The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo G Crispatzu, R Rehimi, T Pachano, T Bleckwehl, S Cruz-Molina, C Xiao, ... Nature communications 12 (1), 4344, 2021 | 66 | 2021 |
Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness T Pachano, V Sánchez-Gaya, T Ealo, M Mariner-Faulí, T Bleckwehl, ... Nature genetics 53 (7), 1036-1049, 2021 | 65 | 2021 |
Epigenetics regulates transcription and pathogenesis in the parasite Trichomonas vaginalis T Pachano, YR Nievas, A Lizarraga, PJ Johnson, PH Strobl‐Mazzulla, ... Cellular microbiology 19 (6), e12716, 2017 | 27 | 2017 |
Enhancer-gene specificity in development and disease T Pachano, E Haro, A Rada-Iglesias Development 149 (11), dev186536, 2022 | 24 | 2022 |
Polycomb proteins as organizers of 3D genome architecture in embryonic stem cells T Pachano, G Crispatzu, A Rada-Iglesias Briefings in Functional Genomics 18 (6), 358-366, 2019 | 24 | 2019 |
Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes T Pachano, V Sánchez-Gaya, M Mariner-Faulí, T Ealo, HG Asenjo, ... biorxiv, 2020.08. 05.237768, 2020 | 8 | 2020 |
Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells HG Asenjo, M Alcazar-Fabra, M Espinosa-Martínez, L Lopez-Onieva, ... Nature Communications 14 (1), 180, 2023 | 3 | 2023 |
Protocol to study sufficiency of cis-regulatory elements in mouse embryonic stem cells using a CRISPR-mediated knockin approach T Pachano, A Rada-Iglesias STAR protocols 3 (3), 101492, 2022 | | 2022 |
Polycomb repression during S/G2 phases restrain initiation of cell differentiation to the G1 phase of the cell cycle HG Asenjo, M Alcazar-Fabra, M Espinosa, L Lopez-Onieva, A Gallardo, ... bioRxiv, 2022.07. 26.501502, 2022 | | 2022 |
Orphan CpG islands dictate the compatibility between poised enhancers and their target genes T Pachano Universität zu Köln, 2022 | | 2022 |
ISID Research Grant Report N de Miguel, T Pachano | | |