Design and characterization of an APC-specific serpin for the treatment of hemophilia SGI Polderdijk, TE Adams, L Ivanciu, RM Camire, TP Baglin, ... Blood, The Journal of the American Society of Hematology 129 (1), 105-113, 2017 | 153 | 2017 |
Targeting activated protein C to treat hemophilia SGI Polderdijk, TP Baglin, JA Huntington Current opinion in hematology 24 (5), 446-452, 2017 | 55 | 2017 |
A Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesis K Knezevic, T Bee, NK Wilson, ME Janes, S Kinston, S Polderdijk, ... Molecular and cellular biology, 2011 | 44 | 2011 |
Ixodes ricinus Salivary Serpin Iripin-8 Inhibits the Intrinsic Pathway of Coagulation and Complement J Kotál, SGI Polderdijk, H Langhansová, M Ederová, LA Martins, ... International Journal of Molecular Sciences 22 (17), 9480, 2021 | 23 | 2021 |
Characterization of bispecific and mispaired IgGs by native charge-variant mass spectrometry W Phung, G Han, SGI Polderdijk, M Dillon, W Shatz, P Liu, B Wei, ... International Journal of Mass Spectrometry 446, 116229, 2019 | 17 | 2019 |
Identification of serpins specific for activated protein C using a lysate-based screening assay SGI Polderdijk, JA Huntington Scientific Reports 8 (1), 8793, 2018 | 17 | 2018 |
Parallel imaging of coagulation pathway proteases activated protein C, thrombin, and factor Xa in human plasma S Modrzycka, S Kołt, SGI Polderdijk, TE Adams, S Potoczek, ... Chemical Science 13 (23), 6813-6829, 2022 | 6 | 2022 |
Data on charge separation of bispecific and mispaired IgGs using native charge-variant mass spectrometry W Phung, G Han, SGI Polderdijk, M Dillon, W Shatz, P Liu, B Wei, ... Data in Brief 30, 105435, 2020 | 6 | 2020 |
Modified serpins for the treatment of bleeding disorders JA Huntington, S Polderdijk, T Baglin | 2 | 2015 |
Plasma membrane damage limits cytoplasmic delivery by conventional cell penetrating peptides SGI Polderdijk, JF Limzerwala, C Spiess PloS one 19 (9), e0305848, 2024 | | 2024 |
Modified serpins for the treatment of bleeding disorders JA Huntington, S Polderdijk, T Baglin US Patent 10,351,619, 2019 | | 2019 |
Modifikovani serpini za lečenje poremećaja krvarenja JA Huntington, S Polderdijk, T Baglin | | 2019 |
MODIFIED SERPINES TO TREAT Bleeding disorders JA Huntington, S Polderdijk, T Baglin | | 2018 |
Modifikuoti serpinai, skirti kraujavimo sutrikimų gydymui JA HUNTINGTON, S POLDERDIJK, T Baglin | | 2018 |
Pre-clinical studies demonstrate the efficacy and safety of SerpinPC, a specific inhibitor of the protein C pathway J Huntington, S Polderdijk, T Baglin HAEMOPHILIA 24, 79-79, 2018 | | 2018 |
The extended reactive centre loop of protein C inhibitor balances its pro-and anti-coagulant functions SG Polderdijk, JA Huntington JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11, 184-184, 2013 | | 2013 |
Patent 2933508 Summary JA HUNTINGTON, S POLDERDIJK, T BAGLIN | | |