Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention M Inouye, G Abraham, CP Nelson, AM Wood, MJ Sweeting, F Dudbridge, ... Journal of the American College of Cardiology 72 (16), 1883-1893, 2018 | 673 | 2018 |
Towards clinical utility of polygenic risk scores SA Lambert, G Abraham, M Inouye Human molecular genetics 28 (R2), R133-R142, 2019 | 474 | 2019 |
The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation SA Lambert, L Gil, S Jupp, SC Ritchie, Y Xu, A Buniello, A McMahon, ... Nature Genetics, 1-6, 2021 | 399 | 2021 |
Genomic prediction of coronary heart disease G Abraham, AS Havulinna, OG Bhalala, SG Byars, AM De Livera, ... European heart journal 37 (43), 3267-3278, 2016 | 352 | 2016 |
FlashPCA2: principal component analysis of Biobank-scale genotype datasets G Abraham, Y Qiu, M Inouye Bioinformatics 33 (17), 2776-2778, 2017 | 341 | 2017 |
Fast Principal Component Analysis of Large-Scale Genome-Wide Data G Abraham, M Inouye PloS one 9 (4), e93766, 2014 | 334 | 2014 |
The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection SC Ritchie, P Würtz, AP Nath, G Abraham, AS Havulinna, LG Fearnley, ... Cell Systems 1 (4), 293-301, 2015 | 211 | 2015 |
Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke G Abraham, R Malik, E Yonova-Doing, A Salim, T Wang, J Danesh, ... Nature Communications 10 (1), 1-10, 2019 | 168 | 2019 |
Short-term forecasting of emergency inpatient flow G Abraham, GB Byrnes, CA Bain IEEE Transactions on Information Technology in Biomedicine 13 (3), 380-388, 2009 | 148 | 2009 |
Genomic risk prediction of complex human disease and its clinical application G Abraham, M Inouye Current Opinion in Genetics & Development 33, 10-16, 2015 | 142 | 2015 |
Performance and Robustness of Penalized and Unpenalized Methods for Genetic Prediction of Complex Human Disease G Abraham, A Kowalczyk, J Zobel, M Inouye Genetic Epidemiology 37 (2), 184-195, 2013 | 137 | 2013 |
Accurate and robust genomic prediction of celiac disease using statistical learning G Abraham, JA Tye-Din, OG Bhalala, A Kowalczyk, J Zobel, M Inouye PLoS Genetics 10 (2), e1004137, 2014 | 125 | 2014 |
Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses L Sun, L Pennells, S Kaptoge, CP Nelson, SC Ritchie, G Abraham, ... PLoS medicine 18 (1), e1003498, 2021 | 117 | 2021 |
Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context G Abraham, A Kowalczyk, S Loi, I Haviv, J Zobel BMC bioinformatics 11 (1), 277, 2010 | 99 | 2010 |
Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy SG Byars, QQ Huang, LA Gray, A Bakshi, S Ripatti, G Abraham, ... PLOS Genetics 13 (6), e1006328, 2017 | 69 | 2017 |
A Scalable Permutation Approach Reveals Replication and Preservation Patterns of Network Modules in Large Datasets SC Ritchie, S Watts, LG Fearnley, KE Holt, G Abraham, M Inouye Cell Systems 3 (1), 71-82, 2016 | 64 | 2016 |
Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases SC Ritchie, SA Lambert, M Arnold, SM Teo, S Lim, P Scepanovic, ... Nature Metabolism, 1-8, 2021 | 55 | 2021 |
An interaction map of circulating metabolites, immune gene networks, and their genetic regulation AP Nath, SC Ritchie, SG Byars, LG Fearnley, AS Havulinna, A Joensuu, ... Genome Biology 18 (1), 146, 2017 | 46 | 2017 |
SparSNP: Fast and memory-efficient analysis of all SNPs for phenotype prediction G Abraham, A Kowalczyk, J Zobel, M Inouye BMC bioinformatics 13 (1), 88, 2012 | 44 | 2012 |
Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy AP Nath, SC Ritchie, NF Grinberg, HHF Tang, QQ Huang, SM Teo, ... The American Journal of Human Genetics 105 (6), 1076-1090, 2019 | 31 | 2019 |