Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt G Kulik, A Klippel, MJ Weber Molecular and cellular biology 17 (3), 1595-1606, 1997 | 1347 | 1997 |
Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids IM Berquin, Y Min, R Wu, J Wu, D Perry, JM Cline, MJ Thomas, ... The Journal of clinical investigation 117 (7), 1866-1875, 2007 | 366 | 2007 |
Akt-dependent and-independent survival signaling pathways utilized by insulin-like growth factor I G Kulik, MJ Weber Molecular and cellular biology, 1998 | 306 | 1998 |
Behavioral stress accelerates prostate cancer development in mice S Hassan, Y Karpova, D Baiz, D Yancey, A Pullikuth, A Flores, T Register, ... The Journal of clinical investigation 123 (2), 2013 | 276 | 2013 |
Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation KSR Sastry, Y Karpova, S Prokopovich, AJ Smith, B Essau, A Gersappe, ... Journal of Biological Chemistry 282 (19), 14094-14100, 2007 | 255 | 2007 |
Antiapoptotic signaling in LNCaP prostate cancer cells: a survival signaling pathway independent of phosphatidylinositol 3′-kinase and Akt/protein kinase B JP Carson, G Kulik, MJ Weber Cancer research 59 (7), 1449-1453, 1999 | 200 | 1999 |
Src phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites: requirement for transformation by src JE Peterson, G Kulik, T Jelinek, CWM Reuter, JA Shannon, MJ Weber Journal of Biological Chemistry 271 (49), 31562-31571, 1996 | 120 | 1996 |
Dimeric DNA aptamer complexes for high-capacity–targeted drug delivery using pH-sensitive covalent linkages O Boyacioglu, CH Stuart, G Kulik, WH Gmeiner Molecular Therapy-Nucleic Acids 2, 2013 | 97 | 2013 |
Recent syntheses of PI3K/Akt/mTOR signaling pathway inhibitors ME Welker, G Kulik Bioorganic & medicinal chemistry 21 (14), 4063-4091, 2013 | 84 | 2013 |
Epidermal growth factor protects prostate cancer cells from apoptosis by inducing BAD phosphorylation via redundant signaling pathways KSR Sastry, Y Karpova, G Kulik Journal of Biological Chemistry 281 (37), 27367-27377, 2006 | 70 | 2006 |
Tumor necrosis factor α induces BID cleavage and bypasses antiapoptotic signals in prostate cancer LNCaP cells G Kulik, JP Carson, T Vomastek, K Overman, BD Gooch, S Srinivasula, ... Cancer research 61 (6), 2713-2719, 2001 | 64 | 2001 |
Synthesis and characterization of a novel prostate cancer-targeted phosphatidylinositol-3-kinase inhibitor prodrug D Baiz, TA Pinder, S Hassan, Y Karpova, F Salsbury, ME Welker, G Kulik Journal of medicinal chemistry 55 (18), 8038-8046, 2012 | 59 | 2012 |
Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cells KSR Sastry, MA Al-Muftah, P Li, MK Al-Kowari, E Wang, ... Cell Death & Differentiation 21 (12), 1936-1949, 2014 | 56 | 2014 |
Smac is required for cytochrome c-induced apoptosis in prostate cancer LNCaP cells JP Carson, M Behnam, JN Sutton, C Du, X Wang, DF Hunt, MJ Weber, ... Cancer Research 62 (1), 18-23, 2002 | 56 | 2002 |
Expression of the Bcl-2 protein BAD promotes prostate cancer growth AJ Smith, Y Karpova, R D'Agostino Jr, M Willingham, G Kulik PloS one 4 (7), e6224, 2009 | 53 | 2009 |
Diverse antiapoptotic signaling pathways activated by vasoactive intestinal polypeptide, epidermal growth factor, and phosphatidylinositol 3-kinase in prostate cancer cells … KSR Sastry, AJ Smith, Y Karpova, SR Datta, G Kulik Journal of Biological Chemistry 281 (30), 20891-20901, 2006 | 52 | 2006 |
Systems modeling of anti-apoptotic pathways in prostate cancer: psychological stress triggers a synergism pattern switch in drug combination therapy X Sun, J Bao, KC Nelson, KC Li, G Kulik, X Zhou PLoS computational biology 9 (12), e1003358, 2013 | 42 | 2013 |
Combination of the PI3K inhibitor ZSTK474 with a PSMA-targeted immunotoxin accelerates apoptosis and regression of prostate cancer D Baiz, S Hassan, YA Choi, A Flores, Y Karpova, D Yancey, A Pullikuth, ... Neoplasia 15 (10), 1172-IN32, 2013 | 38 | 2013 |
ADRB2-Targeting therapies for prostate cancer G Kulik Cancers 11 (3), 358, 2019 | 36 | 2019 |
Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation Q Zhang, M Wan, J Shi, DA Horita, LD Miller, TE Kute, SJ Kridel, G Kulik, ... Journal of molecular cell biology 8 (3), 232-243, 2016 | 32 | 2016 |