| The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation PJ Van der Watt, CP Maske, DT Hendricks, MI Parker, L Denny, ... International journal of cancer 124 (8), 1829-1840, 2009 | 361 | 2009 |
| Targeting the nuclear import receptor Kpnβ1 as an anticancer therapeutic PJ van der Watt, A Chi, T Stelma, C Stowell, E Strydom, S Carden, ... Molecular Cancer Therapeutics 15 (4), 560-573, 2016 | 78 | 2016 |
| Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activity PJ van der Watt, E Ngarande, VD Leaner PLoS One 6 (11), e27723, 2011 | 64 | 2011 |
| Targeting nuclear transporters in cancer: diagnostic, prognostic and therapeutic potential T Stelma, A Chi, PJ Van Der Watt, A Verrico, P Lavia, VD Leaner IUBMB life 68 (4), 268-280, 2016 | 60 | 2016 |
| The nuclear exporter, Crm1, is regulated by NFY and Sp1 in cancer cells and repressed by p53 in response to DNA damage PJ van der Watt, VD Leaner Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1809 (7), 316-326, 2011 | 60 | 2011 |
| Photolon™, a chlorin e6 derivative, triggers ROS production and light-dependent cell death via necrosis L Copley, P van der Watt, KW Wirtz, MI Parker, VD Leaner The International Journal of Biochemistry & Cell Biology 40 (2), 227-235, 2008 | 59 | 2008 |
| Elevated expression of the nuclear export protein, Crm1 (exportin 1), associates with human oesophageal squamous cell carcinoma PJ Van der Watt, W Zemanay, D Govender, DT Hendricks, MI Parker, ... Oncology Reports 32 (2), 730-738, 2014 | 49 | 2014 |
| Inhibition of the nuclear transporter, Kpnβ1, results in prolonged mitotic arrest and activation of the intrinsic apoptotic pathway in cervical cancer cells L Angus, PJ van der Watt, VD Leaner Carcinogenesis 35 (5), 1121-1131, 2014 | 43 | 2014 |
| The nuclear import receptor Kpnβ1 and its potential as an anticancer therapeutic target PJ van der Watt, CL Stowell, VD Leaner Critical Reviews™ in Eukaryotic Gene Expression 23 (1), 2013 | 38 | 2013 |
| The tumour suppressing role of the circadian clock K Davis, LC Roden, VD Leaner, PJ van der Watt IUBMB life 71 (7), 771-780, 2019 | 36 | 2019 |
| Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression MF Maritz, PJ van der Watt, N Holderness, MJ Birrer, VD Leaner Walter de Gruyter 392 (5), 439-448, 2011 | 29 | 2011 |
| Nuclear transport proteins are secreted by cancer cells and identified as potential novel cancer biomarkers PJ van der Watt, MO Okpara, A Wishart, MI Parker, NC Soares, ... International Journal of Cancer 150 (2), 347-361, 2022 | 15 | 2022 |
| Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer RA Chi, P van der Watt, W Wei, MJ Birrer, VD Leaner BMC cancer 21, 1-16, 2021 | 15 | 2021 |
| Circadian oscillations persist in cervical and esophageal cancer cells displaying decreased expression of tumor-suppressing circadian clock genes PJ van der Watt, LC Roden, KT Davis, MI Parker, VD Leaner Molecular Cancer Research 18 (9), 1340-1353, 2020 | 15 | 2020 |
| Deregulated LAP2α expression in cervical cancer associates with aberrant E2F and p53 activities MC Ward, PJ van der Watt, G Tzoneva, VD Leaner IUBMB life 63 (11), 1018-1026, 2011 | 12 | 2011 |
| A tight balance of Karyopherin β1 expression is required in cervical cancer cells S Carden, P van der Watt, A Chi, A Ajayi-Smith, K Hadley, VD Leaner BMC cancer 18, 1-15, 2018 | 11 | 2018 |
| Interfering with nuclear transport as a means of interrupting transcription factor activity in cancer AF Ajayi-Smith, PJ van der Watt, VD Leaner Critical Reviews™ in Eukaryotic Gene Expression 29 (5), 2019 | 9 | 2019 |
| Novel small molecule inhibitor of Kpnβ1 induces cell cycle arrest and apoptosis in cancer cells A Ajayi-Smith, P van der Watt, N Mkwanazi, S Carden, JO Trent, ... Experimental Cell Research 404 (2), 112637, 2021 | 6 | 2021 |
| High-affinity binding of southern African HIV type 1 subtype C envelope protein, gp120, to the CCR5 coreceptor BJ Fromme, M Coetsee, P Van Der Watt, MC Chan, KM Sperling, AA Katz, ... AIDS research and human retroviruses 24 (12), 1527-1536, 2008 | 6 | 2008 |
| E-box binding transcription factors in cancer Y Pan, PJ van der Watt, SA Kay Frontiers in Oncology 13, 1223208, 2023 | 3 | 2023 |
