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Luke Jostins
Luke Jostins
University of Oxford
在 sanger.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
A map of human genome variation from population scale sequencing
1000 Genomes Project Consortium
Nature 467 (7319), 1061, 2010
83632010
An integrated map of genetic variation from 1,092 human genomes
1000 Genomes Project Consortium
Nature 491 (7422), 56, 2012
79262012
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ...
Nature 491 (7422), 119-124, 2012
4859*2012
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ...
Nature genetics 42 (12), 1118-1125, 2010
29522010
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
JZ Liu, S Van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, ...
Nature genetics 47 (9), 979-986, 2015
20382015
A systematic survey of loss-of-function variants in human protein-coding genes
DG MacArthur, S Balasubramanian, A Frankish, N Huang, J Morris, ...
Science 335 (6070), 823-828, 2012
12712012
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
KM De Lange, L Moutsianas, JC Lee, CA Lamb, Y Luo, NA Kennedy, ...
Nature genetics 49 (2), 256-261, 2017
9452017
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression
BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ...
Science 343 (6175), 1246949, 2014
7522014
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
I Cleynen, G Boucher, L Jostins, LP Schumm, S Zeissig, T Ahmad, ...
The Lancet 387 (10014), 156-167, 2016
7222016
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
D Ellinghaus, L Jostins, SL Spain, A Cortes, J Bethune, B Han, YR Park, ...
Nature genetics 48 (5), 510-518, 2016
6242016
Fine-mapping inflammatory bowel disease loci to single-variant resolution
H Huang, M Fang, L Jostins, M Umićević Mirkov, G Boucher, ...
Nature 547 (7662), 173-178, 2017
4952017
Integrative annotation of variants from 1092 humans: application to cancer genomics
E Khurana, Y Fu, V Colonna, XJ Mu, HM Kang, T Lappalainen, A Sboner, ...
Science 342 (6154), 1235587, 2013
4072013
Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel
O Delaneau, J Marchini
Nature communications 5 (1), 3934, 2014
3932014
Class II HLA interactions modulate genetic risk for multiple sclerosis
Nature genetics 47 (10), 1107-1113, 2015
3432015
Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis
JZ Liu, MA Almarri, DJ Gaffney, GF Mells, L Jostins, HJ Cordell, SJ Ducker, ...
Nature genetics 44 (10), 1137-1141, 2012
2802012
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
SG Ji, BD Juran, S Mucha, T Folseraas, L Jostins, E Melum, N Kumasaka, ...
Nature genetics 49 (2), 269-273, 2017
2362017
Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease
JC Lee, D Biasci, R Roberts, RB Gearry, JC Mansfield, T Ahmad, ...
Nature genetics 49 (2), 262-268, 2017
2302017
Negligible impact of rare autoimmune-locus coding-region variants on missing heritability
KA Hunt, V Mistry, NA Bockett, T Ahmad, M Ban, JN Barker, JC Barrett, ...
Nature 498 (7453), 232-235, 2013
2272013
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity
CA Dendrou, A Cortes, L Shipman, HG Evans, KE Attfield, L Jostins, ...
Science Translational Medicine 8 (363), 363ra149-363ra149, 2016
1902016
Genetic risk prediction in complex disease
L Jostins, JC Barrett
Human molecular genetics 20 (R2), R182-R188, 2011
1902011
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