Highly efficient therapeutic gene editing of human hematopoietic stem cells Y Wu, J Zeng, BP Roscoe, P Liu, Q Yao, CR Lazzarotto, K Clement, ... Nature medicine 25 (5), 776-783, 2019 | 439 | 2019 |
Therapeutic base editing of human hematopoietic stem cells J Zeng, Y Wu, C Ren, J Bonanno, AH Shen, D Shea, JM Gehrke, ... Nature Medicine 26 (4), 535-541, 2020 | 235 | 2020 |
Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain C Ren, K Morohashi, AN Plotnikov, J Jakoncic, SG Smith, J Li, L Zeng, ... Chemistry & biology 22 (2), 161-168, 2015 | 136 | 2015 |
Distinct roles of Brd2 and Brd4 in potentiating the transcriptional program for Th17 cell differentiation KL Cheung, F Zhang, A Jaganathan, R Sharma, Q Zhang, T Konuma, ... Molecular cell 65 (6), 1068-1080. e5, 2017 | 130 | 2017 |
Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis F Sher, M Hossain, D Seruggia, VAC Schoonenberg, Q Yao, P Cifani, ... Nature Genetics 51, 1149–1159, 2019 | 95 | 2019 |
CRISPRminer is a knowledge base for exploring CRISPR-Cas systems in microbe and phage interactions F Zhang, S Zhao, C Ren, Y Zhu, H Zhou, Y Lai, F Zhou, Y Jia, K Zheng, ... Communications Biology 1 (1), 1-5, 2018 | 80 | 2018 |
Structure-guided discovery of selective antagonists for the chromodomain of polycomb repressive protein CBX7 C Ren, SG Smith, K Yap, SD Li, J Li, M Mezei, Y Rodriguez, A Vincek, ... ACS medicinal chemistry letters 7 (6), 601-605, 2016 | 73 | 2016 |
Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth C Ren, G Zhang, F Han, S Fu, Y Cao, F Zhang, Q Zhang, J Meslamani, ... Proceedings of the National Academy of Sciences 115 (31), 7949-7954, 2018 | 57 | 2018 |
Extraction and identification of collagen-derived peptides with hematopoietic activity from Colla Corii Asini H Wu, C Ren, F Yang, Y Qin, Y Zhang, J Liu Journal of ethnopharmacology 182, 129-136, 2016 | 55 | 2016 |
MicroRNA-137 represses Klf4 and Tbx3 during differentiation of mouse embryonic stem cells K Jiang, C Ren, VD Nair Stem cell research 11 (3), 1299-1313, 2013 | 55 | 2013 |
ZNF410 represses fetal globin by singular control of CHD4 DS Vinjamur, Q Yao, MA Cole, C McGuckin, C Ren, J Zeng, M Hossain, ... Nature Genetics, 1-10, 2021 | 50 | 2021 |
Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program Y Hu, AM Stilp, CP McHugh, S Rao, D Jai, X Zheng, J Lane, ... The American Journal of Human Genetics, 2021 | 49 | 2021 |
Structural mechanism of the oxygenase JMJD6 recognition by the extraterminal (ET) domain of BRD4 T Konuma, D Yu, C Zhao, Y Ju, R Sharma, C Ren, Q Zhang, MM Zhou, ... Scientific reports 7 (1), 1-10, 2017 | 38 | 2017 |
Dissecting ELANE neutropenia pathogenicity by human HSC gene editing S Rao, Y Yao, JS de Brito, Q Yao, AH Shen, RE Watkinson, AL Kennedy, ... Cell Stem Cell, 2021 | 33 | 2021 |
A network medicine approach to build a comprehensive atlas for the prognosis of human cancer F Zhang, C Ren, KK Lau, Z Zheng, G Lu, Z Yi, Y Zhao, F Su, S Zhang, ... Briefings in bioinformatics 17 (6), 1044-1059, 2016 | 30 | 2016 |
Fli-1 Activation through Targeted Promoter Activity Regulation Using a Novel 3’, 5’-diprenylated Chalcone Inhibits Growth and Metastasis of Prostate Cancer Cells Y Ma, B Xu, J Yu, L Huang, X Zeng, X Shen, C Ren, Y Ben-David, H Luo International Journal of Molecular Sciences 21 (6), 2216, 2020 | 19 | 2020 |
PHISDetector: A tool to detect diverse in silico phage–host interaction signals for virome studies F Zhou, R Gan, F Zhang, C Ren, L Yu, Y Si, Z Huang Genomics, Proteomics & Bioinformatics, 2022 | 18 | 2022 |
PHISDetector: a web tool to detect diverse in silico phage-host interaction signals F Zhang, F Zhou, R Gan, C Ren, Y Jia, L Yu, Z Huang bioRxiv, 661074, 2019 | 18 | 2019 |
DBSCAN-SWA: An Integrated Tool for Rapid Prophage Detection and Annotation R Gan, FX Zhou, Y Si, H Yang, C Chen, C Ren, J Wu, F Zhang Frontiers in Genetics 13, 2022 | 16 | 2022 |
Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin N Liu, T Konuma, R Sharma, D Wang, N Zhao, L Cao, Y Ju, D Liu, ... Molecular Cell, 2023 | 14 | 2023 |