An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease Y Peng, SL Felce, D Dong, F Penkava, AJ Mentzer, X Yao, G Liu, Z Yin, ... Nature immunology 23 (1), 50-61, 2022 | 143 | 2022 |
How does vaccinia virus interfere with interferon? GL Smith, C Talbot-Cooper, Y Lu Advances in virus research 100, 355-378, 2018 | 69 | 2018 |
Vaccinia virus protein C6 inhibits type I IFN signalling in the nucleus and binds to the transactivation domain of STAT2 JH Stuart, RP Sumner, Y Lu, JS Snowden, GL Smith PLoS pathogens 12 (12), e1005955, 2016 | 68 | 2016 |
Histone deacetylase 4 promotes type I interferon signaling, restricts DNA viruses, and is degraded via vaccinia virus protein C6 Y Lu, JH Stuart, C Talbot-Cooper, S Agrawal-Singh, B Huntly, AI Smid, ... Proceedings of the National Academy of Sciences 116 (24), 11997-12006, 2019 | 67 | 2019 |
Quantitative temporal proteomic analysis of vaccinia virus infection reveals regulation of histone deacetylases by an interferon antagonist L Soday, Y Lu, JD Albarnaz, CTR Davies, R Antrobus, GL Smith, ... Cell reports 27 (6), 1920-1933. e7, 2019 | 62 | 2019 |
The replication defect of ICP0-null mutant herpes simplex virus 1 can be largely complemented by the combined activities of human cytomegalovirus proteins IE1 and pp71 RD Everett, AJ Bell, Y Lu, A Orr Journal of virology 87 (2), 978-990, 2013 | 36 | 2013 |
An overview of current knowledge of deadly CoVs and their interface with innate immunity Y Zhang, S Gargan, Y Lu, NJ Stevenson Viruses 13 (4), 560, 2021 | 20 | 2021 |
TRIM5α restricts poxviruses and is antagonized by CypA and the viral protein C6 Y Zhao, Y Lu, S Richardson, M Sreekumar, JD Albarnaz, GL Smith Nature 620 (7975), 873-880, 2023 | 16 | 2023 |
Stimulation of the replication of ICP0-null mutant herpes simplex virus 1 and pp71-deficient human cytomegalovirus by epstein-barr virus tegument protein BNRF1 Y Lu, A Orr, RD Everett Journal of Virology 90 (21), 9664-9673, 2016 | 14 | 2016 |
Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins Y Lu, HA Michel, PH Wang, GL Smith Frontiers in Microbiology 13, 1027015, 2022 | 13 | 2022 |
Analysis of the functional interchange between the IE1 and pp71 proteins of human cytomegalovirus and ICP0 of herpes simplex virus 1 Y Lu, RD Everett Journal of Virology 89 (6), 3062-3075, 2015 | 12 | 2015 |
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity H Stewart, Y Lu, S O’Keefe, A Valpadashi, LD Cruz-Zaragoza, HA Michel, ... Iscience 26 (11), 2023 | 10 | 2023 |
DDX50 is a viral restriction factor that enhances IRF3 activation MA Pallett, Y Lu, GL Smith Viruses 14 (2), 316, 2022 | 10 | 2022 |
Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination Z Yin, JL Chen, Y Lu, B Wang, L Godfrey, AJ Mentzer, X Yao, G Liu, ... Cell Reports 42 (5), 2023 | 2 | 2023 |
HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus Y Lu, Y Zhao, C Gao, S Suresh, J Men, A Sawyers, GL Smith Cell Reports 43 (3), 2024 | 1 | 2024 |
Filamin B restricts vaccinia virus spread and is targeted by vaccinia virus protein C4 I Georgana, SR Scutts, C Gao, Y Lu, AA Torres, H Ren, E Emmott, J Men, ... Journal of Virology 98 (3), e01485-23, 2024 | | 2024 |
DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation. Viruses 2022, 14, 316 MA Pallett, Y Lu, GL Smith s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2022 | | 2022 |
Inhibition of IFN-gamma signalling by vaccinia virus protein C6: a multi-functional interferon antagonist C Talbot-Cooper, Y Lu, J Stewart, G Smith Access Microbiology 1 (1A), 795, 2019 | | 2019 |
Functional comparison of regulatory proteins expressed by different Herpes viruses Y Lu University of Glasgow, 2015 | | 2015 |