Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases H Zhang, X Ji, P Li, C Liu, J Lou, Z Wang, W Wen, Y Xiao, M Zhang, X Zhu Science China Life Sciences 63, 953-985, 2020 | 225 | 2020 |
BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma JT Li, M Yin, D Wang, J Wang, MZ Lei, Y Zhang, Y Liu, L Zhang, SW Zou, ... Nature cell biology 22 (2), 167-174, 2020 | 150 | 2020 |
Myosin VI undergoes cargo-mediated dimerization C Yu, W Feng, Z Wei, Y Miyanoiri, W Wen, Y Zhao, M Zhang Cell 138 (3), 537-548, 2009 | 147 | 2009 |
LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways J Zhu, W Wen, Z Zheng, Y Shang, Z Wei, Z Xiao, Z Pan, Q Du, W Wang, ... Molecular cell 43 (3), 418-431, 2011 | 131 | 2011 |
Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho‐protein‐binding modules J Zhu, Y Shang, C Xia, W Wang, W Wen, M Zhang The EMBO journal 30 (24), 4986-4997, 2011 | 126 | 2011 |
Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor R Wang, Z Wei, H Jin, H Wu, C Yu, W Wen, LN Chan, Z Wen, M Zhang Molecular cell 33 (6), 692-703, 2009 | 115 | 2009 |
Structure of the split PH domain and distinct lipid‐binding properties of the PH–PDZ supramodule of α‐syntrophin J Yan, W Wen, W Xu, J Long, ME Adams, SC Froehner, M Zhang The EMBO journal 24 (23), 3985-3995, 2005 | 89 | 2005 |
Par complex cluster formation mediated by phase separation Z Liu, Y Yang, A Gu, J Xu, Y Mao, H Lu, W Hu, QY Lei, Z Li, M Zhang, ... Nature communications 11 (1), 2266, 2020 | 87 | 2020 |
The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye W Liu, W Wen, Z Wei, J Yu, F Ye, CH Liu, RC Hardie, M Zhang Cell 145 (7), 1088-1101, 2011 | 80 | 2011 |
Cdc42‐dependent formation of the ZO‐1/MRCKβ complex at the leading edge controls cell migration L Huo, W Wen, R Wang, C Kam, J Xia, W Feng, M Zhang The EMBO journal 30 (4), 665-678, 2011 | 75 | 2011 |
Allosteric auto‐inhibition and activation of the Nedd4 family E3 ligase Itch K Zhu, Z Shan, X Chen, Y Cai, L Cui, W Yao, Z Wang, P Shi, C Tian, J Lou, ... EMBO reports 18 (9), 1618-1630, 2017 | 66 | 2017 |
Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division Z Shan, Y Tu, Y Yang, Z Liu, M Zeng, H Xu, J Long, M Zhang, Y Cai, ... Nature communications 9 (1), 737, 2018 | 62 | 2018 |
Structure basis and unconventional lipid membrane binding properties of the PH-C1 tandem of rho kinases W Wen, W Liu, J Yan, M Zhang Journal of biological chemistry 283 (38), 26263-26273, 2008 | 61 | 2008 |
Serine 88 phosphorylation of the 8-kDa dynein light chain 1 is a molecular switch for its dimerization status and functions C Song, W Wen, SK Rayala, M Chen, J Ma, M Zhang, R Kumar Journal of biological chemistry 283 (7), 4004-4013, 2008 | 61 | 2008 |
Structural characterization of the split pleckstrin homology domain in phospholipase C-γ1 and its interaction with TRPC3 W Wen, J Yan, M Zhang Journal of biological chemistry 281 (17), 12060-12068, 2006 | 61 | 2006 |
Protein complex assemblies in epithelial cell polarity and asymmetric cell division W Wen, M Zhang Journal of molecular biology 430 (19), 3504-3520, 2018 | 53 | 2018 |
Identification of the yeast R-SNARE Nyv1p as a novel longin domain-containing protein W Wen, L Chen, H Wu, X Sun, M Zhang, DK Banfield Molecular biology of the cell 17 (10), 4282-4299, 2006 | 53 | 2006 |
A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases Z Wang, Z Liu, X Chen, J Li, W Yao, S Huang, A Gu, QY Lei, Y Mao, ... Nature communications 10 (1), 3162, 2019 | 48 | 2019 |
Lipid-Induced conformational switch controls fusion activity of longin domain SNARE Ykt6 W Wen, J Yu, L Pan, Z Wei, J Weng, W Wang, YS Ong, THT Tran, W Hong, ... Molecular cell 37 (3), 383-395, 2010 | 48 | 2010 |
Phosphorylation of DCC by ERK2 is facilitated by direct docking of the receptor P1 domain to the kinase W Ma, Y Shang, Z Wei, W Wen, W Wang, M Zhang Structure 18 (11), 1502-1511, 2010 | 43 | 2010 |