599-625, 2003 | 68 | 2003 |
Design, structural and functional characterization of a Temporin-1b analog active against Gram-negative bacteria C Avitabile, F Netti, G Orefice, M Palmieri, N Nocerino, G Malgieri, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (6), 3767-3775, 2013 | 66 | 2013 |
A new ligand for immunoglobulin G subdomains by screening of a synthetic peptide library A Verdoliva, D Marasco, A De Capua, A Saporito, P Bellofiore, V Manfredi, ... ChemBioChem 6 (7), 1242-1253, 2005 | 66 | 2005 |
The structural role of the zinc ion can be dispensable in prokaryotic zinc-finger domains I Baglivo, L Russo, S Esposito, G Malgieri, M Renda, A Salluzzo, ... Proceedings of the National Academy of Sciences 106 (17), 6933-6938, 2009 | 62 | 2009 |
The Inorganic Perspective of Nerve Growth Factor: Interactions of Cu2+ and Zn2+ with the N‐Terminus Fragment of Nerve Growth Factor Encompassing the … A Travaglia, G Arena, R Fattorusso, C Isernia, D La Mendola, G Malgieri, ... Chemistry–A European Journal 17 (13), 3726-3738, 2011 | 61 | 2011 |
The prokaryotic Cys2His2 zinc-finger adopts a novel fold as revealed by the NMR structure of Agrobacterium tumefaciens Ros DNA-binding domain G Malgieri, L Russo, S Esposito, I Baglivo, L Zaccaro, EM Pedone, ... Proceedings of the National Academy of Sciences 104 (44), 17341-17346, 2007 | 57 | 2007 |
NMR Structure of the Single QALGGH Zinc Finger Domain from the Arabidopsis thaliana SUPERMAN Protein C Isernia, E Bucci, M Leone, L Zaccaro, P Di Lello, G Digilio, S Esposito, ... Chembiochem 4 (2‐3), 171-180, 2003 | 56 | 2003 |
Alpha-and beta-cyclodextrin inclusion complexes with 5-fluorouracil: Characterization and cytotoxic activity evaluation C Di Donato, M Lavorgna, R Fattorusso, C Isernia, M Isidori, G Malgieri, ... Molecules 21 (12), 1644, 2016 | 54 | 2016 |
Structural determinants of the unusual helix stability of a de novo engineered vascular endothelial growth factor (VEGF) mimicking peptide (432 views) D Diana, B Ziaco, G Colombo, G Scarabelli, A Romanelli, C Fedone, ... Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic) 14 (14), 4164-4166, 2008 | 54 | 2008 |
Characterization of a designed vascular endothelial growth factor receptor antagonist helical peptide with antiangiogenic activity in vivo A Basile, A Del Gatto, D Diana, R Di Stasi, A Falco, M Festa, A Rosati, ... Journal of medicinal chemistry 54 (5), 1391-1400, 2011 | 53 | 2011 |
Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways F Bellia, V Lanza, S García-Viñuales, IMM Ahmed, A Pietropaolo, ... Chemical science 10 (9), 2732-2742, 2019 | 51 | 2019 |
Discovery of a novel class of reversible non-peptide caspase inhibitors via a structure-based approach R Fattorusso, D Jung, KJ Crowell, M Forino, M Pellecchia Journal of medicinal chemistry 48 (5), 1649-1656, 2005 | 51 | 2005 |